329 related articles for article (PubMed ID: 32825675)
1. Ilimaquinone Induces the Apoptotic Cell Death of Cancer Cells by Reducing Pyruvate Dehydrogenase Kinase 1 Activity.
Kwak CH; Jin L; Han JH; Han CW; Kim E; Cho M; Chung TW; Bae SJ; Jang SB; Ha KT
Int J Mol Sci; 2020 Aug; 21(17):. PubMed ID: 32825675
[TBL] [Abstract][Full Text] [Related]
2. Hemistepsin A suppresses colorectal cancer growth through inhibiting pyruvate dehydrogenase kinase activity.
Jin L; Kim EY; Chung TW; Han CW; Park SY; Han JH; Bae SJ; Lee JR; Kim YW; Jang SB; Ha KT
Sci Rep; 2020 Dec; 10(1):21940. PubMed ID: 33318678
[TBL] [Abstract][Full Text] [Related]
3. miR-128-3p contributes to mitochondrial dysfunction and induces apoptosis in glioma cells via targeting pyruvate dehydrogenase kinase 1.
Qu C; Yan C; Cao W; Li F; Qu Y; Guan K; Si C; Yu Z; Qu Z
IUBMB Life; 2020 Mar; 72(3):465-475. PubMed ID: 31828927
[TBL] [Abstract][Full Text] [Related]
4. Overexpression of Pyruvate Dehydrogenase E1α Subunit Inhibits Warburg Effect and Induces Cell Apoptosis Through Mitochondria-Mediated Pathway in Hepatocellular Carcinoma.
Sun J; Li J; Guo Z; Sun L; Juan C; Zhou Y; Gu H; Yu Y; Hu Q; Kan Q; Yu Z
Oncol Res; 2019 Mar; 27(4):407-414. PubMed ID: 29444744
[TBL] [Abstract][Full Text] [Related]
5. A novel PDK1 inhibitor, JX06, inhibits glycolysis and induces apoptosis in multiple myeloma cells.
Kawano Y; Sasano T; Arima Y; Kushima S; Tsujita K; Matsuoka M; Hata H
Biochem Biophys Res Commun; 2022 Jan; 587():153-159. PubMed ID: 34875534
[TBL] [Abstract][Full Text] [Related]
6. SIRT3 elicited an anti-Warburg effect through HIF1α/PDK1/PDHA1 to inhibit cholangiocarcinoma tumorigenesis.
Xu L; Li Y; Zhou L; Dorfman RG; Liu L; Cai R; Jiang C; Tang D; Wang Y; Zou X; Wang L; Zhang M
Cancer Med; 2019 May; 8(5):2380-2391. PubMed ID: 30993888
[TBL] [Abstract][Full Text] [Related]
7. Inhibition of pyruvate dehydrogenase kinase‑1 by dicoumarol enhances the sensitivity of hepatocellular carcinoma cells to oxaliplatin via metabolic reprogramming.
Xu H; He Y; Ma J; Zhao Y; Liu Y; Sun L; Su J
Int J Oncol; 2020 Sep; 57(3):733-742. PubMed ID: 32705170
[TBL] [Abstract][Full Text] [Related]
8. ROS production induced by BRAF inhibitor treatment rewires metabolic processes affecting cell growth of melanoma cells.
Cesi G; Walbrecq G; Zimmer A; Kreis S; Haan C
Mol Cancer; 2017 Jun; 16(1):102. PubMed ID: 28595656
[TBL] [Abstract][Full Text] [Related]
9. Targeting pyruvate dehydrogenase kinase signaling in the development of effective cancer therapy.
Anwar S; Shamsi A; Mohammad T; Islam A; Hassan MI
Biochim Biophys Acta Rev Cancer; 2021 Aug; 1876(1):188568. PubMed ID: 34023419
[TBL] [Abstract][Full Text] [Related]
10. Overexpression of pyruvate dehydrogenase kinase 1 and lactate dehydrogenase A in nerve cells confers resistance to amyloid β and other toxins by decreasing mitochondrial respiration and reactive oxygen species production.
