BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

255 related articles for article (PubMed ID: 32820045)

  • 1. Heterogeneous adaptation of cysteine reactivity to a covalent oncometabolite.
    Perez M; Bak DW; Bergholtz SE; Crooks DR; Arimilli BS; Yang Y; Weerapana E; Linehan WM; Meier JL
    J Biol Chem; 2020 Sep; 295(39):13410-13418. PubMed ID: 32820045
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A chemoproteomic portrait of the oncometabolite fumarate.
    Kulkarni RA; Bak DW; Wei D; Bergholtz SE; Briney CA; Shrimp JH; Alpsoy A; Thorpe AL; Bavari AE; Crooks DR; Levy M; Florens L; Washburn MP; Frizzell N; Dykhuizen EC; Weerapana E; Linehan WM; Meier JL
    Nat Chem Biol; 2019 Apr; 15(4):391-400. PubMed ID: 30718813
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Proteasome inhibition disrupts the metabolism of fumarate hydratase- deficient tumors by downregulating p62 and c-Myc.
    Sourbier C; Ricketts CJ; Liao PJ; Matsumoto S; Wei D; Lang M; Railkar R; Yang Y; Wei MH; Agarwal P; Krishna M; Mitchell JB; Trepel JB; Neckers L; Linehan WM
    Sci Rep; 2019 Dec; 9(1):18409. PubMed ID: 31804603
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Inhibition of mitochondrial aconitase by succination in fumarate hydratase deficiency.
    Ternette N; Yang M; Laroyia M; Kitagawa M; O'Flaherty L; Wolhulter K; Igarashi K; Saito K; Kato K; Fischer R; Berquand A; Kessler BM; Lappin T; Frizzell N; Soga T; Adam J; Pollard PJ
    Cell Rep; 2013 Mar; 3(3):689-700. PubMed ID: 23499446
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Review: Warburg effect and renal cancer caused by errs in fumarate hydratase encoding gene.
    Qureshi AS; Ali S
    Pak J Pharm Sci; 2019 Mar; 32(2):743-749. PubMed ID: 31081789
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Bioorthogonal oncometabolite ligation.
    Briney CA; Najera S; Meier JL
    Methods Enzymol; 2019; 622():431-448. PubMed ID: 31155064
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Estimation of the carrier frequency of fumarate hydratase alterations and implications for kidney cancer risk in hereditary leiomyomatosis and renal cancer.
    Shuch B; Li S; Risch H; Bindra RS; McGillivray PD; Gerstein M
    Cancer; 2020 Aug; 126(16):3657-3666. PubMed ID: 32413184
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Detailed Morphologic and Immunohistochemical Characterization of Myomectomy and Hysterectomy Specimens From Women With Hereditary Leiomyomatosis and Renal Cell Carcinoma Syndrome (HLRCC).
    Chan E; Rabban JT; Mak J; Zaloudek C; Garg K
    Am J Surg Pathol; 2019 Sep; 43(9):1170-1179. PubMed ID: 31162287
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Hereditary leiomyomatosis and renal cell carcinoma syndrome associated uterine smooth muscle tumors: Bridging morphology and clinical screening.
    Garg K; Rabban J
    Genes Chromosomes Cancer; 2021 Mar; 60(3):210-216. PubMed ID: 33099845
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Novel morphological and genetic features of fumarate hydratase deficient renal cell carcinoma in HLRCC syndrome patients with a tailored therapeutic approach.
    Wyvekens N; Valtcheva N; Mischo A; Helmchen B; Hermanns T; Choschzick M; Hötker AM; Rauch A; Mühleisen B; Akhoundova D; Weber A; Moch H; Rupp NJ
    Genes Chromosomes Cancer; 2020 Nov; 59(11):611-619. PubMed ID: 32537760
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Fumarate hydratase inactivation in renal tumors: HIF1α, NRF2, and "cryptic targets" of transcription factors.
    Ooi A; Furge KA
    Chin J Cancer; 2012 Sep; 31(9):413-20. PubMed ID: 22776233
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Utility of prospective pathologic evaluation to inform clinical genetic testing for hereditary leiomyomatosis and renal cell carcinoma.
    Kopp RP; Stratton KL; Glogowski E; Schrader KA; Rau-Murthy R; Russo P; Coleman JA; Offit K
    Cancer; 2017 Jul; 123(13):2452-2458. PubMed ID: 28171700
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Aberrant succination of proteins in fumarate hydratase-deficient mice and HLRCC patients is a robust biomarker of mutation status.
    Bardella C; El-Bahrawy M; Frizzell N; Adam J; Ternette N; Hatipoglu E; Howarth K; O'Flaherty L; Roberts I; Turner G; Taylor J; Giaslakiotis K; Macaulay VM; Harris AL; Chandra A; Lehtonen HJ; Launonen V; Aaltonen LA; Pugh CW; Mihai R; Trudgian D; Kessler B; Baynes JW; Ratcliffe PJ; Tomlinson IP; Pollard PJ
    J Pathol; 2011 Sep; 225(1):4-11. PubMed ID: 21630274
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthetically Lethal Interactions of Heme Oxygenase-1 and Fumarate Hydratase Genes.
    Podkalicka P; Mucha O; Kruczek S; Biela A; Andrysiak K; Stępniewski J; Mikulski M; Gałęzowski M; Sitarz K; Brzózka K; Józkowicz A; Dulak J; Łoboda A
    Biomolecules; 2020 Jan; 10(1):. PubMed ID: 31963199
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Complexities in estimating the true risk of hereditary leiomyomatosis and renal cell carcinoma and the development of kidney cancer.
    Ball MW; Ricketts CJ
    Cancer; 2020 Aug; 126(16):3617-3619. PubMed ID: 32413160
    [No Abstract]   [Full Text] [Related]  

