These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

311 related articles for article (PubMed ID: 32732288)

  • 1. TGFβ acts through PDGFRβ to activate mTORC1 via the Akt/PRAS40 axis and causes glomerular mesangial cell hypertrophy and matrix protein expression.
    Maity S; Das F; Kasinath BS; Ghosh-Choudhury N; Ghosh Choudhury G
    J Biol Chem; 2020 Oct; 295(42):14262-14278. PubMed ID: 32732288
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Tyrosines-740/751 of PDGFRβ contribute to the activation of Akt/Hif1α/TGFβ nexus to drive high glucose-induced glomerular mesangial cell hypertrophy.
    Das F; Ghosh-Choudhury N; Kasinath BS; Choudhury GG
    Cell Signal; 2018 Jan; 42():44-53. PubMed ID: 28951244
    [TBL] [Abstract][Full Text] [Related]  

  • 3. TGFβ-stimulated microRNA-21 utilizes PTEN to orchestrate AKT/mTORC1 signaling for mesangial cell hypertrophy and matrix expansion.
    Dey N; Ghosh-Choudhury N; Kasinath BS; Choudhury GG
    PLoS One; 2012; 7(8):e42316. PubMed ID: 22879939
    [TBL] [Abstract][Full Text] [Related]  

  • 4. PDGF receptor-β uses Akt/mTORC1 signaling node to promote high glucose-induced renal proximal tubular cell collagen I (α2) expression.
    Das F; Ghosh-Choudhury N; Venkatesan B; Kasinath BS; Ghosh Choudhury G
    Am J Physiol Renal Physiol; 2017 Aug; 313(2):F291-F307. PubMed ID: 28424212
    [TBL] [Abstract][Full Text] [Related]  

  • 5. High glucose forces a positive feedback loop connecting Akt kinase and FoxO1 transcription factor to activate mTORC1 kinase for mesangial cell hypertrophy and matrix protein expression.
    Das F; Ghosh-Choudhury N; Dey N; Bera A; Mariappan MM; Kasinath BS; Ghosh Choudhury G
    J Biol Chem; 2014 Nov; 289(47):32703-16. PubMed ID: 25288788
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Hydrophobic motif site-phosphorylated protein kinase CβII between mTORC2 and Akt regulates high glucose-induced mesangial cell hypertrophy.
    Das F; Ghosh-Choudhury N; Mariappan MM; Kasinath BS; Choudhury GG
    Am J Physiol Cell Physiol; 2016 Apr; 310(7):C583-96. PubMed ID: 26739493
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Akt2 causes TGFβ-induced deptor downregulation facilitating mTOR to drive podocyte hypertrophy and matrix protein expression.
    Das F; Ghosh-Choudhury N; Lee DY; Gorin Y; Kasinath BS; Choudhury GG
    PLoS One; 2018; 13(11):e0207285. PubMed ID: 30444896
    [TBL] [Abstract][Full Text] [Related]  

  • 8. microRNA-181a downregulates deptor for TGFβ-induced glomerular mesangial cell hypertrophy and matrix protein expression.
    Maity S; Bera A; Ghosh-Choudhury N; Das F; Kasinath BS; Choudhury GG
    Exp Cell Res; 2018 Mar; 364(1):5-15. PubMed ID: 29397070
    [TBL] [Abstract][Full Text] [Related]  

  • 9. TGFβ-induced PI 3 kinase-dependent Mnk-1 activation is necessary for Ser-209 phosphorylation of eIF4E and mesangial cell hypertrophy.
    Das F; Ghosh-Choudhury N; Bera A; Kasinath BS; Choudhury GG
    J Cell Physiol; 2013 Jul; 228(7):1617-26. PubMed ID: 23359369
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Reciprocal regulation of miR-214 and PTEN by high glucose regulates renal glomerular mesangial and proximal tubular epithelial cell hypertrophy and matrix expansion.
    Bera A; Das F; Ghosh-Choudhury N; Mariappan MM; Kasinath BS; Ghosh Choudhury G
    Am J Physiol Cell Physiol; 2017 Oct; 313(4):C430-C447. PubMed ID: 28701356
    [TBL] [Abstract][Full Text] [Related]  

