BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

123 related articles for article (PubMed ID: 32787531)

  • 1. Analysis of plant-derived phytochemicals as anti-cancer agents targeting cyclin dependent kinase-2, human topoisomerase IIa and vascular endothelial growth factor receptor-2.
    Sarkar B; Ullah MA; Islam SS; Rahman MH; Araf Y
    J Recept Signal Transduct Res; 2021 Jun; 41(3):217-233. PubMed ID: 32787531
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis, Biological Evaluation and Molecular Docking Study of Cyclic Diarylheptanoids as Potential Anticancer Therapeutics.
    Lu Y; Yin W; Alam MS; Kadi AA; Jahng Y; Kwon Y; Rahman AFMM
    Anticancer Agents Med Chem; 2020; 20(4):464-475. PubMed ID: 31763968
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis, computational quantum chemical study, in silico ADMET and molecular docking analysis, in vitro biological evaluation of a novel sulfur heterocyclic thiophene derivative containing 1,2,3-triazole and pyridine moieties as a potential human topoisomerase IIα inhibiting anticancer agent.
    Murugavel S; Ravikumar C; Jaabil G; Alagusundaram P
    Comput Biol Chem; 2019 Apr; 79():73-82. PubMed ID: 30731361
    [TBL] [Abstract][Full Text] [Related]  

  • 4.
    Das SK; Deka SJ; Paul D; Gupta DD; Das TJ; Maravi DK; Tag H; Hui PK
    J Biomol Struct Dyn; 2022 Sep; 40(15):6857-6867. PubMed ID: 33625319
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Design, Synthesis, In Vitro Anti-cancer Activity, ADMET Profile and Molecular Docking of Novel Triazolo[3,4-a]phthalazine Derivatives Targeting VEGFR-2 Enzyme.
    El-Helby AA; Sakr H; Ayyad RRA; El-Adl K; Ali MM; Khedr F
    Anticancer Agents Med Chem; 2018; 18(8):1184-1196. PubMed ID: 29651967
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Discovery of 3,6-disubstituted pyridazines as a novel class of anticancer agents targeting cyclin-dependent kinase 2: synthesis, biological evaluation and in silico insights.
    Sabt A; Eldehna WM; Al-Warhi T; Alotaibi OJ; Elaasser MM; Suliman H; Abdel-Aziz HA
    J Enzyme Inhib Med Chem; 2020 Dec; 35(1):1616-1630. PubMed ID: 32781872
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Topoisomerases as anticancer targets.
    Delgado JL; Hsieh CM; Chan NL; Hiasa H
    Biochem J; 2018 Jan; 475(2):373-398. PubMed ID: 29363591
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Eco-friendly sequential one-pot synthesis, molecular docking, and anticancer evaluation of arylidene-hydrazinyl-thiazole derivatives as CDK2 inhibitors.
    El-Naggar AM; El-Hashash MA; Elkaeed EB
    Bioorg Chem; 2021 Mar; 108():104615. PubMed ID: 33484942
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Molecular Interaction and Computational Analytical Studies of Pinocembrin for its Antiangiogenic Potential Targeting VEGFR-2: A Persuader of Metastasis.
    Sharma N; Sharma M; Shakeel E; Jamal QMS; Kamal MA; Sayeed U; Khan MKA; Siddiqui MH; Arif JM; Akhtar S
    Med Chem; 2018; 14(6):626-640. PubMed ID: 29663896
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Discovery of new potential CDK2/VEGFR2 type II inhibitors by fragmentation and virtual screening of natural products.
    Vásquez AF; Reyes Muñoz A; Duitama J; González Barrios A
    J Biomol Struct Dyn; 2021 Jun; 39(9):3285-3299. PubMed ID: 32362218
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Molecular Docking of Phytochemicals Targeting GFRs as Therapeutic Sites for Cancer: an In Silico Study.
    Mendie LE; Hemalatha S
    Appl Biochem Biotechnol; 2022 Jan; 194(1):215-231. PubMed ID: 34988844
    [TBL] [Abstract][Full Text] [Related]  

  • 12. EGFR/VEGFR-2 dual inhibitor and apoptotic inducer: Design, synthesis, anticancer activity and docking study of new 2-thioxoimidazolidin-4one derivatives.
    Mourad AAE; Farouk NA; El-Sayed EH; Mahdy ARE
    Life Sci; 2021 Jul; 277():119531. PubMed ID: 33887348
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Design, Synthesis and Docking Studies of Novel Macrocyclic Pentapeptides as Anticancer Multi-Targeted Kinase Inhibitors.
    Amr AEE; Abo-Ghalia MH; Moustafa GO; Al-Omar MA; Nossier ES; Elsayed EA
    Molecules; 2018 Sep; 23(10):. PubMed ID: 30241374
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Design, synthesis, cytotoxicity, HuTopoIIα inhibitory activity and molecular docking studies of pyrazole derivatives as potential anticancer agents.
    Alam R; Wahi D; Singh R; Sinha D; Tandon V; Grover A; Rahisuddin
    Bioorg Chem; 2016 Dec; 69():77-90. PubMed ID: 27744115
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Discovery of novel indolyl-1,2,4-triazole hybrids as potent vascular endothelial growth factor receptor-2 (VEGFR-2) inhibitors with potential anti-renal cancer activity.
    Al-Hussain SA; Farghaly TA; Zaki MEA; Abdulwahab HG; Al-Qurashi NT; Muhammad ZA
    Bioorg Chem; 2020 Dec; 105():104330. PubMed ID: 33038552
    [TBL] [Abstract][Full Text] [Related]  

  • 16. New series of isoxazole derivatives targeting EGFR-TK: Synthesis, molecular modeling and antitumor evaluation.
    Warda ET; Shehata IA; El-Ashmawy MB; El-Gohary NS
    Bioorg Med Chem; 2020 Nov; 28(21):115674. PubMed ID: 33065442
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Selective VEGFR-2 inhibitors: Synthesis of pyridine derivatives, cytotoxicity and apoptosis induction profiling.
    AbdelHaleem A; Mansour AO; AbdelKader M; Arafa RK
    Bioorg Chem; 2020 Oct; 103():104222. PubMed ID: 32889383
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Exploration for novel inhibitors showing back-to-front approach against VEGFR-2 kinase domain (4AG8) employing molecular docking mechanism and molecular dynamics simulations.
    Rampogu S; Baek A; Zeb A; Lee KW
    BMC Cancer; 2018 Mar; 18(1):264. PubMed ID: 29514608
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Bioassays and In Silico Methods in the Identification of Human DNA Topoisomerase IIα Inhibitors.
    Bergant K; Janezic M; Perdih A
    Curr Med Chem; 2018; 25(28):3286-3318. PubMed ID: 29508675
    [TBL] [Abstract][Full Text] [Related]  

  • 20. EGCG regulates the cross-talk between JWA and topoisomerase IIα in non-small-cell lung cancer (NSCLC) cells.
    Li Y; Shen X; Wang X; Li A; Wang P; Jiang P; Zhou J; Feng Q
    Sci Rep; 2015 Jun; 5():11009. PubMed ID: 26046674
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.