166 related articles for article (PubMed ID: 32767959)
1. Docking Studies and Antiproliferative Activities of 6-(3-aryl-2-propenoyl)-2(3H)- benzoxazolone Derivatives as Novel Inhibitors of Phosphatidylinositol 3-Kinase (PI3Kα).
Bilginer S; Bardaweel SK; Sabbah DA; Gul HI
Anticancer Agents Med Chem; 2021; 21(6):716-724. PubMed ID: 32767959
[TBL] [Abstract][Full Text] [Related]
2. Benzoin Schiff Bases: Design, Synthesis, and Biological Evaluation as Potential Antitumor Agents.
Sabbah DA; Al-Tarawneh F; Talib WH; Sweidan K; Bardaweel SK; Al-Shalabi E; Zhong HA; Abu Sheikha G; Abu Khalaf R; Mubarak MS
Med Chem; 2018; 14(7):695-708. PubMed ID: 29651943
[TBL] [Abstract][Full Text] [Related]
3. Structure-Based Design: Synthesis, X-ray Crystallography, and Biological Evaluation of N-Substituted-4-Hydroxy-2-Quinolone-3-Carboxamides as Potential Cytotoxic Agents.
Sabbah DA; Hishmah B; Sweidan K; Bardaweel S; AlDamen M; Zhong HA; Abu Khalaf R; Hasan Ibrahim A; Al-Qirim T; Abu Sheikha G; Mubarak MS
Anticancer Agents Med Chem; 2018; 18(2):263-276. PubMed ID: 28901259
[TBL] [Abstract][Full Text] [Related]
4. Ligand-Based Drug Design: Synthesis and Biological Evaluation of Substituted Benzoin Derivatives as Potential Antitumor Agents.
Sabbah DA; Ibrahim AH; Talib WH; Alqaisi KM; Sweidan K; Bardaweel SK; Sheikha GA; Zhong HA; Al-Shalabi E; Khalaf RA; Mubarak MS
Med Chem; 2019; 15(4):417-429. PubMed ID: 30207238
[TBL] [Abstract][Full Text] [Related]
5. Design, synthesis and biological evaluation of novel chromeno[4,3-c]pyrazol-4(2H)-one derivates containing sulfonamido as potential PI3Kα inhibitors.
Yin Y; Hu JQ; Wu X; Sha S; Wang SF; Qiao F; Song ZC; Zhu HL
Bioorg Med Chem; 2019 Jun; 27(11):2261-2267. PubMed ID: 31029551
[TBL] [Abstract][Full Text] [Related]
6. Design, synthesis and biological activity of novel 2,3,4,5-tetra-substituted thiophene derivatives as PI3Kα inhibitors with potent antitumor activity.
Liao W; Wang Z; Han Y; Qi Y; Liu J; Xie J; Tian Y; Lei Q; Chen R; Sun M; Tang L; Gong G; Zhao Y
Eur J Med Chem; 2020 Jul; 197():112309. PubMed ID: 32375077
[TBL] [Abstract][Full Text] [Related]
7. Development of novel chromeno[4,3-c]pyrazol-4(2H)-one derivates containing piperazine as inhibitors of PI3Kα.
Yin Y; Zhou Y; Sha S; Wu X; Wang SF; Qiao F; Song ZC; Zhu HL
Bioorg Chem; 2019 Nov; 92():103238. PubMed ID: 31499259
[TBL] [Abstract][Full Text] [Related]
8. Molecular modeling based approach, synthesis, and cytotoxic activity of novel benzoin derivatives targeting phosphoinostide 3-kinase (PI3Kα).
Sabbah DA; Saada M; Khalaf RA; Bardaweel S; Sweidan K; Al-Qirim T; Al-Zughier A; Halim HA; Sheikha GA
Bioorg Med Chem Lett; 2015 Aug; 25(16):3120-4. PubMed ID: 26099539
[TBL] [Abstract][Full Text] [Related]
9. Synthesis and anticancer evaluation of novel 1H-benzo[d]imidazole derivatives of dehydroabietic acid as PI3Kα inhibitors.
