249 related articles for article (PubMed ID: 32835772)
21. Pathogenic mutation in the ALS/FTD gene, CCNF, causes elevated Lys48-linked ubiquitylation and defective autophagy.
Lee A; Rayner SL; Gwee SSL; De Luca A; Shahheydari H; Sundaramoorthy V; Ragagnin A; Morsch M; Radford R; Galper J; Freckleton S; Shi B; Walker AK; Don EK; Cole NJ; Yang S; Williams KL; Yerbury JJ; Blair IP; Atkin JD; Molloy MP; Chung RS
Cell Mol Life Sci; 2018 Jan; 75(2):335-354. PubMed ID: 28852778
[TBL] [Abstract][Full Text] [Related]
22. The SQSTM1/p62 UBA domain regulates Ajuba localisation, degradation and NF-κB signalling function.
Sultana MA; Cluning C; Kwong WS; Polain N; Pavlos NJ; Ratajczak T; Walsh JP; Xu J; Rea SL
PLoS One; 2021; 16(11):e0259556. PubMed ID: 34735553
[TBL] [Abstract][Full Text] [Related]
23. SQSTM1 mutations in frontotemporal lobar degeneration and amyotrophic lateral sclerosis.
Rubino E; Rainero I; Chiò A; Rogaeva E; Galimberti D; Fenoglio P; Grinberg Y; Isaia G; Calvo A; Gentile S; Bruni AC; St George-Hyslop PH; Scarpini E; Gallone S; Pinessi L;
Neurology; 2012 Oct; 79(15):1556-62. PubMed ID: 22972638
[TBL] [Abstract][Full Text] [Related]
24. UBQLN2 Promotes the Production of Type I Interferon via the TBK1-IRF3 Pathway.
Chen T; Zhang W; Huang B; Chen X; Huang C
Cells; 2020 May; 9(5):. PubMed ID: 32413959
[TBL] [Abstract][Full Text] [Related]
25. NIMA-related kinase 9-mediated phosphorylation of the microtubule-associated LC3B protein at Thr-50 suppresses selective autophagy of p62/sequestosome 1.
Shrestha BK; Skytte Rasmussen M; Abudu YP; Bruun JA; Larsen KB; Alemu EA; Sjøttem E; Lamark T; Johansen T
J Biol Chem; 2020 Jan; 295(5):1240-1260. PubMed ID: 31857374
[TBL] [Abstract][Full Text] [Related]
26. TBK1 mutation frequencies in French frontotemporal dementia and amyotrophic lateral sclerosis cohorts.
Le Ber I; De Septenville A; Millecamps S; Camuzat A; Caroppo P; Couratier P; Blanc F; Lacomblez L; Sellal F; Fleury MC; Meininger V; Cazeneuve C; Clot F; Flabeau O; LeGuern E; Brice A;
Neurobiol Aging; 2015 Nov; 36(11):3116.e5-3116.e8. PubMed ID: 26476236
[TBL] [Abstract][Full Text] [Related]
27. Autophagy and ALS: mechanistic insights and therapeutic implications.
Chua JP; De Calbiac H; Kabashi E; Barmada SJ
Autophagy; 2022 Feb; 18(2):254-282. PubMed ID: 34057020
[TBL] [Abstract][Full Text] [Related]
28. Dynamic recruitment and activation of ALS-associated TBK1 with its target optineurin are required for efficient mitophagy.
Moore AS; Holzbaur EL
Proc Natl Acad Sci U S A; 2016 Jun; 113(24):E3349-58. PubMed ID: 27247382
[TBL] [Abstract][Full Text] [Related]
29. Functional links between SQSTM1 and ALS2 in the pathogenesis of ALS: cumulative impact on the protection against mutant SOD1-mediated motor dysfunction in mice.
Hadano S; Mitsui S; Pan L; Otomo A; Kubo M; Sato K; Ono S; Onodera W; Abe K; Chen X; Koike M; Uchiyama Y; Aoki M; Warabi E; Yamamoto M; Ishii T; Yanagawa T; Shang HF; Yoshii F
Hum Mol Genet; 2016 Aug; 25(15):3321-3340. PubMed ID: 27439389
[TBL] [Abstract][Full Text] [Related]
30. Two FTD-ALS genes converge on the endosomal pathway to induce TDP-43 pathology and degeneration.
Shao W; Todd TW; Wu Y; Jones CY; Tong J; Jansen-West K; Daughrity LM; Park J; Koike Y; Kurti A; Yue M; Castanedes-Casey M; Del Rosso G; Dunmore JA; Zanetti Alepuz D; Oskarsson B; Dickson DW; Cook CN; Prudencio M; Gendron TF; Fryer JD; Zhang YJ; Petrucelli L
Science; 2022 Oct; 378(6615):94-99. PubMed ID: 36201573
[TBL] [Abstract][Full Text] [Related]
31. TBK1 controls autophagosomal engulfment of polyubiquitinated mitochondria through p62/SQSTM1 phosphorylation.
Matsumoto G; Shimogori T; Hattori N; Nukina N
Hum Mol Genet; 2015 Aug; 24(15):4429-42. PubMed ID: 25972374
[TBL] [Abstract][Full Text] [Related]
32. TDP-43 is consistently co-localized with ubiquitinated inclusions in sporadic and Guam amyotrophic lateral sclerosis but not in familial amyotrophic lateral sclerosis with and without SOD1 mutations.
