These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

216 related articles for article (PubMed ID: 32735323)

  • 1. XIAP Protects Retinal Ganglion Cells in the Mutant ND4 Mouse Model of Leber Hereditary Optic Neuropathy.
    Wassmer SJ; De Repentigny Y; Sheppard D; Lagali PS; Fang L; Coupland SG; Kothary R; Guy J; Hauswirth WW; Tsilfidis C
    Invest Ophthalmol Vis Sci; 2020 Jul; 61(8):49. PubMed ID: 32735323
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mutant NADH dehydrogenase subunit 4 gene delivery to mitochondria by targeting sequence-modified adeno-associated virus induces visual loss and optic atrophy in mice.
    Yu H; Ozdemir SS; Koilkonda RD; Chou TH; Porciatti V; Chiodo V; Boye SL; Hauswirth WW; Lewin AS; Guy J
    Mol Vis; 2012; 18():1668-83. PubMed ID: 22773905
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Safety and effects of the vector for the Leber hereditary optic neuropathy gene therapy clinical trial.
    Koilkonda RD; Yu H; Chou TH; Feuer WJ; Ruggeri M; Porciatti V; Tse D; Hauswirth WW; Chiodo V; Boye SL; Lewin AS; Neuringer M; Renner L; Guy J
    JAMA Ophthalmol; 2014 Apr; 132(4):409-20. PubMed ID: 24457989
    [TBL] [Abstract][Full Text] [Related]  

  • 4. LHON gene therapy vector prevents visual loss and optic neuropathy induced by G11778A mutant mitochondrial DNA: biodistribution and toxicology profile.
    Koilkonda R; Yu H; Talla V; Porciatti V; Feuer WJ; Hauswirth WW; Chiodo V; Erger KE; Boye SL; Lewin AS; Conlon TJ; Renner L; Neuringer M; Detrisac C; Guy J
    Invest Ophthalmol Vis Sci; 2014 Oct; 55(12):7739-53. PubMed ID: 25342621
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The mutant human ND4 subunit of complex I induces optic neuropathy in the mouse.
    Qi X; Sun L; Lewin AS; Hauswirth WW; Guy J
    Invest Ophthalmol Vis Sci; 2007 Jan; 48(1):1-10. PubMed ID: 17197509
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Cell therapy using retinal progenitor cells shows therapeutic effect in a chemically-induced rotenone mouse model of Leber hereditary optic neuropathy.
    Mansergh FC; Chadderton N; Kenna PF; Gobbo OL; Farrar GJ
    Eur J Hum Genet; 2014 Nov; 22(11):1314-20. PubMed ID: 24569607
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Leber hereditary optic neuropathy gene therapy clinical trial recruitment: year 1.
    Lam BL; Feuer WJ; Abukhalil F; Porciatti V; Hauswirth WW; Guy J
    Arch Ophthalmol; 2010 Sep; 128(9):1129-35. PubMed ID: 20837795
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Trial end points and natural history in patients with G11778A Leber hereditary optic neuropathy : preparation for gene therapy clinical trial.
    Lam BL; Feuer WJ; Schiffman JC; Porciatti V; Vandenbroucke R; Rosa PR; Gregori G; Guy J
    JAMA Ophthalmol; 2014 Apr; 132(4):428-36. PubMed ID: 24525545
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Induction of rapid and highly efficient expression of the human ND4 complex I subunit in the mouse visual system by self-complementary adeno-associated virus.
    Koilkonda RD; Chou TH; Porciatti V; Hauswirth WW; Guy J
    Arch Ophthalmol; 2010 Jul; 128(7):876-83. PubMed ID: 20625049
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Efficiency and safety of AAV-mediated gene delivery of the human ND4 complex I subunit in the mouse visual system.
    Guy J; Qi X; Koilkonda RD; Arguello T; Chou TH; Ruggeri M; Porciatti V; Lewin AS; Hauswirth WW
    Invest Ophthalmol Vis Sci; 2009 Sep; 50(9):4205-14. PubMed ID: 19387075
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Mitochondrial transport mediates survival of retinal ganglion cells in affected LHON patients.
    Yang TC; Yarmishyn AA; Yang YP; Lu PC; Chou SJ; Wang ML; Lin TC; Hwang DK; Chou YB; Chen SJ; Yu WK; Wang AG; Hsu CC; Chiou SH
    Hum Mol Genet; 2020 Jun; 29(9):1454-1464. PubMed ID: 32277753
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Immune Response and Intraocular Inflammation in Patients With Leber Hereditary Optic Neuropathy Treated With Intravitreal Injection of Recombinant Adeno-Associated Virus 2 Carrying the ND4 Gene: A Secondary Analysis of a Phase 1/2 Clinical Trial.
    Bouquet C; Vignal Clermont C; Galy A; Fitoussi S; Blouin L; Munk MR; Valero S; Meunier S; Katz B; Sahel JA; Thomasson N
    JAMA Ophthalmol; 2019 Apr; 137(4):399-406. PubMed ID: 30730541
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Successful amelioration of mitochondrial optic neuropathy using the yeast NDI1 gene in a rat animal model.
    Marella M; Seo BB; Thomas BB; Matsuno-Yagi A; Yagi T
    PLoS One; 2010 Jul; 5(7):e11472. PubMed ID: 20628600
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Leber hereditary optic neuropathy gene therapy.
    Lam BL
    Curr Opin Ophthalmol; 2024 May; 35(3):244-251. PubMed ID: 38117686
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Variation in retinal nerve fiber layer thickness at different stages of Leber's hereditary optic neuropathy in patients with the ND4 G11778A mutation.
    Tian Z; Li X; Zheng W; Li B; Zhang Y
    Semin Ophthalmol; 2022 May; 37(4):496-501. PubMed ID: 34702118
    [TBL] [Abstract][Full Text] [Related]  

  • 16. [Clinical research progress of gene therapy for Leber hereditary optic neuropathy].
    Wu YJ; Li WS
    Zhonghua Yan Ke Za Zhi; 2018 Aug; 54(8):636-640. PubMed ID: 30107658
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Leber's Hereditary Optic Neuropathy as a Promising Disease for Gene Therapy Development.
    Karaarslan C
    Adv Ther; 2019 Dec; 36(12):3299-3307. PubMed ID: 31605306
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Retinal damage promotes mitochondrial transfer in the visual system of a mouse model of Leber hereditary optic neuropathy.
    Ezan P; Hardy E; Bemelmans A; Taiel M; Dossi E; Rouach N
    Neurobiol Dis; 2024 Oct; 201():106681. PubMed ID: 39332508
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Optical Coherence Tomography of the Retinal Ganglion Cell Complex in Leber's Hereditary Optic Neuropathy and Dominant Optic Atrophy.
    Asanad S; Tian JJ; Frousiakis S; Jiang JP; Kogachi K; Felix CM; Fatemeh D; Irvine AG; Ter-Zakarian A; Falavarjani KG; Barboni P; Karanjia R; Sadun AA
    Curr Eye Res; 2019 Jun; 44(6):638-644. PubMed ID: 30649972
    [No Abstract]   [Full Text] [Related]  

  • 20. Absence of lenadogene nolparvovec DNA in a brain tumor biopsy from a patient in the REVERSE clinical study, a case report.
    Newman NJ; Schniederjan M; Mendoza PR; Calkins DJ; Yu-Wai-Man P; Biousse V; Carelli V; Taiel M; Rugiero F; Singh P; Rogue A; Sahel JA; Ancian P
    BMC Neurol; 2022 Jul; 22(1):257. PubMed ID: 35820885
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.