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5. Smac mimetic Birinapant induces apoptosis and enhances TRAIL potency in inflammatory breast cancer cells in an IAP-dependent and TNF-α-independent mechanism. Allensworth JL; Sauer SJ; Lyerly HK; Morse MA; Devi GR Breast Cancer Res Treat; 2013 Jan; 137(2):359-71. PubMed ID: 23225169 [TBL] [Abstract][Full Text] [Related]
6. Role of RIPK1 in SMAC mimetics-induced apoptosis in primary human HIV-infected macrophages. Caballero RE; Dong SXM; Gajanayaka N; Ali H; Cassol E; Cameron WD; Korneluk R; Tremblay MJ; Angel JB; Kumar A Sci Rep; 2021 Nov; 11(1):22901. PubMed ID: 34824340 [TBL] [Abstract][Full Text] [Related]
7. Potent and selective small-molecule inhibitors of cIAP1/2 proteins reveal that the binding of Smac mimetics to XIAP BIR3 is not required for their effective induction of cell death in tumor cells. Sun H; Lu J; Liu L; Yang CY; Wang S ACS Chem Biol; 2014 Apr; 9(4):994-1002. PubMed ID: 24521431 [TBL] [Abstract][Full Text] [Related]
8. Critical role for antiapoptotic Bcl-xL and Mcl-1 in human macrophage survival and cellular IAP1/2 (cIAP1/2) in resistance to HIV-Vpr-induced apoptosis. Busca A; Saxena M; Kumar A J Biol Chem; 2012 Apr; 287(18):15118-33. PubMed ID: 22403404 [TBL] [Abstract][Full Text] [Related]
9. Inhibitor of Apoptosis Protein-1 Regulates Tumor Necrosis Factor-Mediated Destruction of Intestinal Epithelial Cells. Grabinger T; Bode KJ; Demgenski J; Seitz C; Delgado ME; Kostadinova F; Reinhold C; Etemadi N; Wilhelm S; Schweinlin M; Hänggi K; Knop J; Hauck C; Walles H; Silke J; Wajant H; Nachbur U; W Wei-Lynn W; Brunner T Gastroenterology; 2017 Mar; 152(4):867-879. PubMed ID: 27889570 [TBL] [Abstract][Full Text] [Related]
10. SMAC Mimetic Birinapant plus Radiation Eradicates Human Head and Neck Cancers with Genomic Amplifications of Cell Death Genes FADD and BIRC2. Eytan DF; Snow GE; Carlson S; Derakhshan A; Saleh A; Schiltz S; Cheng H; Mohan S; Cornelius S; Coupar J; Sowers AL; Hernandez L; Mitchell JB; Annunziata CM; Chen Z; Van Waes C Cancer Res; 2016 Sep; 76(18):5442-5454. PubMed ID: 27469115 [TBL] [Abstract][Full Text] [Related]
11. Induction of a Na Zhang G; Luk BT; Hamidy M; Zhang L; Spector SA Autophagy; 2018; 14(8):1359-1375. PubMed ID: 29962265 [TBL] [Abstract][Full Text] [Related]
12. Small-molecule SMAC mimetics as new cancer therapeutics. Bai L; Smith DC; Wang S Pharmacol Ther; 2014 Oct; 144(1):82-95. PubMed ID: 24841289 [TBL] [Abstract][Full Text] [Related]
13. Apoptosis repressor with caspase recruitment domain modulates second mitochondrial-derived activator of caspases mimetic-induced cell death through BIRC2/MAP3K14 signalling in acute myeloid leukaemia. Mak PY; Mak DH; Ruvolo V; Jacamo R; Kornblau SM; Kantarjian H; Andreeff M; Carter BZ Br J Haematol; 2014 Nov; 167(3):376-84. PubMed ID: 25079338 [TBL] [Abstract][Full Text] [Related]
14. X-linked inhibitor of apoptosis (XIAP) blocks Apo2 ligand/tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis of prostate cancer cells in the presence of mitochondrial activation: sensitization by overexpression of second mitochondria-derived activator of caspase/direct IAP-binding protein with low pl (Smac/DIABLO). Ng CP; Bonavida B Mol Cancer Ther; 2002 Oct; 1(12):1051-8. PubMed ID: 12481428 [TBL] [Abstract][Full Text] [Related]
15. Novel SMAC-mimetics synergistically stimulate melanoma cell death in combination with TRAIL and Bortezomib. Lecis D; Drago C; Manzoni L; Seneci P; Scolastico C; Mastrangelo E; Bolognesi M; Anichini A; Kashkar H; Walczak H; Delia D Br J Cancer; 2010 Jun; 102(12):1707-16. PubMed ID: 20461078 [TBL] [Abstract][Full Text] [Related]
16. Smac mimetics can provoke lytic cell death that is neither apoptotic nor necroptotic. Miles MA; Caruso S; Baxter AA; Poon IKH; Hawkins CJ Apoptosis; 2020 Aug; 25(7-8):500-518. PubMed ID: 32440848 [TBL] [Abstract][Full Text] [Related]
17. Smac mimetics in combination with TRAIL selectively target cancer stem cells in nasopharyngeal carcinoma. Wu MS; Wang GF; Zhao ZQ; Liang Y; Wang HB; Wu MY; Min P; Chen LZ; Feng QS; Bei JX; Zeng YX; Yang D Mol Cancer Ther; 2013 Sep; 12(9):1728-37. PubMed ID: 23699656 [TBL] [Abstract][Full Text] [Related]
18. Smac mimetic triggers necroptosis in pancreatic carcinoma cells when caspase activation is blocked. Hannes S; Abhari BA; Fulda S Cancer Lett; 2016 Sep; 380(1):31-8. PubMed ID: 27267809 [TBL] [Abstract][Full Text] [Related]
19. Design of small-molecule peptidic and nonpeptidic Smac mimetics. Sun H; Nikolovska-Coleska Z; Yang CY; Qian D; Lu J; Qiu S; Bai L; Peng Y; Cai Q; Wang S Acc Chem Res; 2008 Oct; 41(10):1264-77. PubMed ID: 18937395 [TBL] [Abstract][Full Text] [Related]
20. Molecular determinants of the caspase-promoting activity of Smac/DIABLO and its role in the death receptor pathway. Srinivasula SM; Datta P; Fan XJ; Fernandes-Alnemri T; Huang Z; Alnemri ES J Biol Chem; 2000 Nov; 275(46):36152-7. PubMed ID: 10950947 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]