200 related articles for article (PubMed ID: 32763910)
1. miR760 regulates ATXN1 levels via interaction with its 5' untranslated region.
Nitschke L; Tewari A; Coffin SL; Xhako E; Pang K; Gennarino VA; Johnson JL; Blanco FA; Liu Z; Zoghbi HY
Genes Dev; 2020 Sep; 34(17-18):1147-1160. PubMed ID: 32763910
[TBL] [Abstract][Full Text] [Related]
2. UTteR control through miRs: fine-tuning ATXN1 levels to prevent ataxia.
Xie M; Swanson MS
Genes Dev; 2020 Sep; 34(17-18):1107-1109. PubMed ID: 32873576
[TBL] [Abstract][Full Text] [Related]
3. 5'UTR-mediated regulation of Ataxin-1 expression.
Manek R; Nelson T; Tseng E; Rodriguez-Lebron E
Neurobiol Dis; 2020 Feb; 134():104564. PubMed ID: 31381977
[TBL] [Abstract][Full Text] [Related]
4. Ataxin-1 regulates the cerebellar bioenergetics proteome through the GSK3β-mTOR pathway which is altered in Spinocerebellar ataxia type 1 (SCA1).
Sánchez I; Balagué E; Matilla-Dueñas A
Hum Mol Genet; 2016 Sep; 25(18):4021-4040. PubMed ID: 27466200
[TBL] [Abstract][Full Text] [Related]
5. Inhibition of colony-stimulating factor 1 receptor early in disease ameliorates motor deficits in SCA1 mice.
Qu W; Johnson A; Kim JH; Lukowicz A; Svedberg D; Cvetanovic M
J Neuroinflammation; 2017 May; 14(1):107. PubMed ID: 28545543
[TBL] [Abstract][Full Text] [Related]
6. PAK1 regulates ATXN1 levels providing an opportunity to modify its toxicity in spinocerebellar ataxia type 1.
Bondar VV; Adamski CJ; Onur TS; Tan Q; Wang L; Diaz-Garcia J; Park J; Orr HT; Botas J; Zoghbi HY
Hum Mol Genet; 2018 Aug; 27(16):2863-2873. PubMed ID: 29860311
[TBL] [Abstract][Full Text] [Related]
7. Partial loss of ataxin-1 function contributes to transcriptional dysregulation in spinocerebellar ataxia type 1 pathogenesis.
Crespo-Barreto J; Fryer JD; Shaw CA; Orr HT; Zoghbi HY
PLoS Genet; 2010 Jul; 6(7):e1001021. PubMed ID: 20628574
[TBL] [Abstract][Full Text] [Related]
8. Modulation of ATXN1 S776 phosphorylation reveals the importance of allele-specific targeting in SCA1.
Nitschke L; Coffin SL; Xhako E; El-Najjar DB; Orengo JP; Alcala E; Dai Y; Wan YW; Liu Z; Orr HT; Zoghbi HY
JCI Insight; 2021 Feb; 6(3):. PubMed ID: 33554954
[TBL] [Abstract][Full Text] [Related]
9. Ataxin-1 regulates proliferation of hippocampal neural precursors.
Asher M; Johnson A; Zecevic B; Pease D; Cvetanovic M
Neuroscience; 2016 May; 322():54-65. PubMed ID: 26876606
[TBL] [Abstract][Full Text] [Related]
10. Cerebellar contribution to the cognitive alterations in SCA1: evidence from mouse models.
Asher M; Rosa JG; Rainwater O; Duvick L; Bennyworth M; Lai RY; ; Kuo SH; Cvetanovic M
Hum Mol Genet; 2020 Jan; 29(1):117-131. PubMed ID: 31696233
[TBL] [Abstract][Full Text] [Related]
11. Regional rescue of spinocerebellar ataxia type 1 phenotypes by 14-3-3epsilon haploinsufficiency in mice underscores complex pathogenicity in neurodegeneration.
