These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

290 related articles for article (PubMed ID: 32781250)

  • 1. The STING-IRF3 pathway is involved in lipotoxic injury of pancreatic β cells in type 2 diabetes.
    Hu HQ; Qiao JT; Liu FQ; Wang JB; Sha S; He Q; Cui C; Song J; Zang N; Wang LS; Sun Z; Chen L; Hou XG
    Mol Cell Endocrinol; 2020 Dec; 518():110890. PubMed ID: 32781250
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Fibroblast growth factor 21 protects against lipotoxicity-induced pancreatic β-cell dysfunction via regulation of AMPK signaling and lipid metabolism.
    Xie T; So WY; Li XY; Leung PS
    Clin Sci (Lond); 2019 Oct; 133(19):2029-2044. PubMed ID: 31654570
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Activation of the STING-IRF3 pathway promotes hepatocyte inflammation, apoptosis and induces metabolic disorders in nonalcoholic fatty liver disease.
    Qiao JT; Cui C; Qing L; Wang LS; He TY; Yan F; Liu FQ; Shen YH; Hou XG; Chen L
    Metabolism; 2018 Apr; 81():13-24. PubMed ID: 29106945
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Experimental Type 2 diabetes and lipotoxicity-associated neuroinflammation involve mitochondrial DNA-mediated cGAS/STING axis: implication of Type-1 interferon response in cognitive impairment.
    Preeti K; Sood A; Fernandes V; Khan I; Khatri DK; Singh SB
    Mol Neurobiol; 2024 Sep; 61(9):6217-6244. PubMed ID: 38285288
    [TBL] [Abstract][Full Text] [Related]  