  • 11. High glucose enhances microRNA-26a to activate mTORC1 for mesangial cell hypertrophy and matrix protein expression.
    Dey N; Bera A; Das F; Ghosh-Choudhury N; Kasinath BS; Choudhury GG
    Cell Signal; 2015 Jul; 27(7):1276-85. PubMed ID: 25797045
    [TBL] [Abstract][Full Text] [Related]  

  • 12. PRAS40 acts as a nodal regulator of high glucose-induced TORC1 activation in glomerular mesangial cell hypertrophy.
    Dey N; Ghosh-Choudhury N; Das F; Li X; Venkatesan B; Barnes JL; Kasinath BS; Ghosh Choudhury G
    J Cell Physiol; 2010 Oct; 225(1):27-41. PubMed ID: 20629086
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Tyrosine phosphorylation-dependent PI 3 kinase/Akt signal transduction regulates TGFbeta-induced fibronectin expression in mesangial cells.
    Ghosh Choudhury G; Abboud HE
    Cell Signal; 2004 Jan; 16(1):31-41. PubMed ID: 14607273
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Raptor-rictor axis in TGFbeta-induced protein synthesis.
    Das F; Ghosh-Choudhury N; Mahimainathan L; Venkatesan B; Feliers D; Riley DJ; Kasinath BS; Choudhury GG
    Cell Signal; 2008 Feb; 20(2):409-23. PubMed ID: 18068336
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Oncoprotein DJ-1 interacts with mTOR complexes to effect transcription factor Hif1α-dependent expression of collagen I (α2) during renal fibrosis.
    Das F; Ghosh-Choudhury N; Maity S; Kasinath BS; Choudhury GG
    J Biol Chem; 2022 Sep; 298(9):102246. PubMed ID: 35835217
    [TBL] [Abstract][Full Text] [Related]  

  • 16. High glucose upregulation of early-onset Parkinson's disease protein DJ-1 integrates the PRAS40/TORC1 axis to mesangial cell hypertrophy.
    Das F; Dey N; Venkatesan B; Kasinath BS; Ghosh-Choudhury N; Choudhury GG
    Cell Signal; 2011 Aug; 23(8):1311-9. PubMed ID: 21426932
    [TBL] [Abstract][Full Text] [Related]  

  • 17. PRR5, a novel component of mTOR complex 2, regulates platelet-derived growth factor receptor beta expression and signaling.
    Woo SY; Kim DH; Jun CB; Kim YM; Haar EV; Lee SI; Hegg JW; Bandhakavi S; Griffin TJ; Kim DH
    J Biol Chem; 2007 Aug; 282(35):25604-12. PubMed ID: 17599906
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Transforming growth factor β integrates Smad 3 to mechanistic target of rapamycin complexes to arrest deptor abundance for glomerular mesangial cell hypertrophy.
    Das F; Ghosh-Choudhury N; Bera A; Dey N; Abboud HE; Kasinath BS; Choudhury GG
    J Biol Chem; 2013 Mar; 288(11):7756-7768. PubMed ID: 23362262
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The mechanism of insulin-stimulated 4E-BP protein binding to mammalian target of rapamycin (mTOR) complex 1 and its contribution to mTOR complex 1 signaling.
    Rapley J; Oshiro N; Ortiz-Vega S; Avruch J
    J Biol Chem; 2011 Nov; 286(44):38043-38053. PubMed ID: 21914810
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Deacetylation of S6 kinase promotes high glucose-induced glomerular mesangial cell hypertrophy and matrix protein accumulation.
    Das F; Maity S; Ghosh-Choudhury N; Kasinath BS; Ghosh Choudhury G
    J Biol Chem; 2019 Jun; 294(24):9440-9460. PubMed ID: 31028173
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.