Maekawa S; Leigh PN; King A; Jones E; Steele JC; Bodi I; Shaw CE; Hortobagyi T; Al-Sarraj S
Neuropathology; 2009 Dec; 29(6):672-83. PubMed ID: 19496940
[TBL] [Abstract][Full Text] [Related]
33. TBK1 Mutation Spectrum in an Extended European Patient Cohort with Frontotemporal Dementia and Amyotrophic Lateral Sclerosis.
van der Zee J; Gijselinck I; Van Mossevelde S; Perrone F; Dillen L; Heeman B; Bäumer V; Engelborghs S; De Bleecker J; Baets J; Gelpi E; Rojas-García R; Clarimón J; Lleó A; Diehl-Schmid J; Alexopoulos P; Perneczky R; Synofzik M; Just J; Schöls L; Graff C; Thonberg H; Borroni B; Padovani A; Jordanova A; Sarafov S; Tournev I; de Mendonça A; Miltenberger-Miltényi G; Simões do Couto F; Ramirez A; Jessen F; Heneka MT; Gómez-Tortosa E; Danek A; Cras P; Vandenberghe R; De Jonghe P; De Deyn PP; Sleegers K; Cruts M; Van Broeckhoven C; Goeman J; Nuytten D; Smets K; Robberecht W; Damme PV; Bleecker J; Santens P; Dermaut B; Versijpt J; Michotte A; Ivanoiu A; Deryck O; Bergmans B; Delbeck J; Bruyland M; Willems C; Salmon E; Pastor P; Ortega-Cubero S; Benussi L; Ghidoni R; Binetti G; Hernández I; Boada M; Ruiz A; Sorbi S; Nacmias B; Bagnoli S; Sorbi S; Sanchez-Valle R; Llado A; Santana I; Rosário Almeida M; Frisoni GB; Maetzler W; Matej R; Fraidakis MJ; Kovacs GG; Fabrizi GM; Testi S
Hum Mutat; 2017 Mar; 38(3):297-309. PubMed ID: 28008748
[TBL] [Abstract][Full Text] [Related]
34. p62 positive, TDP-43 negative, neuronal cytoplasmic and intranuclear inclusions in the cerebellum and hippocampus define the pathology of C9orf72-linked FTLD and MND/ALS.
Al-Sarraj S; King A; Troakes C; Smith B; Maekawa S; Bodi I; Rogelj B; Al-Chalabi A; Hortobágyi T; Shaw CE
Acta Neuropathol; 2011 Dec; 122(6):691-702. PubMed ID: 22101323
[TBL] [Abstract][Full Text] [Related]
35. p62/SQSTM1 protects against cisplatin-induced oxidative stress in kidneys by mediating the cross talk between autophagy and the Keap1-Nrf2 signalling pathway.
Liao W; Wang Z; Fu Z; Ma H; Jiang M; Xu A; Zhang W
Free Radic Res; 2019 Jul; 53(7):800-814. PubMed ID: 31223046
[TBL] [Abstract][Full Text] [Related]
36. The tau tubulin kinases TTBK1/2 promote accumulation of pathological TDP-43.
Liachko NF; McMillan PJ; Strovas TJ; Loomis E; Greenup L; Murrell JR; Ghetti B; Raskind MA; Montine TJ; Bird TD; Leverenz JB; Kraemer BC
PLoS Genet; 2014 Dec; 10(12):e1004803. PubMed ID: 25473830
[TBL] [Abstract][Full Text] [Related]
37. Exome sequencing in amyotrophic lateral sclerosis identifies risk genes and pathways.
Cirulli ET; Lasseigne BN; Petrovski S; Sapp PC; Dion PA; Leblond CS; Couthouis J; Lu YF; Wang Q; Krueger BJ; Ren Z; Keebler J; Han Y; Levy SE; Boone BE; Wimbish JR; Waite LL; Jones AL; Carulli JP; Day-Williams AG; Staropoli JF; Xin WW; Chesi A; Raphael AR; McKenna-Yasek D; Cady J; Vianney de Jong JM; Kenna KP; Smith BN; Topp S; Miller J; Gkazi A; ; Al-Chalabi A; van den Berg LH; Veldink J; Silani V; Ticozzi N; Shaw CE; Baloh RH; Appel S; Simpson E; Lagier-Tourenne C; Pulst SM; Gibson S; Trojanowski JQ; Elman L; McCluskey L; Grossman M; Shneider NA; Chung WK; Ravits JM; Glass JD; Sims KB; Van Deerlin VM; Maniatis T; Hayes SD; Ordureau A; Swarup S; Landers J; Baas F; Allen AS; Bedlack RS; Harper JW; Gitler AD; Rouleau GA; Brown R; Harms MB; Cooper GM; Harris T; Myers RM; Goldstein DB
Science; 2015 Mar; 347(6229):1436-41. PubMed ID: 25700176
[TBL] [Abstract][Full Text] [Related]
38. FIP200 controls the TBK1 activation threshold at SQSTM1/p62-positive condensates.
Schlütermann D; Berleth N; Deitersen J; Wallot-Hieke N; Friesen O; Wu W; Stuhldreier F; Sun Y; Berning L; Friedrich A; Mendiburo MJ; Peter C; Wiek C; Hanenberg H; Stefanski A; Stühler K; Stork B
Sci Rep; 2021 Jul; 11(1):13863. PubMed ID: 34226595
[TBL] [Abstract][Full Text] [Related]
39. Negative Regulation of the Keap1-Nrf2 Pathway by a p62/Sqstm1 Splicing Variant.
Kageyama S; Saito T; Obata M; Koide RH; Ichimura Y; Komatsu M
Mol Cell Biol; 2018 Apr; 38(7):. PubMed ID: 29339380
[TBL] [Abstract][Full Text] [Related]
40. A glaucoma- and ALS-associated mutant of OPTN induces neuronal cell death dependent on Tbk1 activity, autophagy and ER stress.
Medchalmi S; Tare P; Sayyad Z; Swarup G
FEBS J; 2021 Aug; 288(15):4576-4595. PubMed ID: 33548116
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
