BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

409 related articles for article (PubMed ID: 32837681)

  • 1. A history of the roles of cytochrome P450 enzymes in the toxicity of drugs.
    Guengerich FP
    Toxicol Res; 2021 Jan; 37(1):1-23. PubMed ID: 32837681
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Roles of cytochrome P450 enzymes in pharmacology and toxicology: Past, present, and future.
    Guengerich FP
    Adv Pharmacol; 2022; 95():1-47. PubMed ID: 35953152
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A passion for P450s (rememberances of the early history of research on cytochrome P450).
    Estabrook RW
    Drug Metab Dispos; 2003 Dec; 31(12):1461-73. PubMed ID: 14625342
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Cytochrome P450s and other enzymes in drug metabolism and toxicity.
    Guengerich FP
    AAPS J; 2006 Mar; 8(1):E101-11. PubMed ID: 16584116
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Cytochrome p450 and chemical toxicology.
    Guengerich FP
    Chem Res Toxicol; 2008 Jan; 21(1):70-83. PubMed ID: 18052394
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Inhibition of Cytochrome P450 Enzymes by Drugs-Molecular Basis and Practical Applications.
    Guengerich FP
    Biomol Ther (Seoul); 2022 Jan; 30(1):1-18. PubMed ID: 34475272
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Role of cytochrome P450 enzymes in drug-drug interactions.
    Guengerich FP
    Adv Pharmacol; 1997; 43():7-35. PubMed ID: 9342171
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mechanism-based inactivation of human cytochromes p450s: experimental characterization, reactive intermediates, and clinical implications.
    Hollenberg PF; Kent UM; Bumpus NN
    Chem Res Toxicol; 2008 Jan; 21(1):189-205. PubMed ID: 18052110
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibition and induction of cytochrome P450 and the clinical implications.
    Lin JH; Lu AY
    Clin Pharmacokinet; 1998 Nov; 35(5):361-90. PubMed ID: 9839089
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The role of cytochrome P450 in cytotoxic bioactivation: future therapeutic directions.
    Rooney PH; Telfer C; McFadyen MC; Melvin WT; Murray GI
    Curr Cancer Drug Targets; 2004 May; 4(3):257-65. PubMed ID: 15134533
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cytochrome P450: what have we learned and what are the future issues?
    Guengerich FP
    Drug Metab Rev; 2004 May; 36(2):159-97. PubMed ID: 15237850
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cytochrome P450. Mechanisms of action and clinical implications.
    Williams MT
    J Fla Med Assoc; 1992 Jun; 79(6):405-8. PubMed ID: 1640215
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Drug Metabolism: A Half-Century Plus of Progress, Continued Needs, and New Opportunities.
    Guengerich FP
    Drug Metab Dispos; 2023 Jan; 51(1):99-104. PubMed ID: 35868640
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A novel cytochrome P450 mono-oxygenase from Streptomyces platensis resembles activities of human drug metabolizing P450s.
    Worsch A; Eggimann FK; Girhard M; von Bühler CJ; Tieves F; Czaja R; Vogel A; Grumaz C; Sohn K; Lütz S; Kittelmann M; Urlacher VB
    Biotechnol Bioeng; 2018 Sep; 115(9):2156-2166. PubMed ID: 29943426
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Reaction Phenotyping of Low-Turnover Compounds in Long-Term Hepatocyte Cultures Through Persistent Selective Inhibition of Cytochromes P450.
    Smith S; Lyman M; Ma B; Tweedie D; Menzel K
    Drug Metab Dispos; 2021 Nov; 49(11):995-1002. PubMed ID: 34407991
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Application of cytochrome P450 reactivity on the characterization of chemical compounds and its association with repeated-dose toxicity.
    Watanabe M; Sasaki T; Takeshita JI; Kushida M; Shimizu Y; Oki H; Kitsunai Y; Nakayama H; Saruhashi H; Ogura R; Shizu R; Hosaka T; Yoshinari K
    Toxicol Appl Pharmacol; 2020 Feb; 388():114854. PubMed ID: 31836524
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Designing better drugs: predicting cytochrome P450 metabolism.
    de Groot MJ
    Drug Discov Today; 2006 Jul; 11(13-14):601-6. PubMed ID: 16793528
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mechanism-based inactivation of cytochrome P450 enzymes: chemical mechanisms, structure-activity relationships and relationship to clinical drug-drug interactions and idiosyncratic adverse drug reactions.
    Kalgutkar AS; Obach RS; Maurer TS
    Curr Drug Metab; 2007 Jun; 8(5):407-47. PubMed ID: 17584015
    [TBL] [Abstract][Full Text] [Related]  

  • 19. In vitro inhibitory mechanisms and molecular docking of 1'-S-1'-acetoxychavicol acetate on human cytochrome P450 enzymes.
    Haque AKMM; Leong KH; Lo YL; Awang K; Nagoor NH
    Phytomedicine; 2017 Jul; 31():1-9. PubMed ID: 28606510
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Cytochrome P450 research and
    Guengerich FP
    J Biol Chem; 2019 Feb; 294(5):1671-1680. PubMed ID: 29871932
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 21.