257 related articles for article (PubMed ID: 32764664)
1. The natural function of the malaria parasite's chloroquine resistance transporter.
Shafik SH; Cobbold SA; Barkat K; Richards SN; Lancaster NS; Llinás M; Hogg SJ; Summers RL; McConville MJ; Martin RE
Nat Commun; 2020 Aug; 11(1):3922. PubMed ID: 32764664
[TBL] [Abstract][Full Text] [Related]
2. Chloroquine transport via the malaria parasite's chloroquine resistance transporter.
Martin RE; Marchetti RV; Cowan AI; Howitt SM; Bröer S; Kirk K
Science; 2009 Sep; 325(5948):1680-2. PubMed ID: 19779197
[TBL] [Abstract][Full Text] [Related]
3. A 2-amino quinoline, 5-(3-(2-(7-chloroquinolin-2-yl)ethenyl)phenyl)-8-dimethylcarbamyl-4,6-dithiaoctanoic acid, interacts with PfMDR1 and inhibits its drug transport in Plasmodium falciparum.
Edaye S; Reiling SJ; Leimanis ML; Wunderlich J; Rohrbach P; Georges E
Mol Biochem Parasitol; 2014 Jun; 195(1):34-42. PubMed ID: 24914817
[TBL] [Abstract][Full Text] [Related]
4. Functional characteristics of the malaria parasite's "chloroquine resistance transporter": implications for chemotherapy.
Summers RL; Martin RE
Virulence; 2010; 1(4):304-8. PubMed ID: 21178460
[TBL] [Abstract][Full Text] [Related]
5. Molecular Mechanisms for Drug Hypersensitivity Induced by the Malaria Parasite's Chloroquine Resistance Transporter.
Richards SN; Nash MN; Baker ES; Webster MW; Lehane AM; Shafik SH; Martin RE
PLoS Pathog; 2016 Jul; 12(7):e1005725. PubMed ID: 27441371
[TBL] [Abstract][Full Text] [Related]
6. Chloroquine resistance-conferring mutations in pfcrt give rise to a chloroquine-associated H+ leak from the malaria parasite's digestive vacuole.
Lehane AM; Kirk K
Antimicrob Agents Chemother; 2008 Dec; 52(12):4374-80. PubMed ID: 18852275
[TBL] [Abstract][Full Text] [Related]
7. Verapamil-Sensitive Transport of Quinacrine and Methylene Blue via the Plasmodium falciparum Chloroquine Resistance Transporter Reduces the Parasite's Susceptibility to these Tricyclic Drugs.
van Schalkwyk DA; Nash MN; Shafik SH; Summers RL; Lehane AM; Smith PJ; Martin RE
J Infect Dis; 2016 Mar; 213(5):800-10. PubMed ID: 26503982
[TBL] [Abstract][Full Text] [Related]
8. Mechanistic basis for multidrug resistance and collateral drug sensitivity conferred to the malaria parasite by polymorphisms in PfMDR1 and PfCRT.
Shafik SH; Richards SN; Corry B; Martin RE
PLoS Biol; 2022 May; 20(5):e3001616. PubMed ID: 35507548
[TBL] [Abstract][Full Text] [Related]
9. Efflux of a range of antimalarial drugs and 'chloroquine resistance reversers' from the digestive vacuole in malaria parasites with mutant PfCRT.
Lehane AM; Kirk K
Mol Microbiol; 2010 Aug; 77(4):1039-51. PubMed ID: 20598081
[TBL] [Abstract][Full Text] [Related]
10. The Knock-Down of the Chloroquine Resistance Transporter PfCRT Is Linked to Oligopeptide Handling in Plasmodium falciparum.
Sanchez CP; Manson EDT; Moliner Cubel S; Mandel L; Weidt SK; Barrett MP; Lanzer M
Microbiol Spectr; 2022 Aug; 10(4):e0110122. PubMed ID: 35867395
[TBL] [Abstract][Full Text] [Related]
11. Mutations in the Plasmodium falciparum chloroquine resistance transporter, PfCRT, enlarge the parasite's food vacuole and alter drug sensitivities.
