These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

137 related articles for article (PubMed ID: 32761825)

  • 1. An Assay for Screening Potential Drug Candidates for Alzheimer's Disease That Act as Chaperones of the Transthyretin and Amyloid-β Peptides Interaction.
    Cotrina EY; Gimeno A; Llop J; Jiménez-Barbero J; Quintana J; Prohens R; Cardoso I; Arsequell G
    Chemistry; 2020 Dec; 26(72):17462-17469. PubMed ID: 32761825
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Targeting transthyretin in Alzheimer's disease: Drug discovery of small-molecule chaperones as disease-modifying drug candidates for Alzheimer's disease.
    Cotrina EY; Santos LM; Rivas J; Blasi D; Leite JP; Liz MA; Busquets MA; Planas A; Prohens R; Gimeno A; Jiménez-Barbero J; Gales L; Llop J; Quintana J; Cardoso I; Arsequell G
    Eur J Med Chem; 2021 Dec; 226():113847. PubMed ID: 34555615
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Calorimetric Studies of Binary and Ternary Molecular Interactions between Transthyretin, Aβ Peptides, and Small-Molecule Chaperones toward an Alternative Strategy for Alzheimer's Disease Drug Discovery.
    Cotrina EY; Gimeno A; Llop J; Jiménez-Barbero J; Quintana J; Valencia G; Cardoso I; Prohens R; Arsequell G
    J Med Chem; 2020 Mar; 63(6):3205-3214. PubMed ID: 32124607
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Transthyretin stabilization by iododiflunisal promotes amyloid-β peptide clearance, decreases its deposition, and ameliorates cognitive deficits in an Alzheimer's disease mouse model.
    Ribeiro CA; Oliveira SM; Guido LF; Magalhães A; Valencia G; Arsequell G; Saraiva MJ; Cardoso I
    J Alzheimers Dis; 2014; 39(2):357-70. PubMed ID: 24169237
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Insights on the Interaction between Transthyretin and Aβ in Solution. A Saturation Transfer Difference (STD) NMR Analysis of the Role of Iododiflunisal.
    Gimeno A; Santos LM; Alemi M; Rivas J; Blasi D; Cotrina EY; Llop J; Valencia G; Cardoso I; Quintana J; Arsequell G; Jiménez-Barbero J
    J Med Chem; 2017 Jul; 60(13):5749-5758. PubMed ID: 28587455
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Transthyretin stability is critical in assisting beta amyloid clearance- Relevance of transthyretin stabilization in Alzheimer's disease.
    Alemi M; Silva SC; Santana I; Cardoso I
    CNS Neurosci Ther; 2017 Jul; 23(7):605-619. PubMed ID: 28570028
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Oral Treatment with Iododiflunisal Delays Hippocampal Amyloid-β Formation in a Transgenic Mouse Model of Alzheimer's Disease: A Longitudinal in vivo Molecular Imaging Study1.
    Rejc L; Gómez-Vallejo V; Rios X; Cossío U; Baz Z; Mujica E; Gião T; Cotrina EY; Jiménez-Barbero J; Quintana J; Arsequell G; Cardoso I; Llop J
    J Alzheimers Dis; 2020; 77(1):99-112. PubMed ID: 32804152
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Radiochemical examination of transthyretin (TTR) brain penetration assisted by iododiflunisal, a TTR tetramer stabilizer and a new candidate drug for AD.
    Rios X; Gómez-Vallejo V; Martín A; Cossío U; Morcillo MÁ; Alemi M; Cardoso I; Quintana J; Jiménez-Barbero J; Cotrina EY; Valencia G; Arsequell G; Llop J
    Sci Rep; 2019 Sep; 9(1):13672. PubMed ID: 31541162
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The inhibition of cellular toxicity of amyloid-β by dissociated transthyretin.
    Cao Q; Anderson DH; Liang WY; Chou J; Saelices L
    J Biol Chem; 2020 Oct; 295(41):14015-14024. PubMed ID: 32769117
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis and PET Imaging Biodistribution Studies of Radiolabeled Iododiflunisal, a Transthyretin Tetramer Stabilizer, Candidate Drug for Alzheimer's Disease.
    Joshi SM; Wilson TC; Li Z; Preshlock S; Gómez-Vallejo V; Gouverneur V; Llop J; Arsequell G
    Molecules; 2024 Jan; 29(2):. PubMed ID: 38257401
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Copper mediated amyloid-β binding to Transthyretin.
    Ciccone L; Fruchart-Gaillard C; Mourier G; Savko M; Nencetti S; Orlandini E; Servent D; Stura EA; Shepard W
    Sci Rep; 2018 Sep; 8(1):13744. PubMed ID: 30213975
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Transthyretin variants with improved inhibition of β-amyloid aggregation.
    Mangrolia P; Yang DT; Murphy RM
    Protein Eng Des Sel; 2016 Jun; 29(6):209-218. PubMed ID: 27099354
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Retinol-Binding Protein Interferes with Transthyretin-Mediated β-Amyloid Aggregation Inhibition.
    Mangrolia P; Murphy RM
    Biochemistry; 2018 Aug; 57(33):5029-5040. PubMed ID: 30024734
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mechanisms of transthyretin inhibition of β-amyloid aggregation in vitro.
    Li X; Zhang X; Ladiwala AR; Du D; Yadav JK; Tessier PM; Wright PE; Kelly JW; Buxbaum JN
    J Neurosci; 2013 Dec; 33(50):19423-33. PubMed ID: 24336709
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A Cyclic Peptide Mimic of the β-Amyloid Binding Domain on Transthyretin.
    Cho PY; Joshi G; Boersma MD; Johnson JA; Murphy RM
    ACS Chem Neurosci; 2015 May; 6(5):778-89. PubMed ID: 25713928
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Characterization of the interaction of β-amyloid with transthyretin monomers and tetramers.
    Du J; Murphy RM
    Biochemistry; 2010 Sep; 49(38):8276-89. PubMed ID: 20795734
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The Function of Transthyretin Complexes with Metallothionein in Alzheimer's Disease.
    Zaręba N; Kepinska M
    Int J Mol Sci; 2020 Nov; 21(23):. PubMed ID: 33256250
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Gd-nanoparticles functionalization with specific peptides for ß-amyloid plaques targeting.
    Plissonneau M; Pansieri J; Heinrich-Balard L; Morfin JF; Stransky-Heilkron N; Rivory P; Mowat P; Dumoulin M; Cohen R; Allémann É; Tόth É; Saraiva MJ; Louis C; Tillement O; Forge V; Lux F; Marquette C
    J Nanobiotechnology; 2016 Jul; 14(1):60. PubMed ID: 27455834
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Accelerated Abeta deposition in APPswe/PS1deltaE9 mice with hemizygous deletions of TTR (transthyretin).
    Choi SH; Leight SN; Lee VM; Li T; Wong PC; Johnson JA; Saraiva MJ; Sisodia SS
    J Neurosci; 2007 Jun; 27(26):7006-10. PubMed ID: 17596449
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Neuroprotection in early stages of Alzheimer's disease is promoted by transthyretin angiogenic properties.
    Gião T; Saavedra J; Vieira JR; Pinto MT; Arsequell G; Cardoso I
    Alzheimers Res Ther; 2021 Aug; 13(1):143. PubMed ID: 34429155
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.