BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

157 related articles for article (PubMed ID: 32768438)

  • 21. Impact of loss of BH3-only proteins on the development and treatment of MLL-fusion gene-driven AML in mice.
    Bilardi RA; Anstee NS; Glaser SP; Robati M; Vandenberg CJ; Cory S
    Cell Death Dis; 2016 Sep; 7(9):e2351. PubMed ID: 27584789
    [TBL] [Abstract][Full Text] [Related]  

  • 22. MLL-AF9 and MLL-AF4 oncofusion proteins bind a distinct enhancer repertoire and target the RUNX1 program in 11q23 acute myeloid leukemia.
    Prange KHM; Mandoli A; Kuznetsova T; Wang SY; Sotoca AM; Marneth AE; van der Reijden BA; Stunnenberg HG; Martens JHA
    Oncogene; 2017 Jun; 36(23):3346-3356. PubMed ID: 28114278
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Development of embryonic and adult leukemia mouse models driven by MLL-ENL translocation.
    Sinha R; Porcheri C; d'Altri T; González J; Ruiz-Herguido C; Rabbitts T; Espinosa L; Bigas A
    Exp Hematol; 2020 May; 85():13-19. PubMed ID: 32437911
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Requirement for CDK6 in MLL-rearranged acute myeloid leukemia.
    Placke T; Faber K; Nonami A; Putwain SL; Salih HR; Heidel FH; Krämer A; Root DE; Barbie DA; Krivtsov AV; Armstrong SA; Hahn WC; Huntly BJ; Sykes SM; Milsom MD; Scholl C; Fröhling S
    Blood; 2014 Jul; 124(1):13-23. PubMed ID: 24764564
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Id2 and E Proteins Orchestrate the Initiation and Maintenance of MLL-Rearranged Acute Myeloid Leukemia.
    Ghisi M; Kats L; Masson F; Li J; Kratina T; Vidacs E; Gilan O; Doyle MA; Newbold A; Bolden JE; Fairfax KA; de Graaf CA; Firth M; Zuber J; Dickins RA; Corcoran LM; Dawson MA; Belz GT; Johnstone RW
    Cancer Cell; 2016 Jul; 30(1):59-74. PubMed ID: 27374225
    [TBL] [Abstract][Full Text] [Related]  

  • 26. MLL-AF9-mediated immortalization of human hematopoietic cells along different lineages changes during ontogeny.
    Horton SJ; Jaques J; Woolthuis C; van Dijk J; Mesuraca M; Huls G; Morrone G; Vellenga E; Schuringa JJ
    Leukemia; 2013 Apr; 27(5):1116-26. PubMed ID: 23178754
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Absence of the Shb gene in mixed-lineage leukemia MLL-AF9 cells increases latency in mice despite higher proliferation rates in vitro.
    Jamalpour M; Bergquist E; Welsh M
    Exp Cell Res; 2020 Dec; 397(2):112368. PubMed ID: 33220260
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Smyd2 is a Myc-regulated gene critical for MLL-AF9 induced leukemogenesis.
    Bagislar S; Sabò A; Kress TR; Doni M; Nicoli P; Campaner S; Amati B
    Oncotarget; 2016 Oct; 7(41):66398-66415. PubMed ID: 27655694
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Infantile mixed phenotype acute leukemia (bilineal and biphenotypic) with t(10;11)(p12;q23);MLL-MLLT10.
    Lou Z; Zhang CC; Tirado CA; Slone T; Zheng J; Zaremba CM; Oliver D; Chen W
    Leuk Res; 2010 Aug; 34(8):1107-9. PubMed ID: 20299091
    [TBL] [Abstract][Full Text] [Related]  

  • 30. NK cells play a significant role in immunosurveillance at the early stage of MLL-AF9 acute myeloid leukemia via CD226/CD155 interactions.
    Wang Y; Chen C; Dong F; Ma S; Xu J; Gong Y; Cheng H; Zhou Y; Cheng T; Hao S
    Sci China Life Sci; 2015 Dec; 58(12):1288-98. PubMed ID: 26588911
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Hematopoietic transformation in the absence of MLL1/KMT2A: distinctions in target gene reactivation.
    Chen Y; Ernst P
    Cell Cycle; 2019 Jul; 18(14):1525-1531. PubMed ID: 31161857
    [TBL] [Abstract][Full Text] [Related]  

