134 related articles for article (PubMed ID: 32758860)
1. An orally available inverse agonist of estrogen-related receptor gamma showed expanded efficacy for the radioiodine therapy of poorly differentiated thyroid cancer.
Kim J; Hwang H; Yoon H; Lee JE; Oh JM; An H; Ji HD; Lee S; Cha E; Ma MJ; Kim DS; Lee SJ; Kadayat TM; Song J; Lee SW; Jeon JH; Park KG; Lee IK; Jeon YH; Chin J; Cho SJ
Eur J Med Chem; 2020 Nov; 205():112501. PubMed ID: 32758860
[TBL] [Abstract][Full Text] [Related]
2. Discovery of Potent, Selective, and Orally Bioavailable Estrogen-Related Receptor-γ Inverse Agonists To Restore the Sodium Iodide Symporter Function in Anaplastic Thyroid Cancer.
Kim J; Song J; Ji HD; Yoo EK; Lee JE; Lee SB; Oh JM; Lee S; Hwang JS; Yoon H; Kim DS; Lee SJ; Jeong M; Lee S; Kim KH; Choi HS; Lee SW; Park KG; Lee IK; Kim SH; Hwang H; Jeon YH; Chin J; Cho SJ
J Med Chem; 2019 Feb; 62(4):1837-1858. PubMed ID: 30657313
[TBL] [Abstract][Full Text] [Related]
3. A Novel Orally Active Inverse Agonist of Estrogen-related Receptor Gamma (ERRγ), DN200434, A Booster of NIS in Anaplastic Thyroid Cancer.
Singh TD; Song J; Kim J; Chin J; Ji HD; Lee JE; Lee SB; Yoon H; Yu JH; Kim SK; Yoon GS; Hwang H; Lee HW; Oh JM; Lee SW; Lee J; Choi HS; Na SY; Choi WI; Park YJ; Song YS; Kim YA; Lee IK; Cho SJ; Jeon YH
Clin Cancer Res; 2019 Aug; 25(16):5069-5081. PubMed ID: 31010838
[TBL] [Abstract][Full Text] [Related]
4. Inverse Agonist of Estrogen-Related Receptor γ Enhances Sodium Iodide Symporter Function Through Mitogen-Activated Protein Kinase Signaling in Anaplastic Thyroid Cancer Cells.
Singh TD; Jeong SY; Lee SW; Ha JH; Lee IK; Kim SH; Kim J; Cho SJ; Ahn BC; Lee J; Jeon YH
J Nucl Med; 2015 Nov; 56(11):1690-6. PubMed ID: 26338896
[TBL] [Abstract][Full Text] [Related]
5. An Inverse Agonist of Estrogen-Related Receptor Gamma, GSK5182, Enhances Na
Singh TD; Lee JE; Son KH; Lee BR; Kim SK; Gulwani D; Sarangthem V; Jeon YH
Cells; 2023 Feb; 12(3):. PubMed ID: 36766812
[TBL] [Abstract][Full Text] [Related]
6. Synthesis and biological evaluation of novel 4-hydroxytamoxifen analogs as estrogen-related receptor gamma inverse agonists.
Kim J; Chin J; Im CY; Yoo EK; Woo S; Hwang HJ; Cho JH; Seo KA; Song J; Hwang H; Kim KH; Kim ND; Yoon SK; Jeon JH; Yoon SY; Jeon YH; Choi HS; Lee IK; Kim SH; Cho SJ
Eur J Med Chem; 2016 Sep; 120():338-52. PubMed ID: 27236015
[TBL] [Abstract][Full Text] [Related]
7. Identification of novel inverse agonists of estrogen-related receptors ERRγ and ERRβ.
Yu DD; Huss JM; Li H; Forman BM
Bioorg Med Chem; 2017 Mar; 25(5):1585-1599. PubMed ID: 28189393
[TBL] [Abstract][Full Text] [Related]
8. Structure-based discovery of pyrazolamides as novel ERRγ inverse agonists.
Yang SH; Khadka DB; Han J; Na SY; Shin M; Kim DK; Oh BC; Kim EY; Choi HS; Cho WJ
Eur J Med Chem; 2023 Mar; 250():115174. PubMed ID: 36805944
[TBL] [Abstract][Full Text] [Related]
9. Identification of Selective ERRγ Inverse Agonists.
Kim J; Im CY; Yoo EK; Ma MJ; Kim SB; Hong E; Chin J; Hwang H; Lee S; Kim ND; Jeon JH; Lee IK; Jeon YH; Choi HS; Kim SH; Cho SJ
Molecules; 2016 Jan; 21(1):80. PubMed ID: 26771593
[TBL] [Abstract][Full Text] [Related]
10. X-ray crystal structures of the estrogen-related receptor-gamma ligand binding domain in three functional states reveal the molecular basis of small molecule regulation.