  • 5. STING-IRF3 Triggers Endothelial Inflammation in Response to Free Fatty Acid-Induced Mitochondrial Damage in Diet-Induced Obesity.
    Mao Y; Luo W; Zhang L; Wu W; Yuan L; Xu H; Song J; Fujiwara K; Abe JI; LeMaire SA; Wang XL; Shen YH
    Arterioscler Thromb Vasc Biol; 2017 May; 37(5):920-929. PubMed ID: 28302626
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Activation of the STING-IRF3 pathway involved in psoriasis with diabetes mellitus.
    Xiaohong L; Zhenting Z; Yunjie Y; Wei C; Xiangjin X; Kun X; Xin L; Lu L; Jun L; Pin C
    J Cell Mol Med; 2022 Apr; 26(8):2139-2151. PubMed ID: 35174638
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Palmitic acid-induced lipotoxicity promotes a novel interplay between Akt-mTOR, IRS-1, and FFAR1 signaling in pancreatic β-cells.
    Marafie SK; Al-Shawaf EM; Abubaker J; Arefanian H
    Biol Res; 2019 Aug; 52(1):44. PubMed ID: 31426858
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Palmitic acid dysregulates the Hippo-YAP pathway and inhibits angiogenesis by inducing mitochondrial damage and activating the cytosolic DNA sensor cGAS-STING-IRF3 signaling mechanism.
    Yuan L; Mao Y; Luo W; Wu W; Xu H; Wang XL; Shen YH
    J Biol Chem; 2017 Sep; 292(36):15002-15015. PubMed ID: 28698384
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Puerarin protects pancreatic β-cell survival via PI3K/Akt signaling pathway.
    Li Z; Shangguan Z; Liu Y; Wang J; Li X; Yang S; Liu S
    J Mol Endocrinol; 2014 Aug; 53(1):71-9. PubMed ID: 24827001
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Endoplasmic Reticulum Stress-induced Hepatocellular Death Pathways Mediate Liver Injury and Fibrosis via Stimulator of Interferon Genes.
    Iracheta-Vellve A; Petrasek J; Gyongyosi B; Satishchandran A; Lowe P; Kodys K; Catalano D; Calenda CD; Kurt-Jones EA; Fitzgerald KA; Szabo G
    J Biol Chem; 2016 Dec; 291(52):26794-26805. PubMed ID: 27810900
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Perilipin 5 Reduces Oxidative Damage Associated With Lipotoxicity by Activating the PI3K/ERK-Mediated Nrf2-ARE Signaling Pathway in INS-1 Pancreatic β-Cells.
    Zhu Y; Ren C; Zhang M; Zhong Y
    Front Endocrinol (Lausanne); 2020; 11():166. PubMed ID: 32296390
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Molecular analysis of db gene-related pancreatic beta cell dysfunction; evidence for a compensatory mechanism inhibiting development of diabetes in the db gene heterozygote.
    Kanda Y; Shimoda M; Tawaramoto K; Hamamoto S; Tatsumi F; Kawasaki F; Hashiramoto M; Nakashima K; Matsuki M; Kaku K
    Endocr J; 2009; 56(8):997-1008. PubMed ID: 19706988
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mst1 knockdown alleviates cardiac lipotoxicity and inhibits the development of diabetic cardiomyopathy in db/db mice.
    Xiong Z; Li Y; Zhao Z; Zhang Y; Man W; Lin J; Dong Y; Liu L; Wang B; Wang H; Guo B; Li C; Li F; Wang H; Sun D
    Biochim Biophys Acta Mol Basis Dis; 2020 Aug; 1866(8):165806. PubMed ID: 32320827
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Stearoyl CoA desaturase is a gatekeeper that protects human beta cells against lipotoxicity and maintains their identity.
    Oshima M; Pechberty S; Bellini L; Göpel SO; Campana M; Rouch C; Dairou J; Cosentino C; Fantuzzi F; Toivonen S; Marchetti P; Magnan C; Cnop M; Le Stunff H; Scharfmann R
    Diabetologia; 2020 Feb; 63(2):395-409. PubMed ID: 31796987
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Nephrin, a transmembrane protein, is involved in pancreatic beta-cell survival signaling.
    Kapodistria K; Tsilibary EP; Politis P; Moustardas P; Charonis A; Kitsiou P
    Mol Cell Endocrinol; 2015 Jan; 400():112-28. PubMed ID: 25448064
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Inhibition of Calcium Influx Reduces Dysfunction and Apoptosis in Lipotoxic Pancreatic β-Cells via Regulation of Endoplasmic Reticulum Stress.
    Zhou Y; Sun P; Wang T; Chen K; Zhu W; Wang H
    PLoS One; 2015; 10(7):e0132411. PubMed ID: 26147439
    [TBL] [Abstract][Full Text] [Related]  

  • 17. MicroRNA-125b-5p improves pancreatic β-cell function through inhibiting JNK signaling pathway by targeting DACT1 in mice with type 2 diabetes mellitus.
    Yu CY; Yang CY; Rui ZL
    Life Sci; 2019 May; 224():67-75. PubMed ID: 30684546
    [TBL] [Abstract][Full Text] [Related]  

  • 18. cGAS-STING mediates cytoplasmic mitochondrial-DNA-induced inflammatory signal transduction during accelerated senescence of pancreatic β-cells induced by metabolic stress.
    Hu H; Zhao R; He Q; Cui C; Song J; Guo X; Zang N; Yang M; Zou Y; Yang J; Li J; Wang L; Xia L; Wang L; He F; Hou X; Yan F; Chen L
    FASEB J; 2022 May; 36(5):e22266. PubMed ID: 35357035
    [TBL] [Abstract][Full Text] [Related]  

  • 19. PLAGL1 overexpression induces cytoplasmic DNA accumulation that triggers cGAS/STING activation.
    Li C; Qiao L; Ge J; Hu S; Yang H; Hu C; Li T
    J Cell Mol Med; 2024 Oct; 28(19):e70130. PubMed ID: 39365284
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Oleic acid protects insulin-secreting INS-1E cells against palmitic acid-induced lipotoxicity along with an amelioration of ER stress.
    Liu X; Zeng X; Chen X; Luo R; Li L; Wang C; Liu J; Cheng J; Lu Y; Chen Y
    Endocrine; 2019 Jun; 64(3):512-524. PubMed ID: 30778898
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.