These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

168 related articles for article (PubMed ID: 32787140)

  • 1. Development of Potent
    Mahindra A; Janha O; Mapesa K; Sanchez-Azqueta A; Alam MM; Amambua-Ngwa A; Nwakanma DC; Tobin AB; Jamieson AG
    J Med Chem; 2020 Sep; 63(17):9300-9315. PubMed ID: 32787140
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Validation of the protein kinase
    Alam MM; Sanchez-Azqueta A; Janha O; Flannery EL; Mahindra A; Mapesa K; Char AB; Sriranganadane D; Brancucci NMB; Antonova-Koch Y; Crouch K; Simwela NV; Millar SB; Akinwale J; Mitcheson D; Solyakov L; Dudek K; Jones C; Zapatero C; Doerig C; Nwakanma DC; Vázquez MJ; Colmenarejo G; Lafuente-Monasterio MJ; Leon ML; Godoi PHC; Elkins JM; Waters AP; Jamieson AG; Álvaro EF; Ranford-Cartwright LC; Marti M; Winzeler EA; Gamo FJ; Tobin AB
    Science; 2019 Aug; 365(6456):. PubMed ID: 31467193
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Temperature does matter-an additional dimension in kinase inhibitor development.
    Strauch M; Heyd F
    FEBS J; 2021 May; 288(10):3148-3153. PubMed ID: 32946682
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis of desaza analogues of annomontine and canthin-4-one alkaloids.
    Strödke B; Gehring AP; Bracher F
    Arch Pharm (Weinheim); 2015 Feb; 348(2):125-31. PubMed ID: 25664630
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Inhibition of the SR protein-phosphorylating CLK kinases of Plasmodium falciparum impairs blood stage replication and malaria transmission.
    Kern S; Agarwal S; Huber K; Gehring AP; Strödke B; Wirth CC; Brügl T; Abodo LO; Dandekar T; Doerig C; Fischer R; Tobin AB; Alam MM; Bracher F; Pradel G
    PLoS One; 2014; 9(9):e105732. PubMed ID: 25188378
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Potent inhibitors of malarial P. Falciparum protein kinase G: Improving the cell activity of a series of imidazopyridines.
    Large JM; Birchall K; Bouloc NS; Merritt AT; Smiljanic-Hurley E; Tsagris DJ; Wheldon MC; Ansell KH; Coombs PJ; Kettleborough CA; Whalley D; Stewart LB; Bowyer PW; Baker DA; Osborne SA
    Bioorg Med Chem Lett; 2019 Feb; 29(3):509-514. PubMed ID: 30553738
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Skeletal hybridization and PfRIO-2 kinase modeling for synthesis of α-pyrone analogs as anti-malarial agent.
    Parveen A; Chakraborty A; Konreddy AK; Chakravarty H; Sharon A; Trivedi V; Bal C
    Eur J Med Chem; 2013; 70():607-12. PubMed ID: 24211636
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Potent Plasmodium falciparum gametocytocidal compounds identified by exploring the kinase inhibitor chemical space for dual active antimalarials.
    van der Watt ME; Reader J; Churchyard A; Nondaba SH; Lauterbach SB; Niemand J; Abayomi S; van Biljon RA; Connacher JI; van Wyk RDJ; Le Manach C; Paquet T; González Cabrera D; Brunschwig C; Theron A; Lozano-Arias S; Rodrigues JFI; Herreros E; Leroy D; Duffy J; Street LJ; Chibale K; Mancama D; Coetzer TL; Birkholtz LM
    J Antimicrob Chemother; 2018 May; 73(5):1279-1290. PubMed ID: 29420756
    [TBL] [Abstract][Full Text] [Related]  

