145 related articles for article (PubMed ID: 32733009)
1. Cross-talk between GLI transcription factors and FOXC1 promotes T-cell acute lymphoblastic leukemia dissemination.
Tosello V; Bongiovanni D; Liu J; Pan Q; Yan KK; Saccomani V; Van Trimpont M; Pizzi M; Mazzoni M; Dei Tos AP; Amadori A; Zanovello P; Van Vlierberghe P; Yu J; Piovan E
Leukemia; 2021 Apr; 35(4):984-1000. PubMed ID: 32733009
[TBL] [Abstract][Full Text] [Related]
2. Responsiveness to Hedgehog Pathway Inhibitors in T-Cell Acute Lymphoblastic Leukemia Cells Is Highly Dependent on 5'AMP-Activated Kinase Inactivation.
Tosello V; Bongiovanni D; Di Martino L; Franchin C; Zanovello P; Arrigoni G; Piovan E
Int J Mol Sci; 2021 Jun; 22(12):. PubMed ID: 34203724
[TBL] [Abstract][Full Text] [Related]
3. In vitro and in vivo inhibition of breast cancer cell growth by targeting the Hedgehog/GLI pathway with SMO (GDC-0449) or GLI (GANT-61) inhibitors.
Benvenuto M; Masuelli L; De Smaele E; Fantini M; Mattera R; Cucchi D; Bonanno E; Di Stefano E; Frajese GV; Orlandi A; Screpanti I; Gulino A; Modesti A; Bei R
Oncotarget; 2016 Feb; 7(8):9250-70. PubMed ID: 26843616
[TBL] [Abstract][Full Text] [Related]
4. Hedgehog signaling and the Gli code in stem cells, cancer, and metastases.
Ruiz i Altaba A
Sci Signal; 2011 Nov; 4(200):pt9. PubMed ID: 22114144
[TBL] [Abstract][Full Text] [Related]
5. Inhibition of hedgehog signaling by GANT58 induces apoptosis and shows synergistic antitumor activity with AKT inhibitor in acute T cell leukemia cells.
Hou X; Chen X; Zhang P; Fan Y; Ma A; Pang T; Song Z; Jin Y; Hao W; Liu F; Wang W; Wang Y
Biochimie; 2014 Jun; 101():50-9. PubMed ID: 24394624
[TBL] [Abstract][Full Text] [Related]
6. Hedgehog pathway activation in T-cell acute lymphoblastic leukemia predicts response to SMO and GLI1 inhibitors.
Dagklis A; Demeyer S; De Bie J; Radaelli E; Pauwels D; Degryse S; Gielen O; Vicente C; Vandepoel R; Geerdens E; Uyttebroeck A; Boeckx N; de Bock CE; Cools J
Blood; 2016 Dec; 128(23):2642-2654. PubMed ID: 27694322
[TBL] [Abstract][Full Text] [Related]
7. HEDGEHOG/GLI-E2F1 axis modulates iASPP expression and function and regulates melanoma cell growth.
Pandolfi S; Montagnani V; Lapucci A; Stecca B
Cell Death Differ; 2015 Dec; 22(12):2006-19. PubMed ID: 26024388
[TBL] [Abstract][Full Text] [Related]
8. Crosstalk between Hedgehog pathway and the glucocorticoid receptor pathway as a basis for combination therapy in T-cell acute lymphoblastic leukemia.
Bongiovanni D; Tosello V; Saccomani V; Dalla Santa S; Amadori A; Zanovello P; Piovan E
Oncogene; 2020 Oct; 39(42):6544-6555. PubMed ID: 32917954
[TBL] [Abstract][Full Text] [Related]
9. The relevance of PTEN-AKT in relation to NOTCH1-directed treatment strategies in T-cell acute lymphoblastic leukemia.
Mendes RD; Canté-Barrett K; Pieters R; Meijerink JP
Haematologica; 2016 Sep; 101(9):1010-7. PubMed ID: 27582570
[TBL] [Abstract][Full Text] [Related]
10. GLI1/GLI2 functional interplay is required to control Hedgehog/GLI targets gene expression.
Tolosa EJ; Fernandez-Barrena MG; Iguchi E; McCleary-Wheeler AL; Carr RM; Almada LL; Flores LF; Vera RE; Alfonse GW; Marks DL; Hogenson TL; Vrabel AM; Horn IP; Koenig AN; Safgren SL; Sigafoos AN; Erkan M; Romecin-Duran PA; Sarabia Gonzalez A; Zhou B; Javelaud D; Marsaud V; Graham RP; Mauviel A; Elsawa SF; Fernandez-Zapico ME
Biochem J; 2020 Sep; 477(17):3131-3145. PubMed ID: 32766732
[TBL] [Abstract][Full Text] [Related]
11. Aberrant activation of hedgehog signaling promotes cell proliferation via the transcriptional activation of forkhead Box M1 in colorectal cancer cells.