Pulcini S; Staines HM; Lee AH; Shafik SH; Bouyer G; Moore CM; Daley DA; Hoke MJ; Altenhofen LM; Painter HJ; Mu J; Ferguson DJ; Llinás M; Martin RE; Fidock DA; Cooper RA; Krishna S
Sci Rep; 2015 Sep; 5():14552. PubMed ID: 26420308
[TBL] [Abstract][Full Text] [Related]
12. Quinine dimers are potent inhibitors of the Plasmodium falciparum chloroquine resistance transporter and are active against quinoline-resistant P. falciparum.
Hrycyna CA; Summers RL; Lehane AM; Pires MM; Namanja H; Bohn K; Kuriakose J; Ferdig M; Henrich PP; Fidock DA; Kirk K; Chmielewski J; Martin RE
ACS Chem Biol; 2014 Mar; 9(3):722-30. PubMed ID: 24369685
[TBL] [Abstract][Full Text] [Related]
13. PfCRT and its role in antimalarial drug resistance.
Ecker A; Lehane AM; Clain J; Fidock DA
Trends Parasitol; 2012 Nov; 28(11):504-14. PubMed ID: 23020971
[TBL] [Abstract][Full Text] [Related]
14. Diverse mutational pathways converge on saturable chloroquine transport via the malaria parasite's chloroquine resistance transporter.
Summers RL; Dave A; Dolstra TJ; Bellanca S; Marchetti RV; Nash MN; Richards SN; Goh V; Schenk RL; Stein WD; Kirk K; Sanchez CP; Lanzer M; Martin RE
Proc Natl Acad Sci U S A; 2014 Apr; 111(17):E1759-67. PubMed ID: 24728833
[TBL] [Abstract][Full Text] [Related]
15. A Redox-Active Fluorescent pH Indicator for Detecting Plasmodium falciparum Strains with Reduced Responsiveness to Quinoline Antimalarial Drugs.
Jida M; Sanchez CP; Urgin K; Ehrhardt K; Mounien S; Geyer A; Elhabiri M; Lanzer M; Davioud-Charvet E
ACS Infect Dis; 2017 Feb; 3(2):119-131. PubMed ID: 28183182
[TBL] [Abstract][Full Text] [Related]
16. Combinatorial Genetic Modeling of pfcrt-Mediated Drug Resistance Evolution in Plasmodium falciparum.
Gabryszewski SJ; Modchang C; Musset L; Chookajorn T; Fidock DA
Mol Biol Evol; 2016 Jun; 33(6):1554-70. PubMed ID: 26908582
[TBL] [Abstract][Full Text] [Related]
17. Iron is a substrate of the
Bakouh N; Bellanca S; Nyboer B; Moliner Cubel S; Karim Z; Sanchez CP; Stein WD; Planelles G; Lanzer M
J Biol Chem; 2017 Sep; 292(39):16109-16121. PubMed ID: 28768767
[TBL] [Abstract][Full Text] [Related]
18. Altered Drug Transport by
Riegel B; Roepe PD
Biochemistry; 2020 Jul; 59(27):2484-2493. PubMed ID: 32589406
[TBL] [Abstract][Full Text] [Related]
19. Saquinavir inhibits the malaria parasite's chloroquine resistance transporter.
Martin RE; Butterworth AS; Gardiner DL; Kirk K; McCarthy JS; Skinner-Adams TS
Antimicrob Agents Chemother; 2012 May; 56(5):2283-9. PubMed ID: 22354298
[TBL] [Abstract][Full Text] [Related]
20. Is PfCRT a channel or a carrier? Two competing models explaining chloroquine resistance in Plasmodium falciparum.
Sanchez CP; Stein WD; Lanzer M
Trends Parasitol; 2007 Jul; 23(7):332-9. PubMed ID: 17493873
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]