Wang L; Zuercher WJ; Consler TG; Lambert MH; Miller AB; Orband-Miller LA; McKee DD; Willson TM; Nolte RT
J Biol Chem; 2006 Dec; 281(49):37773-81. PubMed ID: 16990259
[TBL] [Abstract][Full Text] [Related]
11. Molecular dynamics of the ERRγ ligand-binding domain bound with agonist and inverse agonist.
Sasidharan S; Radhakrishnan K; Lee JY; Saudagar P; Gosu V; Shin D
PLoS One; 2023; 18(4):e0283364. PubMed ID: 37023008
[TBL] [Abstract][Full Text] [Related]
12. Structural basis for the deactivation of the estrogen-related receptor gamma by diethylstilbestrol or 4-hydroxytamoxifen and determinants of selectivity.
Greschik H; Flaig R; Renaud JP; Moras D
J Biol Chem; 2004 Aug; 279(32):33639-46. PubMed ID: 15161930
[TBL] [Abstract][Full Text] [Related]
13. Insights of a Lead Optimization Study and Biological Evaluation of Novel 4-Hydroxytamoxifen Analogs as Estrogen-Related Receptor γ (ERRγ) Inverse Agonists.
Kim J; Woo SY; Im CY; Yoo EK; Lee S; Kim HJ; Hwang HJ; Cho JH; Lee WS; Yoon H; Kim S; Kwon OB; Hwang H; Kim KH; Jeon JH; Singh TD; Kim SW; Hwang SY; Choi HS; Lee IK; Kim SH; Jeon YH; Chin J; Cho SJ
J Med Chem; 2016 Nov; 59(22):10209-10227. PubMed ID: 27805390
[TBL] [Abstract][Full Text] [Related]
14. Characterization of a selective inverse agonist for estrogen related receptor α as a potential agent for breast cancer.
Zhang L; Liu P; Chen H; Li Q; Chen L; Qi H; Shi X; Du Y
Eur J Pharmacol; 2016 Oct; 789():439-448. PubMed ID: 27498368
[TBL] [Abstract][Full Text] [Related]
15. Targeted Therapy in Thyroid Cancer: State of the Art.
Valerio L; Pieruzzi L; Giani C; Agate L; Bottici V; Lorusso L; Cappagli V; Puleo L; Matrone A; Viola D; Romei C; Ciampi R; Molinaro E; Elisei R
Clin Oncol (R Coll Radiol); 2017 May; 29(5):316-324. PubMed ID: 28318881
[TBL] [Abstract][Full Text] [Related]
16. Redifferentiating agents in non-radioiodine avid cancer.
Seregni E; Vellani C; Castellani MR; Maccauro M; Pallotti F; Scaramellini G; Guzzo M; Greco A
Q J Nucl Med Mol Imaging; 2009 Oct; 53(5):513-9. PubMed ID: 19910904
[TBL] [Abstract][Full Text] [Related]
17. Crystal structure of human estrogen-related receptor alpha in complex with a synthetic inverse agonist reveals its novel molecular mechanism.
Kallen J; Lattmann R; Beerli R; Blechschmidt A; Blommers MJ; Geiser M; Ottl J; Schlaeppi JM; Strauss A; Fournier B
J Biol Chem; 2007 Aug; 282(32):23231-9. PubMed ID: 17556356
[TBL] [Abstract][Full Text] [Related]
18. Reintroducing the Sodium-Iodide Symporter to Anaplastic Thyroid Carcinoma.
Schmohl KA; Dolp P; Schug C; Knoop K; Klutz K; Schwenk N; Bartenstein P; Nelson PJ; Ogris M; Wagner E; Spitzweg C
Thyroid; 2017 Dec; 27(12):1534-1543. PubMed ID: 29032724
[TBL] [Abstract][Full Text] [Related]
19. Estrogen-related receptor gamma induces cardiac hypertrophy by activating GATA4.
Kwon DH; Eom GH; Kee HJ; Nam YS; Cho YK; Kim DK; Koo JY; Kim HS; Nam KI; Kim KK; Lee IK; Park SB; Choi HS; Kook H
J Mol Cell Cardiol; 2013 Dec; 65():88-97. PubMed ID: 24083978
[TBL] [Abstract][Full Text] [Related]
20. Isolation and functional characterization of a novel endogenous inverse agonist of estrogen related receptors (ERRs) from human pregnancy urine.
Ghanbari F; Hebert-Losier A; Barry J; Poirier D; Giguere V; Mader S; Philip A
J Steroid Biochem Mol Biol; 2019 Jul; 191():105352. PubMed ID: 30954508
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]