BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

472 related articles for article (PubMed ID: 32830299)

  • 1. Unravelling the anticancer potency of 1,2,4-triazole-N-arylamide hybrids through inhibition of STAT3: synthesis and in silico mechanistic studies.
    Turky A; Bayoumi AH; Sherbiny FF; El-Adl K; Abulkhair HS
    Mol Divers; 2021 Feb; 25(1):403-420. PubMed ID: 32830299
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Novel 1,2,4-triazole derivatives: Design, synthesis, anticancer evaluation, molecular docking, and pharmacokinetic profiling studies.
    Turky A; Sherbiny FF; Bayoumi AH; Ahmed HEA; Abulkhair HS
    Arch Pharm (Weinheim); 2020 Dec; 353(12):e2000170. PubMed ID: 32893368
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Design, Synthesis, In Vitro Anti-cancer Activity, ADMET Profile and Molecular Docking of Novel Triazolo[3,4-a]phthalazine Derivatives Targeting VEGFR-2 Enzyme.
    El-Helby AA; Sakr H; Ayyad RRA; El-Adl K; Ali MM; Khedr F
    Anticancer Agents Med Chem; 2018; 18(8):1184-1196. PubMed ID: 29651967
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Design, Synthesis and Antiproliferative Evaluation of Novel 1,2,4-Triazole/Schiff Base Hybrids with EGFR and B-RAF Inhibitory Activities.
    El-Sherief HAM; Youssif BGM; Abdelazeem AH; Abdel-Aziz M; Abdel-Rahman HM
    Anticancer Agents Med Chem; 2019; 19(5):697-706. PubMed ID: 30582484
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The In Vitro Anticancer Activity and Potential Mechanism of Action of 1-[(1R,2S)-2-fluorocyclopropyl]Ciprofloxacin-(4-methyl/phenyl/benzyl-3- aryl)-1,2,4-triazole-5(4H)-thione Hybrids.
    Zhang YZ; Liu HL; He QS; Xu Z
    Curr Top Med Chem; 2020; 20(16):1493-1498. PubMed ID: 32156237
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Design, synthesis and molecular docking studies of thymol based 1,2,3-triazole hybrids as thymidylate synthase inhibitors and apoptosis inducers against breast cancer cells.
    Alam MM; Malebari AM; Syed N; Neamatallah T; Almalki ASA; Elhenawy AA; Obaid RJ; Alsharif MA
    Bioorg Med Chem; 2021 May; 38():116136. PubMed ID: 33894490
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Design and Synthesis of Novel Imidazole Derivatives Possessing Triazole Pharmacophore with Potent Anticancer Activity, and In Silico ADMET with GSK-3β Molecular Docking Investigations.
    Al-Blewi F; Shaikh SA; Naqvi A; Aljohani F; Aouad MR; Ihmaid S; Rezki N
    Int J Mol Sci; 2021 Jan; 22(3):. PubMed ID: 33503871
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis, in vitro anticancer and antibacterial activities and in silico studies of new 4-substituted 1,2,3-triazole-coumarin hybrids.
    Kraljević TG; Harej A; Sedić M; Pavelić SK; Stepanić V; Drenjančević D; Talapko J; Raić-Malić S
    Eur J Med Chem; 2016 Nov; 124():794-808. PubMed ID: 27639370
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Design of molecular hybrids of phthalimide-triazole agents with potent selective MCF-7/HepG2 cytotoxicity: Synthesis, EGFR inhibitory effect, and metabolic stability.
    Ihmaid SK; Alraqa SY; Aouad MR; Aljuhani A; Elbadawy HM; Salama SA; Rezki N; Ahmed HEA
    Bioorg Chem; 2021 Jun; 111():104835. PubMed ID: 33798850
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Targeting the interplay between MMP-2, CA II and VEGFR-2 via new sulfonamide-tethered isomeric triazole hybrids; Microwave-assisted synthesis, computational studies and evaluation.
    Reda Aouad M; Almehmadi MA; Faleh Albelwi F; Teleb M; Tageldin GN; Abu-Serie MM; Hagar M; Rezki N
    Bioorg Chem; 2022 Jul; 124():105816. PubMed ID: 35489270
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis and biological evaluation of some novel 1,2,3-triazole hybrids of myrrhanone B isolated from Commiphora mukul gum resin: Identification of potent antiproliferative leads active against prostate cancer cells (PC-3).
    Madasu C; Karri S; Sangaraju R; Sistla R; Uppuluri MV
    Eur J Med Chem; 2020 Feb; 188():111974. PubMed ID: 31883489
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Novel benzotriazole N-acylarylhydrazone hybrids: Design, synthesis, anticancer activity, effects on cell cycle profile, caspase-3 mediated apoptosis and FAK inhibition.
    Kassab AE; Hassan RA
    Bioorg Chem; 2018 Oct; 80():531-544. PubMed ID: 30014921
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Moxifloxacin-isatin Hybrids Tethered by 1,2,3-triazole and their Anticancer Activities.
    Yang M; Liu H; Zhang Y; Wang X; Xu Z
    Curr Top Med Chem; 2020; 20(16):1461-1467. PubMed ID: 31994464
    [TBL] [Abstract][Full Text] [Related]  

