160 related articles for article (PubMed ID: 3280991)
1. Activation of anti-Trypanosoma cruzi drugs to genotoxic metabolites promoted by mammalian microsomal enzymes.
Ferreira RC; Schwarz U; Ferreira LC
Mutat Res; 1988 Apr; 204(4):577-83. PubMed ID: 3280991
[TBL] [Abstract][Full Text] [Related]
2. Mutagenicity of nifurtimox and benznidazole in the Salmonella/microsome assay.
Ferreira RC; Ferreira LC
Braz J Med Biol Res; 1986; 19(1):19-25. PubMed ID: 3542090
[TBL] [Abstract][Full Text] [Related]
3. Mutagenicity of 2 anti-chagasic drugs and their metabolic deactivation.
Nagel R; Nepomnaschy I
Mutat Res; 1983; 117(3-4):237-42. PubMed ID: 6406881
[TBL] [Abstract][Full Text] [Related]
4. Evaluation of genotoxic activity in the blood and urine of guinea pigs treated with nifurtimox and benznidazole.
Ferreira RC; de Melo ME; Moraes Júnior MA; Ferreira LC
Braz J Med Biol Res; 1988; 21(5):1069-77. PubMed ID: 3248236
[TBL] [Abstract][Full Text] [Related]
5. Ultrastructural alterations in ovaries from nifurtimox or benznidazole-treated rats: their relation to ovarian nitroreductive biotransformation of both drugs.
de Castro CR; de Toranzo EG; Bernacchi AS; Carbone M; Castro JA
Exp Mol Pathol; 1989 Jun; 50(3):385-97. PubMed ID: 2721655
[TBL] [Abstract][Full Text] [Related]
6. Liver microsomal benznidazole and nifurtimox nitroreductase activity in male rats of different age.
Aguilar E; de Arranz CK; de Toranzo EG; Castro JA
Arch Int Pharmacodyn Ther; 1987 Sep; 289(1):11-7. PubMed ID: 3435199
[TBL] [Abstract][Full Text] [Related]
7. Species and sex differences in the liver microsomal nitroreductive biotransformation of nifurtimox and benznidazole.
Aguilar EG; Koldobsky C; de Toranzo EG; Castro JA
Arch Int Pharmacodyn Ther; 1987 Jun; 287(2):181-7. PubMed ID: 3632141
[TBL] [Abstract][Full Text] [Related]
8. Role of classical nitroreductase and O-acetyltransferase on the mutagenicity of nifurtimox and eight derivatives in Salmonella typhimurium.
Jurado J; Pueyo C
Environ Mol Mutagen; 1995; 26(1):86-93. PubMed ID: 7641712
[TBL] [Abstract][Full Text] [Related]
9. Mutagenicity studies on fenitrothion in bacteria and mammalian cells.
Hara M; Kogiso S; Yamada F; Kawamoto M; Yoshitake A; Miyamoto J
Mutat Res; 1989 Jan; 222(1):53-61. PubMed ID: 2643032
[TBL] [Abstract][Full Text] [Related]
10. Genetic differences between the standard Ames tester strains TA100 and TA98.
Jurado J; Alejandre-Durán E; Pueyo C
Mutagenesis; 1993 Nov; 8(6):527-32. PubMed ID: 8133782
[TBL] [Abstract][Full Text] [Related]
11. Benznidazole and nifurtimox nitroreductase activity in liver microsomes from male rats preinduced with phenobarbital or 3-methylcholanthrene.
Aguilar EG; de Arranz CK; de Toranzo EG; Castro JA
Res Commun Chem Pathol Pharmacol; 1985 Dec; 50(3):443-6. PubMed ID: 3841223
[TBL] [Abstract][Full Text] [Related]
12. Effect of chronic alcohol drinking on rat liver microsomal nitroreductive metabolism of nifurtimox and benznidazole.
de Mecca MM; Bartel LC; Castro JA
Hum Exp Toxicol; 2013 Dec; 32(12):1305-10. PubMed ID: 23698833
[TBL] [Abstract][Full Text] [Related]
13. Delamanid is not metabolized by Salmonella or human nitroreductases: A possible mechanism for the lack of mutagenicity.
Hanaki E; Hayashi M; Matsumoto M
Regul Toxicol Pharmacol; 2017 Mar; 84():1-8. PubMed ID: 27988333
[TBL] [Abstract][Full Text] [Related]
14. Micronucleus formation in bone marrow of mice treated with nifurtimox or benznidazole.
Gorla NB; Castro JA
Toxicol Lett; 1985 Jun; 25(3):259-63. PubMed ID: 4012803
[TBL] [Abstract][Full Text] [Related]
15. Mutagenicity of nitrophenanthrene derivatives for Salmonella typhimurium: effects of nitroreductase and acetyltransferase.
Sera N; Fukuhara K; Miyata N; Tokiwa H
Mutat Res; 1996 Jan; 349(1):137-44. PubMed ID: 8569786
[TBL] [Abstract][Full Text] [Related]
16. Hydroxylation and nitroreduction are required to activate dimethylnitramine into alkylating and mutagenic agents.
Malaveille C; Croisy A; Brun G; Bartsch H
Carcinogenesis; 1983 Nov; 4(11):1477-81. PubMed ID: 6357524
[TBL] [Abstract][Full Text] [Related]
17. Effect of liver enzymes on the mutagenicity of nitroheterocyclic compounds: activation of 3a,4,5,6,7,7a-hexahydro-3-(1-methyl-5-nitro-1H-imidazol-2-yl)- 1,2-benzisoxazole and deactivation of nitrofurans and nitroimidazoles in the Ames test.
Skeggs HR; Berglund RM; VandenHeuvel WJ; Mrozik H; Wislocki PG; Wolf FJ
Mutat Res; 1984 Apr; 136(1):1-8. PubMed ID: 6371510
[TBL] [Abstract][Full Text] [Related]
18. Benznidazole-resistance in Trypanosoma cruzi: evidence that distinct mechanisms can act in concert.
Campos MC; Leon LL; Taylor MC; Kelly JM
Mol Biochem Parasitol; 2014 Jan; 193(1):17-9. PubMed ID: 24462750
[TBL] [Abstract][Full Text] [Related]
19. The reductive metabolism of nifurtimox and benznidazole in Crithidia fasciculata is similar to that in Trypanosoma cruzi.
Moreno SN
Comp Biochem Physiol C Comp Pharmacol Toxicol; 1988; 91(2):321-5. PubMed ID: 2905949
[TBL] [Abstract][Full Text] [Related]
20. Genotoxicity studies with two antichagasic drugs.
Nagel R
Mutat Res; 1987 May; 191(1):17-20. PubMed ID: 3553925
[No Abstract] [Full Text] [Related]
[Next] [New Search]
