These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

158 related articles for article (PubMed ID: 32761504)

  • 1. NMR fragment screening reveals a novel small molecule binding site near the catalytic surface of the disulfide-dithiol oxidoreductase enzyme DsbA from Burkholderia pseudomallei.
    Nebl S; Alwan WS; Williams ML; Sharma G; Taylor A; Doak BC; Wilde KL; McMahon RM; Halili MA; Martin JL; Capuano B; Fenwick RB; Mohanty B; Scanlon MJ
    J Biomol NMR; 2020 Nov; 74(10-11):595-611. PubMed ID: 32761504
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Disarming Burkholderia pseudomallei: structural and functional characterization of a disulfide oxidoreductase (DsbA) required for virulence in vivo.
    Ireland PM; McMahon RM; Marshall LE; Halili M; Furlong E; Tay S; Martin JL; Sarkar-Tyson M
    Antioxid Redox Signal; 2014 Feb; 20(4):606-17. PubMed ID: 23901809
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Identification and characterization of two drug-like fragments that bind to the same cryptic binding pocket of Burkholderia pseudomallei DsbA.
    Petit GA; Mohanty B; McMahon RM; Nebl S; Hilko DH; Wilde KL; Scanlon MJ; Martin JL; Halili MA
    Acta Crystallogr D Struct Biol; 2022 Jan; 78(Pt 1):75-90. PubMed ID: 34981764
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Virulence of the Melioidosis Pathogen Burkholderia pseudomallei Requires the Oxidoreductase Membrane Protein DsbB.
    McMahon RM; Ireland PM; Sarovich DS; Petit G; Jenkins CH; Sarkar-Tyson M; Currie BJ; Martin JL
    Infect Immun; 2018 May; 86(5):. PubMed ID: 29440370
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Leveraging structure determination with fragment screening for infectious disease drug targets: MECP synthase from Burkholderia pseudomallei.
    Begley DW; Hartley RC; Davies DR; Edwards TE; Leonard JT; Abendroth J; Burris CA; Bhandari J; Myler PJ; Staker BL; Stewart LJ
    J Struct Funct Genomics; 2011 Jul; 12(2):63-76. PubMed ID: 21359640
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The Fragment-Based Development of a Benzofuran Hit as a New Class of
    Duncan LF; Wang G; Ilyichova OV; Scanlon MJ; Heras B; Abbott BM
    Molecules; 2019 Oct; 24(20):. PubMed ID: 31635355
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Prediction of Burkholderia pseudomallei DsbA substrates identifies potential virulence factors and vaccine targets.
    Vezina B; Petit GA; Martin JL; Halili MA
    PLoS One; 2020; 15(11):e0241306. PubMed ID: 33216758
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Selective Binding of Small Molecules to Vibrio cholerae DsbA Offers a Starting Point for the Design of Novel Antibacterials.
    Wang G; Mohanty B; Williams ML; Doak BC; Dhouib R; Totsika M; McMahon RM; Sharma G; Zheng D; Bentley MR; Ka-Yan Chin Y; Horne J; Chalmers DK; Heras B; Scanlon MJ
    ChemMedChem; 2022 Mar; 17(6):e202100673. PubMed ID: 34978144
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Backbone and side chain 1H, 15N and 13C assignments for the oxidised and reduced forms of the oxidoreductase protein DsbA from Staphylococcus aureus.
    Williams ML; Chalmers DK; Martin JL; Scanlon MJ
    Biomol NMR Assign; 2010 Apr; 4(1):25-8. PubMed ID: 19936968
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Determination of ligand binding modes in weak protein-ligand complexes using sparse NMR data.
    Mohanty B; Williams ML; Doak BC; Vazirani M; Ilyichova O; Wang G; Bermel W; Simpson JS; Chalmers DK; King GF; Mobli M; Scanlon MJ
    J Biomol NMR; 2016 Nov; 66(3):195-208. PubMed ID: 27778134
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Burkholderia pseudomallei d-alanine-d-alanine ligase; detailed characterisation and assessment of a potential antibiotic drug target.
    Díaz-Sáez L; Torrie LS; McElroy SP; Gray D; Hunter WN
    FEBS J; 2019 Nov; 286(22):4509-4524. PubMed ID: 31260169
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Probing the flexibility of the DsbA oxidoreductase from Vibrio cholerae--a 15N - 1H heteronuclear NMR relaxation analysis of oxidized and reduced forms of DsbA.
    Horne J; d'Auvergne EJ; Coles M; Velkov T; Chin Y; Charman WN; Prankerd R; Gooley PR; Scanlon MJ
    J Mol Biol; 2007 Aug; 371(3):703-16. PubMed ID: 17585933
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Crystal structure and biophysical properties of Bacillus subtilis BdbD. An oxidizing thiol:disulfide oxidoreductase containing a novel metal site.
    Crow A; Lewin A; Hecht O; Carlsson Möller M; Moore GR; Hederstedt L; Le Brun NE
    J Biol Chem; 2009 Aug; 284(35):23719-33. PubMed ID: 19535335
    [TBL] [Abstract][Full Text] [Related]  