Yang YQ; Chen H; Liu QS; Sun Y; Gu W
Bioorg Chem; 2020 Jul; 100():103845. PubMed ID: 32344183
[TBL] [Abstract][Full Text] [Related]
10. Synthesis and Apoptotic Activities of New 2(3H)-benzoxazolone Derivatives in Breast Cancer Cells.
Erdag E; Becer E; Mulazim Y; Vatansever HS; Kabadayı H; Kesanli B
Anticancer Agents Med Chem; 2021; 21(1):84-90. PubMed ID: 32698749
[TBL] [Abstract][Full Text] [Related]
11. Design, synthesis, and biological evaluation of novel 6-(pyridin-3-yl) quinazolin-4(3H)-one derivatives as potential anticancer agents via PI3K inhibition.
Yang H; Li Q; Su M; Luo F; Liu Y; Wang D; Fan Y
Bioorg Med Chem; 2021 Sep; 46():116346. PubMed ID: 34403956
[TBL] [Abstract][Full Text] [Related]
12. Biological evaluation and docking studies of recently identified inhibitors of phosphoinositide-3-kinases.
Sabbah DA; Simms NA; Brattain MG; Vennerstrom JL; Zhong H
Bioorg Med Chem Lett; 2012 Jan; 22(2):876-80. PubMed ID: 22212721
[TBL] [Abstract][Full Text] [Related]
13. Novel 4-aminoquinazoline derivatives induce growth inhibition, cell cycle arrest and apoptosis via PI3Kα inhibition.
Fan YH; Ding HW; Liu DD; Song HR; Xu YN; Wang J
Bioorg Med Chem; 2018 May; 26(8):1675-1685. PubMed ID: 29475582
[TBL] [Abstract][Full Text] [Related]
14. Design, synthesis, and biological evaluation of novel 3-substituted imidazo[1,2-a]pyridine and quinazolin-4(3H)-one derivatives as PI3Kα inhibitors.
Fan YH; Li W; Liu DD; Bai MX; Song HR; Xu YN; Lee S; Zhou ZP; Wang J; Ding HW
Eur J Med Chem; 2017 Oct; 139():95-106. PubMed ID: 28800461
[TBL] [Abstract][Full Text] [Related]
15. Design, synthesis and evaluation of 2, 6, 8-substituted Imidazopyridine derivatives as potent PI3K
Chen R; Wang Z; Sima L; Cheng H; Luo B; Wang J; Guo B; Mao S; Zhou Z; Peng J; Tang L; Liu X; Liao W
J Enzyme Inhib Med Chem; 2023 Dec; 38(1):2155638. PubMed ID: 36650905
[TBL] [Abstract][Full Text] [Related]
16. Difuran-substituted quinoxalines as a novel class of PI3Kα H1047R mutant inhibitors: Synthesis, biological evaluation and structure-activity relationship.
Zhang N; Yu Z; Yang X; Zhou Y; Tang Q; Hu P; Wang J; Zhang SL; Wang MW; He Y
Eur J Med Chem; 2018 Sep; 157():37-49. PubMed ID: 30071408
[TBL] [Abstract][Full Text] [Related]
17. Development of novel chromeno[4,3-c]pyrazol-4(2H)-one derivates bearing sulfonylpiperazine as antitumor inhibitors targeting PI3Kα.
Yin Y; Sha S; Wu X; Wang SF; Qiao F; Song ZC; Zhu HL
Eur J Med Chem; 2019 Nov; 182():111630. PubMed ID: 31446244
[TBL] [Abstract][Full Text] [Related]
18. Computer-aided design, synthesis, and biological evaluation of new indole-2-carboxamide derivatives as PI3Kα/EGFR inhibitors.
Sweidan K; Sabbah DA; Bardaweel S; Dush KA; Sheikha GA; Mubarak MS
Bioorg Med Chem Lett; 2016 Jun; 26(11):2685-90. PubMed ID: 27084677
[TBL] [Abstract][Full Text] [Related]
19. Design, synthesis and evaluation of some 1,6-disubstituted-1H-benzo[d]imidazoles derivatives targeted PI3K as anticancer agents.
Ding HW; Yu L; Bai MX; Qin XC; Song MT; Zhao QC
Bioorg Chem; 2019 Dec; 93():103283. PubMed ID: 31585260
[TBL] [Abstract][Full Text] [Related]
20. Design, synthesis, antitumor activity and theoretical calculation of novel PI3Ka inhibitors.
Jin RY; Tang T; Zhou S; Long X; Guo H; Zhou J; Yan H; Li Z; Zuo ZY; Xie HL; Tang YP
Bioorg Chem; 2020 May; 98():103737. PubMed ID: 32193031
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]