These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

275 related articles for article (PubMed ID: 32804090)

  • 1. Presenilin 1 Regulates Membrane Homeostatic Pathways that are Dysregulated in Alzheimer's Disease.
    Deaton CA; Johnson GVW
    J Alzheimers Dis; 2020; 77(3):961-977. PubMed ID: 32804090
    [TBL] [Abstract][Full Text] [Related]  

  • 2. G206D Mutation of Presenilin-1 Reduces Pen2 Interaction, Increases Aβ42/Aβ40 Ratio and Elevates ER Ca(2+) Accumulation.
    Chen WT; Hsieh YF; Huang YJ; Lin CC; Lin YT; Liu YC; Lien CC; Cheng IH
    Mol Neurobiol; 2015 Dec; 52(3):1835-1849. PubMed ID: 25394380
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Alzheimer's disease-causing presenilin-1 mutations have deleterious effects on mitochondrial function.
    Han J; Park H; Maharana C; Gwon AR; Park J; Baek SH; Bae HG; Cho Y; Kim HK; Sul JH; Lee J; Kim E; Kim J; Cho Y; Park S; Palomera LF; Arumugam TV; Mattson MP; Jo DG
    Theranostics; 2021; 11(18):8855-8873. PubMed ID: 34522215
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Attenuated presenilin-1 endoproteolysis enhances store-operated calcium currents in neuronal cells.
    Ryazantseva M; Skobeleva K; Glushankova L; Kaznacheyeva E
    J Neurochem; 2016 Mar; 136(5):1085-95. PubMed ID: 26678016
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Thapsigargin affects presenilin-2 but not presenilin-1 regulation in SK-N-BE cells.
    Rivabene R; Visentin S; Piscopo P; De Nuccio C; Crestini A; Svetoni F; Rosa P; Confaloni A
    Exp Biol Med (Maywood); 2014 Feb; 239(2):213-24. PubMed ID: 24363250
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Familial Alzheimer's disease-associated presenilin-1 alters cerebellar activity and calcium homeostasis.
    Sepulveda-Falla D; Barrera-Ocampo A; Hagel C; Korwitz A; Vinueza-Veloz MF; Zhou K; Schonewille M; Zhou H; Velazquez-Perez L; Rodriguez-Labrada R; Villegas A; Ferrer I; Lopera F; Langer T; De Zeeuw CI; Glatzel M
    J Clin Invest; 2014 Apr; 124(4):1552-67. PubMed ID: 24569455
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Involvement of presenilin holoprotein upregulation in calcium dyshomeostasis of Alzheimer's disease.
    Honarnejad K; Jung CK; Lammich S; Arzberger T; Kretzschmar H; Herms J
    J Cell Mol Med; 2013 Feb; 17(2):293-302. PubMed ID: 23379308
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Susceptibility to cellular stress in PS1 mutant N2a cells is associated with mitochondrial defects and altered calcium homeostasis.
    Rojas-Charry L; Calero-Martinez S; Morganti C; Morciano G; Park K; Hagel C; Marciniak SJ; Glatzel M; Pinton P; Sepulveda-Falla D
    Sci Rep; 2020 Apr; 10(1):6455. PubMed ID: 32296078
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Genes and mechanisms involved in beta-amyloid generation and Alzheimer's disease.
    Steiner H; Capell A; Leimer U; Haass C
    Eur Arch Psychiatry Clin Neurosci; 1999; 249(6):266-70. PubMed ID: 10653281
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Presenilin 1 regulates the processing of beta-amyloid precursor protein C-terminal fragments and the generation of amyloid beta-protein in endoplasmic reticulum and Golgi.
    Xia W; Zhang J; Ostaszewski BL; Kimberly WT; Seubert P; Koo EH; Shen J; Selkoe DJ
    Biochemistry; 1998 Nov; 37(47):16465-71. PubMed ID: 9843412
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Familial Alzheimer's disease-associated presenilin 1 mutants promote γ-secretase cleavage of STIM1 to impair store-operated Ca2+ entry.
    Tong BC; Lee CS; Cheng WH; Lai KO; Foskett JK; Cheung KH
    Sci Signal; 2016 Sep; 9(444):ra89. PubMed ID: 27601731
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Elevated cellular cholesterol in Familial Alzheimer's presenilin 1 mutation is associated with lipid raft localization of β-amyloid precursor protein.
    Cho YY; Kwon OH; Park MK; Kim TW; Chung S
    PLoS One; 2019; 14(1):e0210535. PubMed ID: 30682043
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Familial Alzheimer disease-linked mutations specifically disrupt Ca2+ leak function of presenilin 1.
    Nelson O; Tu H; Lei T; Bentahir M; de Strooper B; Bezprozvanny I
    J Clin Invest; 2007 May; 117(5):1230-9. PubMed ID: 17431506
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Presenilin-1 mutations associated with familial Alzheimer's disease do not disrupt protein transport from the endoplasmic reticulum to the Golgi apparatus.
    Tan Y; Hong J; Doan T; McConlogue L; Maltese WA
    Biochim Biophys Acta; 1998 Jul; 1407(1):69-78. PubMed ID: 9639678
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Lysosome and calcium dysregulation in Alzheimer's disease: partners in crime.
    McBrayer M; Nixon RA
    Biochem Soc Trans; 2013 Dec; 41(6):1495-502. PubMed ID: 24256243
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Retromer and Rab2-dependent trafficking mediate PS1 degradation by proteasomes in endocytic disturbance.
    Ueda N; Tomita T; Yanagisawa K; Kimura N
    J Neurochem; 2016 May; 137(4):647-58. PubMed ID: 26896628
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Repression of transcription of presenilin-1 inhibits γ-secretase independent ER Ca²⁺ leak that is impaired by FAD mutations.
    Das HK; Tchedre K; Mueller B
    J Neurochem; 2012 Aug; 122(3):487-500. PubMed ID: 22607268
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Calcium Signaling and Mitochondrial Function in Presenilin 2 Knock-Out Mice: Looking for Any Loss-of-Function Phenotype Related to Alzheimer's Disease.
    Rossi A; Galla L; Gomiero C; Zentilin L; Giacca M; Giorgio V; Calì T; Pozzan T; Greotti E; Pizzo P
    Cells; 2021 Jan; 10(2):. PubMed ID: 33494218
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Presenilin-2 and Calcium Handling: Molecules, Organelles, Cells and Brain Networks.
    Pizzo P; Basso E; Filadi R; Greotti E; Leparulo A; Pendin D; Redolfi N; Rossini M; Vajente N; Pozzan T; Fasolato C
    Cells; 2020 Sep; 9(10):. PubMed ID: 32992716
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Early Presymptomatic Changes in the Proteome of Mitochondria-Associated Membrane in the APP/PS1 Mouse Model of Alzheimer's Disease.
    Völgyi K; Badics K; Sialana FJ; Gulyássy P; Udvari EB; Kis V; Drahos L; Lubec G; Kékesi KA; Juhász G
    Mol Neurobiol; 2018 Oct; 55(10):7839-7857. PubMed ID: 29468564
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.