289 related articles for article (PubMed ID: 32830871)
21. The C9orf72 GGGGCC repeat is translated into aggregating dipeptide-repeat proteins in FTLD/ALS.
Mori K; Weng SM; Arzberger T; May S; Rentzsch K; Kremmer E; Schmid B; Kretzschmar HA; Cruts M; Van Broeckhoven C; Haass C; Edbauer D
Science; 2013 Mar; 339(6125):1335-8. PubMed ID: 23393093
[TBL] [Abstract][Full Text] [Related]
22. Evidence that C9ORF72 Dipeptide Repeat Proteins Associate with U2 snRNP to Cause Mis-splicing in ALS/FTD Patients.
Yin S; Lopez-Gonzalez R; Kunz RC; Gangopadhyay J; Borufka C; Gygi SP; Gao FB; Reed R
Cell Rep; 2017 Jun; 19(11):2244-2256. PubMed ID: 28614712
[TBL] [Abstract][Full Text] [Related]
23. The porphyrin TMPyP4 inhibits elongation during the noncanonical translation of the FTLD/ALS-associated GGGGCC repeat in the C9orf72 gene.
Mori K; Gotoh S; Yamashita T; Uozumi R; Kawabe Y; Tagami S; Kamp F; Nuscher B; Edbauer D; Haass C; Nagai Y; Ikeda M
J Biol Chem; 2021 Oct; 297(4):101120. PubMed ID: 34450161
[TBL] [Abstract][Full Text] [Related]
24. NUP62 localizes to ALS/FTLD pathological assemblies and contributes to TDP-43 insolubility.
Gleixner AM; Verdone BM; Otte CG; Anderson EN; Ramesh N; Shapiro OR; Gale JR; Mauna JC; Mann JR; Copley KE; Daley EL; Ortega JA; Cicardi ME; Kiskinis E; Kofler J; Pandey UB; Trotti D; Donnelly CJ
Nat Commun; 2022 Jun; 13(1):3380. PubMed ID: 35697676
[TBL] [Abstract][Full Text] [Related]
25. C9orf72 isoforms in Amyotrophic Lateral Sclerosis and Frontotemporal Lobar Degeneration.
Xiao S; MacNair L; McLean J; McGoldrick P; McKeever P; Soleimani S; Keith J; Zinman L; Rogaeva E; Robertson J
Brain Res; 2016 Sep; 1647():43-49. PubMed ID: 27134035
[TBL] [Abstract][Full Text] [Related]
26. RNA Dysmetabolism and Repeat-Associated Non-AUG Translation in Frontotemporal Lobar Degeneration/Amyotrophic Lateral Sclerosis due to
Mori K; Gotoh S; Uozumi R; Miyamoto T; Akamine S; Kawabe Y; Tagami S; Ikeda M
JMA J; 2023 Jan; 6(1):9-15. PubMed ID: 36793534
[TBL] [Abstract][Full Text] [Related]
27. Pathogenic determinants and mechanisms of ALS/FTD linked to hexanucleotide repeat expansions in the C9orf72 gene.
Wen X; Westergard T; Pasinelli P; Trotti D
Neurosci Lett; 2017 Jan; 636():16-26. PubMed ID: 27619540
[TBL] [Abstract][Full Text] [Related]
28. Antisense RNA foci in the motor neurons of C9ORF72-ALS patients are associated with TDP-43 proteinopathy.
Cooper-Knock J; Higginbottom A; Stopford MJ; Highley JR; Ince PG; Wharton SB; Pickering-Brown S; Kirby J; Hautbergue GM; Shaw PJ
Acta Neuropathol; 2015 Jul; 130(1):63-75. PubMed ID: 25943887
[TBL] [Abstract][Full Text] [Related]
29. Aberrant deposition of stress granule-resident proteins linked to C9orf72-associated TDP-43 proteinopathy.
Chew J; Cook C; Gendron TF; Jansen-West K; Del Rosso G; Daughrity LM; Castanedes-Casey M; Kurti A; Stankowski JN; Disney MD; Rothstein JD; Dickson DW; Fryer JD; Zhang YJ; Petrucelli L
Mol Neurodegener; 2019 Feb; 14(1):9. PubMed ID: 30767771
[TBL] [Abstract][Full Text] [Related]