Jafar-Nejad P; Ward CS; Richman R; Orr HT; Zoghbi HY
Proc Natl Acad Sci U S A; 2011 Feb; 108(5):2142-7. PubMed ID: 21245341
[TBL] [Abstract][Full Text] [Related]
12. Spinocerebellar Ataxia Type 1: Molecular Mechanisms of Neurodegeneration and Preclinical Studies.
Pérez Ortiz JM; Orr HT
Adv Exp Med Biol; 2018; 1049():135-145. PubMed ID: 29427101
[TBL] [Abstract][Full Text] [Related]
13. Dual targeting of brain region-specific kinases potentiates neurological rescue in Spinocerebellar ataxia type 1.
Lee WS; Lavery L; Rousseaux MWC; Rutledge EB; Jang Y; Wan YW; Wu SR; Kim W; Al-Ramahi I; Rath S; Adamski CJ; Bondar VV; Tewari A; Soleimani S; Mota S; Yalamanchili HK; Orr HT; Liu Z; Botas J; Zoghbi HY
EMBO J; 2021 Apr; 40(7):e106106. PubMed ID: 33709453
[TBL] [Abstract][Full Text] [Related]
14. Indirect Negative Effect of Mutant Ataxin-1 on Short- and Long-Term Synaptic Plasticity in Mouse Models of Spinocerebellar Ataxia Type 1.
Shuvaev AN; Belozor OS; Mozhei OI; Shuvaev AN; Fritsler YV; Khilazheva ED; Mosyagina AI; Hirai H; Teschemacher AG; Kasparov S
Cells; 2022 Jul; 11(14):. PubMed ID: 35883691
[TBL] [Abstract][Full Text] [Related]
15. Decreasing mutant ATXN1 nuclear localization improves a spectrum of SCA1-like phenotypes and brain region transcriptomic profiles.
Handler HP; Duvick L; Mitchell JS; Cvetanovic M; Reighard M; Soles A; Mather KB; Rainwater O; Serres S; Nichols-Meade T; Coffin SL; You Y; Ruis BL; O'Callaghan B; Henzler C; Zoghbi HY; Orr HT
Neuron; 2023 Feb; 111(4):493-507.e6. PubMed ID: 36577403
[TBL] [Abstract][Full Text] [Related]
16. BDNF is altered in a brain-region specific manner and rescues deficits in Spinocerebellar Ataxia Type 1.
Rosa JG; Hamel K; Soles A; Sheeler C; Borgenheimer E; Gilliat S; Sbrocco K; Ghanoum F; Handler HP; Forster C; Rainwater O; Cvetanovic M
Neurobiol Dis; 2023 Mar; 178():106023. PubMed ID: 36724861
[TBL] [Abstract][Full Text] [Related]
17. Sphingolipid metabolism governs Purkinje cell patterned degeneration in
Blot FGC; Krijnen WHJJ; Den Hoedt S; Osório C; White JJ; Mulder MT; Schonewille M
Proc Natl Acad Sci U S A; 2021 Sep; 118(36):. PubMed ID: 34479994
[TBL] [Abstract][Full Text] [Related]
18. ATXN1-CIC Complex Is the Primary Driver of Cerebellar Pathology in Spinocerebellar Ataxia Type 1 through a Gain-of-Function Mechanism.
Rousseaux MWC; Tschumperlin T; Lu HC; Lackey EP; Bondar VV; Wan YW; Tan Q; Adamski CJ; Friedrich J; Twaroski K; Chen W; Tolar J; Henzler C; Sharma A; Bajić A; Lin T; Duvick L; Liu Z; Sillitoe RV; Zoghbi HY; Orr HT
Neuron; 2018 Mar; 97(6):1235-1243.e5. PubMed ID: 29526553
[TBL] [Abstract][Full Text] [Related]
19. Therapeutic Strategies for Spinocerebellar Ataxia Type 1.
Kerkhof LMC; van de Warrenburg BPC; van Roon-Mom WMC; Buijsen RAM
Biomolecules; 2023 May; 13(5):. PubMed ID: 37238658
[TBL] [Abstract][Full Text] [Related]
20. Disruption of the ATXN1-CIC complex reveals the role of additional nuclear ATXN1 interactors in spinocerebellar ataxia type 1.
Coffin SL; Durham MA; Nitschke L; Xhako E; Brown AM; Revelli JP; Villavicencio Gonzalez E; Lin T; Handler HP; Dai Y; Trostle AJ; Wan YW; Liu Z; Sillitoe RV; Orr HT; Zoghbi HY
Neuron; 2023 Feb; 111(4):481-492.e8. PubMed ID: 36577402
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]