  • 14. New 1,2,3-Triazole-Containing Hybrids as Antitumor Candidates: Design, Click Reaction Synthesis, DFT Calculations, and Molecular Docking Study.
    El Azab IH; El-Sheshtawy HS; Bakr RB; Elkanzi NAA
    Molecules; 2021 Jan; 26(3):. PubMed ID: 33573040
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Design, synthesis, molecular docking and anti-proliferative evaluations of [1,2,4]triazolo[4,3-a]quinoxaline derivatives as DNA intercalators and Topoisomerase II inhibitors.
    El-Adl K; El-Helby AA; Sakr H; Elwan A
    Bioorg Chem; 2020 Dec; 105():104399. PubMed ID: 33113414
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Novel benzimidazole-triazole hybrids as apoptosis inducing agents in lung cancer: Design, synthesis,
    Sridhar Goud N; Pooladanda V; Muni Chandra K; Lakshmi Soukya PS; Alvala R; Kumar P; Nagaraj C; Dawn Bharath R; Qureshi IA; Godugu C; Alvala M
    Bioorg Chem; 2020 Sep; 102():104125. PubMed ID: 32738568
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis, anticancer activity and molecular modeling studies of 1,2,4-triazole derivatives as EGFR inhibitors.
    El-Sherief HAM; Youssif BGM; Abbas Bukhari SN; Abdelazeem AH; Abdel-Aziz M; Abdel-Rahman HM
    Eur J Med Chem; 2018 Aug; 156():774-789. PubMed ID: 30055463
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Discovery of novel indolyl-1,2,4-triazole hybrids as potent vascular endothelial growth factor receptor-2 (VEGFR-2) inhibitors with potential anti-renal cancer activity.
    Al-Hussain SA; Farghaly TA; Zaki MEA; Abdulwahab HG; Al-Qurashi NT; Muhammad ZA
    Bioorg Chem; 2020 Dec; 105():104330. PubMed ID: 33038552
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Design, synthesis and molecular docking studies of novel N-benzenesulfonyl-1,2,3,4-tetrahydroisoquinoline-based triazoles with potential anticancer activity.
    Pingaew R; Mandi P; Nantasenamat C; Prachayasittikul S; Ruchirawat S; Prachayasittikul V
    Eur J Med Chem; 2014 Jun; 81():192-203. PubMed ID: 24836071
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A Novel Series of N-aryltriazole and N-acridinyltriazole Hybrids as Potential Anticancer Agents.
    Rono CK; Darkwa J; Meyer D; Makhubela BCE
    Curr Org Synth; 2019; 16(6):900-912. PubMed ID: 31984911
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 24.