160 related articles for article (PubMed ID: 32791146)
1. Tubulin- and ROS-dependent antiproliferative mechanism of a potent analogue of noscapine, N-propargyl noscapine.
Nambiar N; Nagireddy PKR; Pedapati R; Kantevari S; Lopus M
Life Sci; 2020 Oct; 258():118238. PubMed ID: 32791146
[TBL] [Abstract][Full Text] [Related]
2. 9-PAN promotes tubulin- and ROS-mediated cell death in human triple-negative breast cancer cells.
Verma P; Nagireddy PKR; Prassanawar SS; Nirmala JG; Gupta A; Kantevari S; Lopus M
J Pharm Pharmacol; 2020 Nov; 72(11):1585-1594. PubMed ID: 32959391
[TBL] [Abstract][Full Text] [Related]
3. Induction of microtubule hyper stabilization and robust G
Verma P; Manchukonda NK; Kantevari S; Lopus M
Fundam Clin Pharmacol; 2021 Dec; 35(6):955-967. PubMed ID: 33576046
[TBL] [Abstract][Full Text] [Related]
4. Insights into the structure and tubulin-targeted anticancer potential of N-(3-bromobenzyl) noscapine.
Cheriyamundath S; Mahaddalkar T; Reddy Nagireddy PK; Sridhar B; Kantevari S; Lopus M
Pharmacol Rep; 2019 Feb; 71(1):48-53. PubMed ID: 30465924
[TBL] [Abstract][Full Text] [Related]
5. Rational design of novel microtubule targeting anticancer drugs N-imidazopyridine noscapinoids: Chemical synthesis and experimental evaluation based on in vitro using breast cancer cells and in vivo using xenograft mice model.
Pragyandipta P; Pedapati RK; Reddy PK; Nayek A; Meher RK; Guru SK; Kantevari S; Naik PK
Chem Biol Interact; 2023 Sep; 382():110606. PubMed ID: 37330181
[TBL] [Abstract][Full Text] [Related]
6. Induction of acetylation and bundling of cellular microtubules by 9-(4-vinylphenyl) noscapine elicits S-phase arrest in MDA-MB-231 cells.
Cheriyamundath S; Mahaddalkar T; Kantevari S; Lopus M
Biomed Pharmacother; 2017 Feb; 86():74-80. PubMed ID: 27939522
[TBL] [Abstract][Full Text] [Related]
7. Rational design of novel N-alkyl amine analogues of noscapine, their chemical synthesis and cellular activity as potent anticancer agents.
Meher RK; Pragyandipta P; Pedapati RK; Nagireddy PKR; Kantevari S; Nayek AK; Naik PK
Chem Biol Drug Des; 2021 Sep; 98(3):445-465. PubMed ID: 34051055
[TBL] [Abstract][Full Text] [Related]
8. A new antiproliferative noscapine analogue: chemical synthesis and biological evaluation.
Ghaly PE; Abou El-Magd RM; Churchill CD; Tuszynski JA; West FG
Oncotarget; 2016 Jun; 7(26):40518-40530. PubMed ID: 27777381
[TBL] [Abstract][Full Text] [Related]
9. Rational design of biaryl pharmacophore inserted noscapine derivatives as potent tubulin binding anticancer agents.
Santoshi S; Manchukonda NK; Suri C; Sharma M; Sridhar B; Joseph S; Lopus M; Kantevari S; Baitharu I; Naik PK
J Comput Aided Mol Des; 2015 Mar; 29(3):249-70. PubMed ID: 25481458
[TBL] [Abstract][Full Text] [Related]
10. Elucidation of the Tubulin-targeted Mechanism of Action of 9-(3-pyridyl) Noscapine.
Pradhan S; Mahaddalkar T; Choudhary S; Manhcukonda N; Nagireddy PR; Kantevari S; Lopus M
Curr Top Med Chem; 2017; 17(22):2569-2574. PubMed ID: 28056737
[TBL] [Abstract][Full Text] [Related]
11. 9-Arylimino noscapinoids as potent tubulin binding anticancer agent: chemical synthesis and cellular evaluation against breast tumour cells.
