165 related articles for article (PubMed ID: 32753483)
1. Development of Noonan syndrome by deregulation of allosteric SOS autoactivation.
Umutesi HG; Hoang HM; Johnson HE; Nam K; Heo J
J Biol Chem; 2020 Sep; 295(39):13651-13663. PubMed ID: 32753483
[TBL] [Abstract][Full Text] [Related]
2. Allosteric autoactivation of SOS and its kinetic mechanism.
Hoang HM; Umutesi HG; Heo J
Small GTPases; 2021 Jan; 12(1):44-59. PubMed ID: 30983499
[TBL] [Abstract][Full Text] [Related]
3. Structural analysis of autoinhibition in the Ras activator Son of sevenless.
Sondermann H; Soisson SM; Boykevisch S; Yang SS; Bar-Sagi D; Kuriyan J
Cell; 2004 Oct; 119(3):393-405. PubMed ID: 15507210
[TBL] [Abstract][Full Text] [Related]
4. Differences in flexibility underlie functional differences in the Ras activators son of sevenless and Ras guanine nucleotide releasing factor 1.
Freedman TS; Sondermann H; Kuchment O; Friedland GD; Kortemme T; Kuriyan J
Structure; 2009 Jan; 17(1):41-53. PubMed ID: 19141281
[TBL] [Abstract][Full Text] [Related]
5. The Interdependent Activation of Son-of-Sevenless and Ras.
Bandaru P; Kondo Y; Kuriyan J
Cold Spring Harb Perspect Med; 2019 Feb; 9(2):. PubMed ID: 29610148
[TBL] [Abstract][Full Text] [Related]
6. Noonan syndrome gain-of-function mutations in NRAS cause zebrafish gastrulation defects.
Runtuwene V; van Eekelen M; Overvoorde J; Rehmann H; Yntema HG; Nillesen WM; van Haeringen A; van der Burgt I; Burgering B; den Hertog J
Dis Model Mech; 2011 May; 4(3):393-9. PubMed ID: 21263000
[TBL] [Abstract][Full Text] [Related]
7. Regulation of Son of sevenless by the membrane-actin linker protein ezrin.
Geissler KJ; Jung MJ; Riecken LB; Sperka T; Cui Y; Schacke S; Merkel U; Markwart R; Rubio I; Than ME; Breithaupt C; Peuker S; Seifert R; Kaupp UB; Herrlich P; Morrison H
Proc Natl Acad Sci U S A; 2013 Dec; 110(51):20587-92. PubMed ID: 24297905
[TBL] [Abstract][Full Text] [Related]
8. Molecular assemblies of the catalytic domain of SOS with KRas and oncogenic mutants.
Moghadamchargari Z; Shirzadeh M; Liu C; Schrecke S; Packianathan C; Russell DH; Zhao M; Laganowsky A
Proc Natl Acad Sci U S A; 2021 Mar; 118(12):. PubMed ID: 33723061
[TBL] [Abstract][Full Text] [Related]
9. Structural basis of the atypical activation mechanism of KRAS
Bera AK; Lu J; Wales TE; Gondi S; Gurbani D; Nelson A; Engen JR; Westover KD
J Biol Chem; 2019 Sep; 294(38):13964-13972. PubMed ID: 31341022
[TBL] [Abstract][Full Text] [Related]
10. Monitoring Ras Interactions with the Nucleotide Exchange Factor Son of Sevenless (Sos) Using Site-specific NMR Reporter Signals and Intrinsic Fluorescence.
Vo U; Vajpai N; Flavell L; Bobby R; Breeze AL; Embrey KJ; Golovanov AP
J Biol Chem; 2016 Jan; 291(4):1703-1718. PubMed ID: 26565026
[TBL] [Abstract][Full Text] [Related]
11. Mutation-Specific Mechanisms of Hyperactivation of Noonan Syndrome SOS Molecules Detected with Single-molecule Imaging in Living Cells.
Nakamura Y; Umeki N; Abe M; Sako Y
Sci Rep; 2017 Oct; 7(1):14153. PubMed ID: 29074966
[TBL] [Abstract][Full Text] [Related]
12. Unusual interplay of two types of Ras activators, RasGRP and SOS, establishes sensitive and robust Ras activation in lymphocytes.
Roose JP; Mollenauer M; Ho M; Kurosaki T; Weiss A
Mol Cell Biol; 2007 Apr; 27(7):2732-45. PubMed ID: 17283063
[TBL] [Abstract][Full Text] [Related]
13. Activation of Ras requires the ERM-dependent link of actin to the plasma membrane.
Sperka T; Geissler KJ; Merkel U; Scholl I; Rubio I; Herrlich P; Morrison HL
PLoS One; 2011; 6(11):e27511. PubMed ID: 22132106
[TBL] [Abstract][Full Text] [Related]
14. Autoinhibition of Sos by intramolecular interactions.
Hall BE; Yang SS; Bar-Sagi D
Front Biosci; 2002 Jan; 7():d288-94. PubMed ID: 11779695
[TBL] [Abstract][Full Text] [Related]
15. Computational docking and solution x-ray scattering predict a membrane-interacting role for the histone domain of the Ras activator son of sevenless.
Sondermann H; Nagar B; Bar-Sagi D; Kuriyan J
Proc Natl Acad Sci U S A; 2005 Nov; 102(46):16632-7. PubMed ID: 16267129
[TBL] [Abstract][Full Text] [Related]
16. Molecular dynamics analysis of the structures of ras-guanine nucleotide exchange protein (SOS) bound to wild-type and oncogenic ras-p21. Identification of effector domains of SOS.
Chen JM; Friedman FK; Hyde MJ; Monaco R; Pincus MR
J Protein Chem; 1999 Nov; 18(8):867-74. PubMed ID: 10839623
[TBL] [Abstract][Full Text] [Related]
17. SOS GEFs in health and disease.
Baltanás FC; Zarich N; Rojas-Cabañeros JM; Santos E
Biochim Biophys Acta Rev Cancer; 2020 Dec; 1874(2):188445. PubMed ID: 33035641
[TBL] [Abstract][Full Text] [Related]
18. Germline KRAS mutations cause Noonan syndrome.
Schubbert S; Zenker M; Rowe SL; Böll S; Klein C; Bollag G; van der Burgt I; Musante L; Kalscheuer V; Wehner LE; Nguyen H; West B; Zhang KY; Sistermans E; Rauch A; Niemeyer CM; Shannon K; Kratz CP
Nat Genet; 2006 Mar; 38(3):331-6. PubMed ID: 16474405
[TBL] [Abstract][Full Text] [Related]
19. Mechanism of SOS PR-domain autoinhibition revealed by single-molecule assays on native protein from lysate.
Lee YK; Low-Nam ST; Chung JK; Hansen SD; Lam HYM; Alvarez S; Groves JT
Nat Commun; 2017 Apr; 8():15061. PubMed ID: 28452363
[TBL] [Abstract][Full Text] [Related]
20. Role of the histone domain in the autoinhibition and activation of the Ras activator Son of Sevenless.
Gureasko J; Kuchment O; Makino DL; Sondermann H; Bar-Sagi D; Kuriyan J
Proc Natl Acad Sci U S A; 2010 Feb; 107(8):3430-5. PubMed ID: 20133692
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
