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2. PBK promotes aggressive phenotypes of cervical cancer through ERK/c-Myc signaling pathway. Ma H; Han F; Yan X; Qi G; Li Y; Li R; Yan S; Yuan C; Song K; Kong B J Cell Physiol; 2021 Apr; 236(4):2767-2781. PubMed ID: 33184870 [TBL] [Abstract][Full Text] [Related]
3. Targeting PDZ-binding kinase is anti-tumorigenic in novel preclinical models of ACC. Kar A; Zhang Y; Yacob BW; Saeed J; Tompkins KD; Bagby SM; Pitts TM; Somerset H; Leong S; Wierman ME; Kiseljak-Vassiliades K Endocr Relat Cancer; 2019 Oct; 26(10):765-778. PubMed ID: 31325906 [TBL] [Abstract][Full Text] [Related]
4. Targeting PBK/TOPK decreases growth and survival of glioma initiating cells in vitro and attenuates tumor growth in vivo. Joel M; Mughal AA; Grieg Z; Murrell W; Palmero S; Mikkelsen B; Fjerdingstad HB; Sandberg CJ; Behnan J; Glover JC; Langmoen IA; Stangeland B Mol Cancer; 2015 Jun; 14():121. PubMed ID: 26081429 [TBL] [Abstract][Full Text] [Related]
5. Mitotic kinase PBK/TOPK as a therapeutic target for adult T‑cell leukemia/lymphoma. Ishikawa C; Senba M; Mori N Int J Oncol; 2018 Aug; 53(2):801-814. PubMed ID: 29901068 [TBL] [Abstract][Full Text] [Related]
6. Potent anti-myeloma activity of the TOPK inhibitor OTS514 in pre-clinical models. Stefka AT; Johnson D; Rosebeck S; Park JH; Nakamura Y; Jakubowiak AJ Cancer Med; 2020 Jan; 9(1):324-334. PubMed ID: 31714026 [TBL] [Abstract][Full Text] [Related]
7. PBK, targeted by EVI1, promotes metastasis and confers cisplatin resistance through inducing autophagy in high-grade serous ovarian carcinoma. Ma H; Li Y; Wang X; Wu H; Qi G; Li R; Yang N; Gao M; Yan S; Yuan C; Kong B Cell Death Dis; 2019 Feb; 10(3):166. PubMed ID: 30778048 [TBL] [Abstract][Full Text] [Related]
9. PDZ-binding kinase inhibitor OTS514 suppresses the proliferation of oral squamous carcinoma cells. Kato M; Ota A; Ono T; Karnan S; Hyodo T; Rahman ML; Hasan MN; Onda M; Kondo S; Ito K; Furuhashi A; Hayashi T; Konishi H; Tsuzuki S; Hosokawa Y; Kazaoka Y Oral Dis; 2024 Mar; 30(2):223-234. PubMed ID: 36799330 [TBL] [Abstract][Full Text] [Related]
10. Baicalin suppresses lung cancer growth by targeting PDZ-binding kinase/T-LAK cell-originated protein kinase. Diao X; Yang D; Chen Y; Liu W Biosci Rep; 2019 Apr; 39(4):. PubMed ID: 30898980 [TBL] [Abstract][Full Text] [Related]
11. Gossypetin Inhibits Solar-UV Induced Cutaneous Basal Cell Carcinoma Through Direct Inhibiting PBK/TOPK Protein Kinase. Wang L; Zhang Z; Ge R; Zhang J; Liu W; Mou K; Lv S; Mu X Anticancer Agents Med Chem; 2019; 19(8):1029-1036. PubMed ID: 30827262 [TBL] [Abstract][Full Text] [Related]
12. PBK/TOPK Inhibitor Suppresses the Progression of Prolactinomas. Zhu K; Cheng X; Wang S; Zhang H; Zhang Y; Wang X; Chen Y; Wu J Front Endocrinol (Lausanne); 2021; 12():706909. PubMed ID: 35126305 [TBL] [Abstract][Full Text] [Related]
13. miR-216b promotes cell growth and enhances chemosensitivity of colorectal cancer by suppressing PDZ-binding kinase. Zou J; Kuang W; Hu J; Rao H Biochem Biophys Res Commun; 2017 Jun; 488(2):247-252. PubMed ID: 28373071 [TBL] [Abstract][Full Text] [Related]
14. PDZ binding kinase (PBK) is a theranostic target for nasopharyngeal carcinoma: driving tumor growth via ROS signaling and correlating with patient survival. Wang MY; Lin ZR; Cao Y; Zheng LS; Peng LX; Sun R; Meng DF; Xie P; Yang JP; Cao L; Xu L; Huang BJ; Qian CN Oncotarget; 2016 May; 7(18):26604-16. PubMed ID: 27049917 [TBL] [Abstract][Full Text] [Related]
15. PDZ binding kinase, regulated by FoxM1, enhances malignant phenotype via activation of β-Catenin signaling in hepatocellular carcinoma. Yang YF; Pan YH; Cao Y; Fu J; Yang X; Zhang MF; Tian QH Oncotarget; 2017 Jul; 8(29):47195-47205. PubMed ID: 28525379 [TBL] [Abstract][Full Text] [Related]
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17. Overexpression of PDZ-binding kinase confers malignant phenotype in prostate cancer via the regulation of E2F1. Chen JH; Liang YX; He HC; Chen JY; Lu JM; Chen G; Lin ZY; Fu X; Ling XH; Han ZD; Jiang FN; Zhong WD Int J Biol Macromol; 2015 Nov; 81():615-23. PubMed ID: 26314905 [TBL] [Abstract][Full Text] [Related]
18. Radiation-inducible miR-770-5p sensitizes tumors to radiation through direct targeting of PDZ-binding kinase. Lee HC; Her NG; Kang D; Jung SH; Shin J; Lee M; Bae IH; Kim YN; Park HJ; Ko YG; Lee JS Cell Death Dis; 2017 Mar; 8(3):e2693. PubMed ID: 28333152 [TBL] [Abstract][Full Text] [Related]
19. PBK/TOPK interacts with the DBD domain of tumor suppressor p53 and modulates expression of transcriptional targets including p21. Hu F; Gartenhaus RB; Eichberg D; Liu Z; Fang HB; Rapoport AP Oncogene; 2010 Oct; 29(40):5464-74. PubMed ID: 20622899 [TBL] [Abstract][Full Text] [Related]
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