Patel AK; Meher RK; Nagireddy PK; Pragyandipta P; Pedapati RK; Kantevari S; Naik PK
SAR QSAR Environ Res; 2021 Apr; 32(4):269-291. PubMed ID: 33687299
[TBL] [Abstract][Full Text] [Related]
12. Novel third-generation water-soluble noscapine analogs as superior microtubule-interfering agents with enhanced antiproliferative activity.
Henary M; Narayana L; Ahad S; Gundala SR; Mukkavilli R; Sharma V; Owens EA; Yadav Y; Nagaraju M; Hamelberg D; Tandon V; Panda D; Aneja R
Biochem Pharmacol; 2014 Nov; 92(2):192-205. PubMed ID: 25124704
[TBL] [Abstract][Full Text] [Related]
13. Synthesis of microtubule-interfering halogenated noscapine analogs that perturb mitosis in cancer cells followed by cell death.
Aneja R; Vangapandu SN; Lopus M; Viswesarappa VG; Dhiman N; Verma A; Chandra R; Panda D; Joshi HC
Biochem Pharmacol; 2006 Aug; 72(4):415-26. PubMed ID: 16780803
[TBL] [Abstract][Full Text] [Related]
14. Rational design, synthesis, and biological evaluation of third generation α-noscapine analogues as potent tubulin binding anti-cancer agents.
Manchukonda NK; Naik PK; Santoshi S; Lopus M; Joseph S; Sridhar B; Kantevari S
PLoS One; 2013; 8(10):e77970. PubMed ID: 24205049
[TBL] [Abstract][Full Text] [Related]
15. Structural Basis of Noscapine Activation for Tubulin Binding.
Oliva MA; Prota AE; Rodríguez-Salarichs J; Bennani YL; Jiménez-Barbero J; Bargsten K; Canales Á; Steinmetz MO; Díaz JF
J Med Chem; 2020 Aug; 63(15):8495-8501. PubMed ID: 32657585
[TBL] [Abstract][Full Text] [Related]
16. A Novel Class of N-Sulfonyl and N-Sulfamoyl Noscapine Derivatives that Promote Mitotic Arrest in Cancer Cells.
Yong C; Devine SM; Gao X; Yan A; Callaghan R; Capuano B; Scammells PJ
ChemMedChem; 2019 Dec; 14(23):1968-1981. PubMed ID: 31714012
[TBL] [Abstract][Full Text] [Related]
17. Structural investigations into the binding mode of a novel noscapine analogue, 9-(4-vinylphenyl) noscapine, with tubulin by biochemical analyses and molecular dynamic simulations.
Mahaddalkar T; Naik PK; Choudhary S; Manchukonda N; Kantevari S; Lopus M
J Biomol Struct Dyn; 2017 Aug; 35(11):2475-2484. PubMed ID: 27576773
[No Abstract] [Full Text] [Related]
18. A Comprehension into Target Binding and Spatial Fingerprints of Noscapinoid Analogues as Inhibitors of Tubulin.
Mandavi S; Verma SK; Banjare L; Dubey A; Bhatt R; Thareja S; Jain AK
Med Chem; 2021; 17(6):611-622. PubMed ID: 31951171
[TBL] [Abstract][Full Text] [Related]
19. Rational design, chemical synthesis and cellular evaluation of novel 1,3-diynyl derivatives of noscapine as potent tubulin binding anticancer agents.
Patel AK; Meher RK; Reddy PK; Pedapati RK; Pragyandipta P; Kantevari S; Naik MR; Naik PK
J Mol Graph Model; 2021 Jul; 106():107933. PubMed ID: 33991960
[TBL] [Abstract][Full Text] [Related]
20. In silico inspired design and synthesis of a novel tubulin-binding anti-cancer drug: folate conjugated noscapine (Targetin).
Naik PK; Lopus M; Aneja R; Vangapandu SN; Joshi HC
J Comput Aided Mol Des; 2012 Feb; 26(2):233-47. PubMed ID: 22170255
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]