  • 32. ZNF521 sustains the differentiation block in MLL-rearranged acute myeloid leukemia.
    Germano G; Morello G; Aveic S; Pinazza M; Minuzzo S; Frasson C; Persano L; Bonvini P; Viola G; Bresolin S; Tregnago C; Paganin M; Pigazzi M; Indraccolo S; Basso G
    Oncotarget; 2017 Apr; 8(16):26129-26141. PubMed ID: 28412727
    [TBL] [Abstract][Full Text] [Related]  

  • 33. [Establishment of AML Mouse Model by Transplantation of Hematopoietic Cells from MLL-AF9 Transgenic Mice].
    Long WY; Shen X; Xing S; Xiong GL; Wang HG; Yu ZY
    Zhongguo Shi Yan Xue Ye Xue Za Zhi; 2021 Oct; 29(5):1369-1374. PubMed ID: 34627412
    [TBL] [Abstract][Full Text] [Related]  

  • 34. The CDK9 Inhibitor Dinaciclib Exerts Potent Apoptotic and Antitumor Effects in Preclinical Models of MLL-Rearranged Acute Myeloid Leukemia.
    Baker A; Gregory GP; Verbrugge I; Kats L; Hilton JJ; Vidacs E; Lee EM; Lock RB; Zuber J; Shortt J; Johnstone RW
    Cancer Res; 2016 Mar; 76(5):1158-69. PubMed ID: 26627013
    [TBL] [Abstract][Full Text] [Related]  

  • 35. MLL-AF9 Expression in Hematopoietic Stem Cells Drives a Highly Invasive AML Expressing EMT-Related Genes Linked to Poor Outcome.
    Stavropoulou V; Kaspar S; Brault L; Sanders MA; Juge S; Morettini S; Tzankov A; Iacovino M; Lau IJ; Milne TA; Royo H; Kyba M; Valk PJM; Peters AHFM; Schwaller J
    Cancer Cell; 2016 Jul; 30(1):43-58. PubMed ID: 27344946
    [TBL] [Abstract][Full Text] [Related]  

  • 36. A murine Mll-AF4 knock-in model results in lymphoid and myeloid deregulation and hematologic malignancy.
    Chen W; Li Q; Hudson WA; Kumar A; Kirchhof N; Kersey JH
    Blood; 2006 Jul; 108(2):669-77. PubMed ID: 16551973
    [TBL] [Abstract][Full Text] [Related]  

  • 37. RAS oncogene suppression induces apoptosis followed by more differentiated and less myelosuppressive disease upon relapse of acute myeloid leukemia.
    Kim WI; Matise I; Diers MD; Largaespada DA
    Blood; 2009 Jan; 113(5):1086-96. PubMed ID: 18952898
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Identification of complex genomic breakpoint junctions in the t(9;11) MLL-AF9 fusion gene in acute leukemia.
    Super HG; Strissel PL; Sobulo OM; Burian D; Reshmi SC; Roe B; Zeleznik-Le NJ; Diaz MO; Rowley JD
    Genes Chromosomes Cancer; 1997 Oct; 20(2):185-95. PubMed ID: 9331569
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Inhibition of Rac GTPase signaling and downstream prosurvival Bcl-2 proteins as combination targeted therapy in MLL-AF9 leukemia.
    Mizukawa B; Wei J; Shrestha M; Wunderlich M; Chou FS; Griesinger A; Harris CE; Kumar AR; Zheng Y; Williams DA; Mulloy JC
    Blood; 2011 Nov; 118(19):5235-45. PubMed ID: 21940819
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Mutated Ptpn11 alters leukemic stem cell frequency and reduces the sensitivity of acute myeloid leukemia cells to Mcl1 inhibition.
    Chen L; Chen W; Mysliwski M; Serio J; Ropa J; Abulwerdi FA; Chan RJ; Patel JP; Tallman MS; Paietta E; Melnick A; Levine RL; Abdel-Wahab O; Nikolovska-Coleska Z; Muntean AG
    Leukemia; 2015 Jun; 29(6):1290-300. PubMed ID: 25650089
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 8.