  • 14. NMR quality control of fragment libraries for screening.
    Sreeramulu S; Richter C; Kuehn T; Azzaoui K; Blommers MJJ; Del Conte R; Fragai M; Trieloff N; Schmieder P; Nazaré M; Specker E; Ivanov V; Oschkinat H; Banci L; Schwalbe H
    J Biomol NMR; 2020 Nov; 74(10-11):555-563. PubMed ID: 32533387
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The structure of sedoheptulose-7-phosphate isomerase from Burkholderia pseudomallei reveals a zinc binding site at the heart of the active site.
    Harmer NJ
    J Mol Biol; 2010 Jul; 400(3):379-92. PubMed ID: 20447408
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A novel FK-506-binding-like protein that lacks peptidyl-prolyl isomerase activity is involved in intracellular infection and in vivo virulence of Burkholderia pseudomallei.
    Norville IH; Breitbach K; Eske-Pogodda K; Harmer NJ; Sarkar-Tyson M; Titball RW; Steinmetz I
    Microbiology (Reading); 2011 Sep; 157(Pt 9):2629-2638. PubMed ID: 21680634
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Structural and Biochemical Characterization of Chlamydia trachomatis DsbA Reveals a Cysteine-Rich and Weakly Oxidising Oxidoreductase.
    Christensen S; Grøftehauge MK; Byriel K; Huston WM; Furlong E; Heras B; Martin JL; McMahon RM
    PLoS One; 2016; 11(12):e0168485. PubMed ID: 28030602
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Revisiting biomolecular NMR spectroscopy for promoting small-molecule drug discovery.
    Hanzawa H; Shimada T; Takahashi M; Takahashi H
    J Biomol NMR; 2020 Nov; 74(10-11):501-508. PubMed ID: 32306215
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structural Basis of a Thiol-Disulfide Oxidoreductase in the Hedgehog-Forming Actinobacterium Corynebacterium matruchotii.
    Luong TT; Tirgar R; Reardon-Robinson ME; Joachimiak A; Osipiuk J; Ton-That H
    J Bacteriol; 2018 May; 200(9):. PubMed ID: 29440253
    [TBL] [Abstract][Full Text] [Related]  

  • 20. AFN-1252 is a potent inhibitor of enoyl-ACP reductase from Burkholderia pseudomallei--Crystal structure, mode of action, and biological activity.
    Rao KN; Lakshminarasimhan A; Joseph S; Lekshmi SU; Lau MS; Takhi M; Sreenivas K; Nathan S; Yusof R; Abd Rahman N; Ramachandra M; Antony T; Subramanya H
    Protein Sci; 2015 May; 24(5):832-40. PubMed ID: 25644789
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.