Wang D; Hu G; Du Y; Zhang C; Lu Q; Lv N; Luo S
J Exp Clin Cancer Res; 2017 Feb; 36(1):23. PubMed ID: 28148279
[TBL] [Abstract][Full Text] [Related]
12. The prognostic significance and therapeutic potential of hedgehog signaling in intrahepatic cholangiocellular carcinoma.
Tang L; Tan YX; Jiang BG; Pan YF; Li SX; Yang GZ; Wang M; Wang Q; Zhang J; Zhou WP; Dong LW; Wang HY
Clin Cancer Res; 2013 Apr; 19(8):2014-24. PubMed ID: 23493353
[TBL] [Abstract][Full Text] [Related]
13. Melanomas require HEDGEHOG-GLI signaling regulated by interactions between GLI1 and the RAS-MEK/AKT pathways.
Stecca B; Mas C; Clement V; Zbinden M; Correa R; Piguet V; Beermann F; Ruiz i Altaba A
Proc Natl Acad Sci U S A; 2007 Apr; 104(14):5895-900. PubMed ID: 17392427
[TBL] [Abstract][Full Text] [Related]
14. Gli Transcription Factors Mediate the Oncogenic Transformation of Prostate Basal Cells Induced by a Kras-Androgen Receptor Axis.
Wu M; Ingram L; Tolosa EJ; Vera RE; Li Q; Kim S; Ma Y; Spyropoulos DD; Beharry Z; Huang J; Fernandez-Zapico ME; Cai H
J Biol Chem; 2016 Dec; 291(49):25749-25760. PubMed ID: 27760825
[TBL] [Abstract][Full Text] [Related]
15. A Critical Function for the Transcription Factors GLI1 and GLI2 in the Proliferation and Survival of Human Mast Cells.
Falduto GH; Pfeiffer A; Zhang Q; Yin Y; Metcalfe DD; Olivera A
Front Immunol; 2022; 13():841045. PubMed ID: 35251038
[TBL] [Abstract][Full Text] [Related]
16. CXCR4 Is Required for Leukemia-Initiating Cell Activity in T Cell Acute Lymphoblastic Leukemia.
Passaro D; Irigoyen M; Catherinet C; Gachet S; Da Costa De Jesus C; Lasgi C; Tran Quang C; Ghysdael J
Cancer Cell; 2015 Jun; 27(6):769-79. PubMed ID: 26058076
[TBL] [Abstract][Full Text] [Related]
17. GANT-61 and GDC-0449 induce apoptosis of prostate cancer stem cells through a GLI-dependent mechanism.
Tong W; Qiu L; Qi M; Liu J; Hu K; Lin W; Huang Y; Fu J
J Cell Biochem; 2018 Apr; 119(4):3641-3652. PubMed ID: 29231999
[TBL] [Abstract][Full Text] [Related]
18. Unique and overlapping GLI1 and GLI2 transcriptional targets in neoplastic chondrocytes.
Ali SA; Niu B; Cheah KSE; Alman B
PLoS One; 2019; 14(1):e0211333. PubMed ID: 30695055
[TBL] [Abstract][Full Text] [Related]
19. Targeting of sonic hedgehog-GLI signaling: a potential strategy to improve therapy for mantle cell lymphoma.
Hegde GV; Munger CM; Emanuel K; Joshi AD; Greiner TC; Weisenburger DD; Vose JM; Joshi SS
Mol Cancer Ther; 2008 Jun; 7(6):1450-60. PubMed ID: 18524848
[TBL] [Abstract][Full Text] [Related]
20. Integrative genomic analyses on GLI1: positive regulation of GLI1 by Hedgehog-GLI, TGFbeta-Smads, and RTK-PI3K-AKT signals, and negative regulation of GLI1 by Notch-CSL-HES/HEY, and GPCR-Gs-PKA signals.
Katoh Y; Katoh M
Int J Oncol; 2009 Jul; 35(1):187-92. PubMed ID: 19513567
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