30. Sense and antisense RNA are not toxic in Drosophila models of C9orf72-associated ALS/FTD.
Moens TG; Mizielinska S; Niccoli T; Mitchell JS; Thoeng A; Ridler CE; Grönke S; Esser J; Heslegrave A; Zetterberg H; Partridge L; Isaacs AM
Acta Neuropathol; 2018 Mar; 135(3):445-457. PubMed ID: 29380049
[TBL] [Abstract][Full Text] [Related]
31. Reduced hnRNPA3 increases C9orf72 repeat RNA levels and dipeptide-repeat protein deposition.
Mori K; Nihei Y; Arzberger T; Zhou Q; Mackenzie IR; Hermann A; Hanisch F; ; ; Kamp F; Nuscher B; Orozco D; Edbauer D; Haass C
EMBO Rep; 2016 Sep; 17(9):1314-25. PubMed ID: 27461252
[TBL] [Abstract][Full Text] [Related]
32. Cell-to-Cell Transmission of Dipeptide Repeat Proteins Linked to C9orf72-ALS/FTD.
Westergard T; Jensen BK; Wen X; Cai J; Kropf E; Iacovitti L; Pasinelli P; Trotti D
Cell Rep; 2016 Oct; 17(3):645-652. PubMed ID: 27732842
[TBL] [Abstract][Full Text] [Related]
33. Distribution of dipeptide repeat proteins in cellular models and C9orf72 mutation cases suggests link to transcriptional silencing.
Schludi MH; May S; Grässer FA; Rentzsch K; Kremmer E; Küpper C; Klopstock T; ; ; Arzberger T; Edbauer D
Acta Neuropathol; 2015 Oct; 130(4):537-55. PubMed ID: 26085200
[TBL] [Abstract][Full Text] [Related]
34. Accumulation of dipeptide repeat proteins predates that of TDP-43 in frontotemporal lobar degeneration associated with hexanucleotide repeat expansions in C9ORF72 gene.
Baborie A; Griffiths TD; Jaros E; Perry R; McKeith IG; Burn DJ; Masuda-Suzukake M; Hasegawa M; Rollinson S; Pickering-Brown S; Robinson AC; Davidson YS; Mann DM
Neuropathol Appl Neurobiol; 2015 Aug; 41(5):601-12. PubMed ID: 25185840
[TBL] [Abstract][Full Text] [Related]
35. The DNA damage response (DDR) is induced by the C9orf72 repeat expansion in amyotrophic lateral sclerosis.
Farg MA; Konopka A; Soo KY; Ito D; Atkin JD
Hum Mol Genet; 2017 Aug; 26(15):2882-2896. PubMed ID: 28481984
[TBL] [Abstract][Full Text] [Related]
36. Dipeptide repeat proteins activate a heat shock response found in C9ORF72-ALS/FTLD patients.
Mordes DA; Prudencio M; Goodman LD; Klim JR; Moccia R; Limone F; Pietilainen O; Chowdhary K; Dickson DW; Rademakers R; Bonini NM; Petrucelli L; Eggan K
Acta Neuropathol Commun; 2018 Jul; 6(1):55. PubMed ID: 29973287
[TBL] [Abstract][Full Text] [Related]
37. Unaffected mosaic
McGoldrick P; Zhang M; van Blitterswijk M; Sato C; Moreno D; Xiao S; Zhang AB; McKeever PM; Weichert A; Schneider R; Keith J; Petrucelli L; Rademakers R; Zinman L; Robertson J; Rogaeva E
Neurology; 2018 Jan; 90(4):e323-e331. PubMed ID: 29282338
[TBL] [Abstract][Full Text] [Related]
38. The Genetics of
Gijselinck I; Cruts M; Van Broeckhoven C
Cold Spring Harb Perspect Med; 2018 Apr; 8(4):. PubMed ID: 28130313
[TBL] [Abstract][Full Text] [Related]
39. Increased prevalence of granulovacuolar degeneration in C9orf72 mutation.
Riku Y; Duyckaerts C; Boluda S; Plu I; Le Ber I; Millecamps S; Salachas F; ; Yoshida M; Ando T; Katsuno M; Sobue G; Seilhean D
Acta Neuropathol; 2019 Nov; 138(5):783-793. PubMed ID: 31144027
[TBL] [Abstract][Full Text] [Related]
40. Molecular Mechanisms of Neurodegeneration Related to
Babić Leko M; Župunski V; Kirincich J; Smilović D; Hortobágyi T; Hof PR; Šimić G
Behav Neurol; 2019; 2019():2909168. PubMed ID: 30774737
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]