BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

112 related articles for article (PubMed ID: 32762073)

  • 1. Activating Effect of 3-Benzylidene Oxindoles on AMPK: From Computer Simulation to High-Content Screening.
    Novikova DS; Grigoreva TA; Ivanov GS; Melino G; Barlev NA; Tribulovich VG
    ChemMedChem; 2020 Dec; 15(24):2521-2529. PubMed ID: 32762073
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Substituted oxindol-3-ylidenes as AMP-activated protein kinase (AMPK) inhibitors.
    Matheson CJ; Casalvieri KA; Backos DS; Minhajuddin M; Jordan CT; Reigan P
    Eur J Med Chem; 2020 Jul; 197():112316. PubMed ID: 32334266
    [TBL] [Abstract][Full Text] [Related]  

  • 3. In silico Analysis of AMP-activated Protein Kinase and Ligand-based Virtual Screening for Identification of Novel AMPK Activators.
    Ghaffar A; Batool S; Mushtaq G; Kamal MA
    Curr Comput Aided Drug Des; 2017; 13(3):222-233. PubMed ID: 28294049
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mechanism of action of compound-13: an α1-selective small molecule activator of AMPK.
    Hunter RW; Foretz M; Bultot L; Fullerton MD; Deak M; Ross FA; Hawley SA; Shpiro N; Viollet B; Barron D; Kemp BE; Steinberg GR; Hardie DG; Sakamoto K
    Chem Biol; 2014 Jul; 21(7):866-79. PubMed ID: 25036776
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Design, synthesis and biological evaluation of mogrol derivatives as a novel class of AMPKα2β1γ1 activators.
    Wang J; Liu J; Xie Z; Li J; Li J; Hu L
    Bioorg Med Chem Lett; 2020 Jan; 30(2):126790. PubMed ID: 31744674
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structures of AMP-activated protein kinase bound to novel pharmacological activators in phosphorylated, non-phosphorylated, and nucleotide-free states.
    Yan Y; Zhou XE; Novick SJ; Shaw SJ; Li Y; Brunzelle JS; Hitoshi Y; Griffin PR; Xu HE; Melcher K
    J Biol Chem; 2019 Jan; 294(3):953-967. PubMed ID: 30478170
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Recent progress in the identification of adenosine monophosphate-activated protein kinase (AMPK) activators.
    Cameron KO; Kurumbail RG
    Bioorg Med Chem Lett; 2016 Nov; 26(21):5139-5148. PubMed ID: 27727125
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Identification of Direct Activator of Adenosine Monophosphate-Activated Protein Kinase (AMPK) by Structure-Based Virtual Screening and Molecular Docking Approach.
    Huang T; Sun J; Zhou S; Gao J; Liu Y
    Int J Mol Sci; 2017 Jun; 18(7):. PubMed ID: 28665353
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Identification of a novel 2-oxindole fluorinated derivative as in vivo antitumor agent for prostate cancer acting via AMPK activation.
    Bort A; Quesada S; Ramos-Torres Á; Gargantilla M; Priego EM; Raynal S; Lepifre F; Gasalla JM; Rodriguez-Henche N; Castro A; Díaz-Laviada I
    Sci Rep; 2018 Mar; 8(1):4370. PubMed ID: 29531259
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structural basis of allosteric and synergistic activation of AMPK by furan-2-phosphonic derivative C2 binding.
    Langendorf CG; Ngoei KRW; Scott JW; Ling NXY; Issa SMA; Gorman MA; Parker MW; Sakamoto K; Oakhill JS; Kemp BE
    Nat Commun; 2016 Mar; 7():10912. PubMed ID: 26952388
    [TBL] [Abstract][Full Text] [Related]  

  • 11. AMP-activated protein kinase: the current landscape for drug development.
    Steinberg GR; Carling D
    Nat Rev Drug Discov; 2019 Jul; 18(7):527-551. PubMed ID: 30867601
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Discovery of natural adenosine monophosphate‑activated protein kinase activators through virtual screening and activity verification studies.
    Hao J; Yang Z; Li J; Han L; Zhang Y; Wang T
    Mol Med Rep; 2021 Mar; 23(3):. PubMed ID: 33495803
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Polyphyllin I activates AMPK to suppress the growth of non-small-cell lung cancer via induction of autophagy.
    Wu Y; Si Y; Xiang Y; Zhou T; Liu X; Wu M; Li W; Zhang T; Xiang K; Zhang L; Zhao H; Liu Y
    Arch Biochem Biophys; 2020 Jul; 687():108285. PubMed ID: 32074500
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Identification of potential AMPK activator by pharmacophore modeling, molecular docking and QSAR study.
    Li Y; Peng J; Li P; Du H; Li Y; Liu X; Zhang L; Wang LL; Zuo Z
    Comput Biol Chem; 2019 Apr; 79():165-176. PubMed ID: 30836318
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Development of Potent Adenosine Monophosphate Activated Protein Kinase (AMPK) Activators.
    Dokla EM; Fang CS; Lai PT; Kulp SK; Serya RA; Ismail NS; Abouzid KA; Chen CS
    ChemMedChem; 2015 Nov; 10(11):1915-23. PubMed ID: 26350292
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Discovery, synthesis, and structure-activity relationships of 20(S)-protopanaxadiol (PPD) derivatives as a novel class of AMPKα2β1γ1 activators.
    Liu J; Chen D; Liu P; He M; Li J; Li J; Hu L
    Eur J Med Chem; 2014 May; 79():340-9. PubMed ID: 24747289
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Natural activators of adenosine 5'-monophosphate (AMP)-activated protein kinase (AMPK) and their pharmacological activities.
    Vazirian M; Nabavi SM; Jafari S; Manayi A
    Food Chem Toxicol; 2018 Dec; 122():69-79. PubMed ID: 30290216
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Traumatic brain injury decreases AMP-activated protein kinase activity and pharmacological enhancement of its activity improves cognitive outcome.
    Hill JL; Kobori N; Zhao J; Rozas NS; Hylin MJ; Moore AN; Dash PK
    J Neurochem; 2016 Oct; 139(1):106-19. PubMed ID: 27379837
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structural Determinants for Small-Molecule Activation of Skeletal Muscle AMPK α2β2γ1 by the Glucose Importagog SC4.
    Ngoei KRW; Langendorf CG; Ling NXY; Hoque A; Varghese S; Camerino MA; Walker SR; Bozikis YE; Dite TA; Ovens AJ; Smiles WJ; Jacobs R; Huang H; Parker MW; Scott JW; Rider MH; Foitzik RC; Kemp BE; Baell JB; Oakhill JS
    Cell Chem Biol; 2018 Jun; 25(6):728-737.e9. PubMed ID: 29657085
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Probing the enzyme kinetics, allosteric modulation and activation of α1- and α2-subunit-containing AMP-activated protein kinase (AMPK) heterotrimeric complexes by pharmacological and physiological activators.
    Rajamohan F; Reyes AR; Frisbie RK; Hoth LR; Sahasrabudhe P; Magyar R; Landro JA; Withka JM; Caspers NL; Calabrese MF; Ward J; Kurumbail RG
    Biochem J; 2016 Mar; 473(5):581-92. PubMed ID: 26635351
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.