Newington JT; Rappon T; Albers S; Wong DY; Rylett RJ; Cumming RC
J Biol Chem; 2012 Oct; 287(44):37245-58. PubMed ID: 22948140
[TBL] [Abstract][Full Text] [Related]
11. Phenyl butyrate inhibits pyruvate dehydrogenase kinase 1 and contributes to its anti-cancer effect.
Zhang W; Zhang SL; Hu X; Tam KY
Eur J Pharm Sci; 2017 Dec; 110():93-100. PubMed ID: 28450154
[TBL] [Abstract][Full Text] [Related]
12. Huzhangoside A Suppresses Tumor Growth through Inhibition of Pyruvate Dehydrogenase Kinase Activity.
Kwak CH; Lee JH; Kim EY; Han CW; Kim KJ; Lee H; Cho M; Jang SB; Kim CH; Chung TW; Ha KT
Cancers (Basel); 2019 May; 11(5):. PubMed ID: 31126094
[TBL] [Abstract][Full Text] [Related]
13. Anemone rivularis inhibits pyruvate dehydrogenase kinase activity and tumor growth.
Chung TW; Lee JH; Choi HJ; Park MJ; Kim EY; Han JH; Jang SB; Lee SO; Lee SW; Hang J; Yi LW; Ha KT
J Ethnopharmacol; 2017 May; 203():47-54. PubMed ID: 28341246
[TBL] [Abstract][Full Text] [Related]
14. Andrographolide suppresses aerobic glycolysis and induces apoptotic cell death by inhibiting pyruvate dehydrogenase kinase 1 expression.
Yang ES; Do Y; Cheon SY; Kim B; Ling J; Cho MK; Kim T; Bae SJ; Ha KT
Oncol Rep; 2023 Apr; 49(4):. PubMed ID: 36825595
[TBL] [Abstract][Full Text] [Related]
15. Src drives the Warburg effect and therapy resistance by inactivating pyruvate dehydrogenase through tyrosine-289 phosphorylation.
Jin Y; Cai Q; Shenoy AK; Lim S; Zhang Y; Charles S; Tarrash M; Fu X; Kamarajugadda S; Trevino JG; Tan M; Lu J
Oncotarget; 2016 May; 7(18):25113-24. PubMed ID: 26848621
[TBL] [Abstract][Full Text] [Related]
16. Reducing Oxidative Stress and Inflammation by Pyruvate Dehydrogenase Kinase 4 Inhibition Is Important in Prevention of Renal Ischemia-Reperfusion Injury in Diabetic Mice.
Khang AR; Kim DH; Kim MJ; Oh CJ; Jeon JH; Choi SH; Lee IK
Diabetes Metab J; 2024 May; 48(3):405-417. PubMed ID: 38311057
[TBL] [Abstract][Full Text] [Related]
17. Tyr-301 phosphorylation inhibits pyruvate dehydrogenase by blocking substrate binding and promotes the Warburg effect.
Fan J; Kang HB; Shan C; Elf S; Lin R; Xie J; Gu TL; Aguiar M; Lonning S; Chung TW; Arellano M; Khoury HJ; Shin DM; Khuri FR; Boggon TJ; Kang S; Chen J
J Biol Chem; 2014 Sep; 289(38):26533-26541. PubMed ID: 25104357
[TBL] [Abstract][Full Text] [Related]
18. Ilimaquinone, a marine sponge metabolite, displays anticancer activity via GADD153-mediated pathway.
Lu PH; Chueh SC; Kung FL; Pan SL; Shen YC; Guh JH
Eur J Pharmacol; 2007 Feb; 556(1-3):45-54. PubMed ID: 17140562
[TBL] [Abstract][Full Text] [Related]
19. Combined inhibition of pyruvate dehydrogenase kinase 1 and lactate dehydrogenase a induces metabolic and signaling reprogramming and enhances lung adenocarcinoma cell killing.
Zhou Y; Guo Y; Ran M; Shan W; Granchi C; Giovannetti E; Minutolo F; Peters GJ; Tam KY
Cancer Lett; 2023 Nov; 577():216425. PubMed ID: 37805163
[TBL] [Abstract][Full Text] [Related]
20. SIRT3 deacetylates and increases pyruvate dehydrogenase activity in cancer cells.
Ozden O; Park SH; Wagner BA; Song HY; Zhu Y; Vassilopoulos A; Jung B; Buettner GR; Gius D
Free Radic Biol Med; 2014 Nov; 76():163-172. PubMed ID: 25152236
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