  • 9. 5-Aminopyrazole-4-carboxamide analogues are selective inhibitors of Plasmodium falciparum microgametocyte exflagellation and potential malaria transmission blocking agents.
    Huang W; Hulverson MA; Zhang Z; Choi R; Hart KJ; Kennedy M; Vidadala RSR; Maly DJ; Van Voorhis WC; Lindner SE; Fan E; Ojo KK
    Bioorg Med Chem Lett; 2016 Nov; 26(22):5487-5491. PubMed ID: 27780638
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Plasmodium kinases as targets for new-generation antimalarials.
    Lucet IS; Tobin A; Drewry D; Wilks AF; Doerig C
    Future Med Chem; 2012 Dec; 4(18):2295-310. PubMed ID: 23234552
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Evaluation of the anti-malarial activity and cytotoxicity of 2,4-diamino-pyrimidine-based kinase inhibitors.
    Phuangsawai O; Beswick P; Ratanabunyong S; Tabtimmai L; Suphakun P; Obounchoey P; Srisook P; Horata N; Chuckowree I; Hannongbua S; Ward SE; Choowongkomon K; Gleeson MP
    Eur J Med Chem; 2016 Nov; 124():896-905. PubMed ID: 27668758
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Substituted imidazopyridazines are potent and selective inhibitors of Plasmodium falciparum calcium-dependent protein kinase 1 (PfCDPK1).
    Chapman TM; Osborne SA; Bouloc N; Large JM; Wallace C; Birchall K; Ansell KH; Jones HM; Taylor D; Clough B; Green JL; Holder AA
    Bioorg Med Chem Lett; 2013 May; 23(10):3064-9. PubMed ID: 23570789
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Dibenzylideneacetone analogues as novel Plasmodium falciparum inhibitors.
    Aher RB; Wanare G; Kawathekar N; Kumar RR; Kaushik NK; Sahal D; Chauhan VS
    Bioorg Med Chem Lett; 2011 May; 21(10):3034-6. PubMed ID: 21493068
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Design, economical synthesis and antiplasmodial evaluation of vanillin derived allylated chalcones and their marked synergism with artemisinin against chloroquine resistant strains of Plasmodium falciparum.
    Sharma N; Mohanakrishnan D; Sharma UK; Kumar R; Richa ; Sinha AK; Sahal D
    Eur J Med Chem; 2014 May; 79():350-68. PubMed ID: 24747290
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Novel 2-Phenoxyanilide Congeners Derived from a Hit Structure of the TCAMS: Synthesis and Evaluation of Their in Vitro Activity against Plasmodium falciparum.
    Weidner T; Nasereddin A; Preu L; Grünefeld J; Dzikowski R; Kunick C
    Molecules; 2016 Feb; 21(2):. PubMed ID: 26901174
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Identification, Characterization, and Optimization of 2,8-Disubstituted-1,5-naphthyridines as Novel Plasmodium falciparum Phosphatidylinositol-4-kinase Inhibitors with in Vivo Efficacy in a Humanized Mouse Model of Malaria.
    Kandepedu N; Gonzàlez Cabrera D; Eedubilli S; Taylor D; Brunschwig C; Gibhard L; Njoroge M; Lawrence N; Paquet T; Eyermann CJ; Spangenberg T; Basarab GS; Street LJ; Chibale K
    J Med Chem; 2018 Jul; 61(13):5692-5703. PubMed ID: 29889526
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Trisubstituted thiazoles as potent and selective inhibitors of Plasmodium falciparum protein kinase G (PfPKG).
    Tsagris DJ; Birchall K; Bouloc N; Large JM; Merritt A; Smiljanic-Hurley E; Wheldon M; Ansell KH; Kettleborough C; Whalley D; Stewart LB; Bowyer PW; Baker DA; Osborne SA
    Bioorg Med Chem Lett; 2018 Oct; 28(19):3168-3173. PubMed ID: 30174152
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis of gallinamide A analogues as potent falcipain inhibitors and antimalarials.
    Conroy T; Guo JT; Elias N; Cergol KM; Gut J; Legac J; Khatoon L; Liu Y; McGowan S; Rosenthal PJ; Hunt NH; Payne RJ
    J Med Chem; 2014 Dec; 57(24):10557-63. PubMed ID: 25412465
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Exploration of 3-methylisoquinoline-4-carbonitriles as protein kinase A inhibitors of Plasmodium falciparum.
    Buskes MJ; Harvey KL; Prinz B; Crabb BS; Gilson PR; Wilson DJD; Abbott BM
    Bioorg Med Chem; 2016 Jun; 24(11):2389-2396. PubMed ID: 27112453
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Identification, design and biological evaluation of heterocyclic quinolones targeting Plasmodium falciparum type II NADH:quinone oxidoreductase (PfNDH2).
    Leung SC; Gibbons P; Amewu R; Nixon GL; Pidathala C; Hong WD; Pacorel B; Berry NG; Sharma R; Stocks PA; Srivastava A; Shone AE; Charoensutthivarakul S; Taylor L; Berger O; Mbekeani A; Hill A; Fisher NE; Warman AJ; Biagini GA; Ward SA; O'Neill PM
    J Med Chem; 2012 Mar; 55(5):1844-57. PubMed ID: 22364417
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.