  • 16. Fumarate hydratase as a therapeutic target in renal cancer.
    Kancherla P; Daneshvar M; Sager RA; Mollapour M; Bratslavsky G
    Expert Opin Ther Targets; 2020 Sep; 24(9):923-936. PubMed ID: 32744123
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Proteogenomic landscape of uterine leiomyomas from hereditary leiomyomatosis and renal cell cancer patients.
    Bateman NW; Tarney CM; Abulez T; Soltis AR; Zhou M; Conrads K; Litzi T; Oliver J; Hood B; Driggers P; Viollet C; Dalgard C; Wilkerson M; Catherino W; Hamilton CA; Darcy KM; Casablanca Y; Al-Hendy A; Segars J; Conrads TP; Larry Maxwell G
    Sci Rep; 2021 Apr; 11(1):9371. PubMed ID: 33931688
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Prevalence of somatic and germline mutations of Fumarate hydratase in uterine leiomyomas from young patients.
    Liu C; Dillon J; Beavis AL; Liu Y; Lombardo K; Fader AN; Hung CF; Wu TC; Vang R; Garcia JE; Xing D
    Histopathology; 2020 Feb; 76(3):354-365. PubMed ID: 31564060
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Fumarate Hydratase-deficient Renal Cell Carcinoma Is Strongly Correlated With Fumarate Hydratase Mutation and Hereditary Leiomyomatosis and Renal Cell Carcinoma Syndrome.
    Trpkov K; Hes O; Agaimy A; Bonert M; Martinek P; Magi-Galluzzi C; Kristiansen G; Lüders C; Nesi G; Compérat E; Sibony M; Berney DM; Mehra R; Brimo F; Hartmann A; Husain A; Frizzell N; Hills K; Maclean F; Srinivasan B; Gill AJ
    Am J Surg Pathol; 2016 Jul; 40(7):865-75. PubMed ID: 26900816
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Novel insights into FH-associated disease are KEAPing the lid on oncogenic HIF signalling.
    Adam J; Ratcliffe PJ; Pollard PJ
    Oncotarget; 2011 Nov; 2(11):820-1. PubMed ID: 22064867
    [No Abstract]   [Full Text] [Related]  

    [Next]    [New Search]
    of 13.