BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

230 related articles for article (PubMed ID: 32814529)

  • 1. Insight into Mechanism of Action of Anticancer Benzazoles.
    Ozturk O; Aki-Yalcin E; Yalcin I; Grifitth R
    Curr Top Med Chem; 2020; 20(23):2056-2069. PubMed ID: 32814529
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Recent advances in the development of dual topoisomerase I and II inhibitors as anticancer drugs.
    Salerno S; Da Settimo F; Taliani S; Simorini F; La Motta C; Fornaciari G; Marini AM
    Curr Med Chem; 2010; 17(35):4270-90. PubMed ID: 20939813
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Design, synthesis, molecular docking and anti-proliferative evaluations of [1,2,4]triazolo[4,3-a]quinoxaline derivatives as DNA intercalators and Topoisomerase II inhibitors.
    El-Adl K; El-Helby AA; Sakr H; Elwan A
    Bioorg Chem; 2020 Dec; 105():104399. PubMed ID: 33113414
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Discovery and antiproliferative evaluation of new quinoxalines as potential DNA intercalators and topoisomerase II inhibitors.
    Eissa IH; Metwaly AM; Belal A; Mehany ABM; Ayyad RR; El-Adl K; Mahdy HA; Taghour MS; El-Gamal KMA; El-Sawah ME; Elmetwally SA; Elhendawy MA; Radwan MM; ElSohly MA
    Arch Pharm (Weinheim); 2019 Nov; 352(11):e1900123. PubMed ID: 31463953
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Design and discovery of new 1,2,4-triazolo[4,3-c]quinazolines as potential DNA intercalators and topoisomerase II inhibitors.
    Alesawy MS; Al-Karmalawy AA; Elkaeed EB; Alswah M; Belal A; Taghour MS; Eissa IH
    Arch Pharm (Weinheim); 2021 Mar; 354(3):e2000237. PubMed ID: 33226150
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Antitumor agents 7. Synthesis, antiproliferative activity and molecular modeling of new l-lysine-conjugated pyridophenoxazinones as potent DNA-binding ligands and topoisomerase IIα inhibitors.
    Pedatella S; Cerchia C; Manfra M; Cioce A; Bolognese A; Lavecchia A
    Eur J Med Chem; 2020 Feb; 187():111960. PubMed ID: 31869654
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Design and synthesis of 3,5-substituted 1,2,4-oxadiazoles as catalytic inhibitors of human DNA topoisomerase IIα.
    Loboda KB; Valjavec K; Štampar M; Wolber G; Žegura B; Filipič M; Dolenc MS; Perdih A
    Bioorg Chem; 2020 Jun; 99():103828. PubMed ID: 32315896
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Novel nalidixic acid derivatives targeting topoisomerase II enzyme; Design, synthesis, anticancer activity and effect on cell cycle profile.
    Khalil OM; Gedawy EM; El-Malah AA; Adly ME
    Bioorg Chem; 2019 Mar; 83():262-276. PubMed ID: 30391699
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Design, efficient synthesis, docking studies, and anticancer evaluation of new quinoxalines as potential intercalative Topo II inhibitors and apoptosis inducers.
    Abbass EM; Khalil AK; Mohamed MM; Eissa IH; El-Naggar AM
    Bioorg Chem; 2020 Nov; 104():104255. PubMed ID: 32927130
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Search for human DNA topoisomerase II poisons in the group of 2,5-disubstituted-1,3,4-thiadiazoles.
    Plech T; Kaproń B; Paneth A; Wujec M; Czarnomysy R; Bielawska A; Bielawski K; Trotsko N; Kuśmierz E; Paneth P
    J Enzyme Inhib Med Chem; 2015 Dec; 30(6):1021-6. PubMed ID: 25792499
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Inhibition of topoisomerase IIα and induction of DNA damage in cholangiocarcinoma cells by altholactone and its halogenated benzoate derivatives.
    Kitdumrongthum S; Reabroi S; Suksen K; Tuchinda P; Munyoo B; Mahalapbutr P; Rungrotmongkol T; Ounjai P; Chairoungdua A
    Biomed Pharmacother; 2020 Jul; 127():110149. PubMed ID: 32344256
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Novel xanthone-polyamine conjugates as catalytic inhibitors of human topoisomerase IIα.
    Minniti E; Byl JAW; Riccardi L; Sissi C; Rosini M; De Vivo M; Minarini A; Osheroff N
    Bioorg Med Chem Lett; 2017 Oct; 27(20):4687-4693. PubMed ID: 28919339
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Recent advances in the development of catalytic inhibitors of human DNA topoisomerase IIα as novel anticancer agents.
    Pogorelčnik B; Perdih A; Solmajer T
    Curr Med Chem; 2013; 20(5):694-709. PubMed ID: 23210851
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis and biological evaluation of C1-O-substituted-3-(3-butylamino-2-hydroxy-propoxy)-xanthen-9-one as topoisomerase IIα catalytic inhibitors.
    Park S; Hong E; Kwak SY; Jun KY; Lee ES; Kwon Y; Na Y
    Eur J Med Chem; 2016 Nov; 123():211-225. PubMed ID: 27484510
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Design, synthesis, molecular modeling and anti-proliferative evaluation of novel quinoxaline derivatives as potential DNA intercalators and topoisomerase II inhibitors.
    Ibrahim MK; Taghour MS; Metwaly AM; Belal A; Mehany ABM; Elhendawy MA; Radwan MM; Yassin AM; El-Deeb NM; Hafez EE; ElSohly MA; Eissa IH
    Eur J Med Chem; 2018 Jul; 155():117-134. PubMed ID: 29885574
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Novel DNA topoisomerase IIα inhibitors from combined ligand- and structure-based virtual screening.
    Drwal MN; Marinello J; Manzo SG; Wakelin LP; Capranico G; Griffith R
    PLoS One; 2014; 9(12):e114904. PubMed ID: 25489853
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Discovery of novel triazolophthalazine derivatives as DNA intercalators and topoisomerase II inhibitors.
    Sakr H; Ayyad RR; El-Helby AA; Khalifa MM; Mahdy HA
    Arch Pharm (Weinheim); 2021 Jun; 354(6):e2000456. PubMed ID: 33554352
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Novel ciprofloxacin hybrids using biology oriented drug synthesis (BIODS) approach: Anticancer activity, effects on cell cycle profile, caspase-3 mediated apoptosis, topoisomerase II inhibition, and antibacterial activity.
    Kassab AE; Gedawy EM
    Eur J Med Chem; 2018 Apr; 150():403-418. PubMed ID: 29547830
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Design, molecular modeling and anticancer evaluation of thieno[2,3-d]pyrimidine derivatives as inhibitors of topoisomerase II.
    El-Metwally SA; Khalil AK; El-Sayed WM
    Bioorg Chem; 2020 Jan; 94():103492. PubMed ID: 31864673
    [TBL] [Abstract][Full Text] [Related]  

  • 20. 4β-amidotriazole linked podophyllotoxin congeners: DNA topoisomerase-IIα inhibition and potential anticancer agents for prostate cancer.
    Reddy VG; Bonam SR; Reddy TS; Akunuri R; Naidu VGM; Nayak VL; Bhargava SK; Kumar HMS; Srihari P; Kamal A
    Eur J Med Chem; 2018 Jan; 144():595-611. PubMed ID: 29289884
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.