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28. Inhibition of JAK-STAT Signaling Suppresses Pathogenic Immune Responses in Medium and Large Vessel Vasculitis. Zhang H; Watanabe R; Berry GJ; Tian L; Goronzy JJ; Weyand CM Circulation; 2018 May; 137(18):1934-1948. PubMed ID: 29254929 [TBL] [Abstract][Full Text] [Related]
29. HOXA9 Cooperates with Activated JAK/STAT Signaling to Drive Leukemia Development. de Bock CE; Demeyer S; Degryse S; Verbeke D; Sweron B; Gielen O; Vandepoel R; Vicente C; Vanden Bempt M; Dagklis A; Geerdens E; Bornschein S; Gijsbers R; Soulier J; Meijerink JP; Heinäniemi M; Teppo S; Bouvy-Liivrand M; Lohi O; Radaelli E; Cools J Cancer Discov; 2018 May; 8(5):616-631. PubMed ID: 29496663 [TBL] [Abstract][Full Text] [Related]
30. [Ruxolitinib combined with venetoclax and azacitidine in the treatment of refractory T-ALL patients with JAK1, JAK3, and STAT5B gene mutations: a case report and literature review]. Xu PP; Zhou T; Xu YY; Peng MX; Du Y; Xie T; Yang YG; Ouyang J; Chen B Zhonghua Xue Ye Xue Za Zhi; 2024 Sep; 45(9):872-875. PubMed ID: 39414615 [TBL] [Abstract][Full Text] [Related]
31. Evaluation of JAK3 Biology in Autoimmune Disease Using a Highly Selective, Irreversible JAK3 Inhibitor. Elwood F; Witter DJ; Piesvaux J; Kraybill B; Bays N; Alpert C; Goldenblatt P; Qu Y; Ivanovska I; Lee HH; Chiu CS; Tang H; Scott ME; Deshmukh SV; Zielstorff M; Byford A; Chakravarthy K; Dorosh L; Rivkin A; Klappenbach J; Pan BS; Kariv I; Dinsmore C; Slipetz D; Dandliker PJ J Pharmacol Exp Ther; 2017 May; 361(2):229-244. PubMed ID: 28193636 [TBL] [Abstract][Full Text] [Related]
32. Mutant JAK3 signaling is increased by loss of wild-type JAK3 or by acquisition of secondary JAK3 mutations in T-ALL. Degryse S; Bornschein S; de Bock CE; Leroy E; Vanden Bempt M; Demeyer S; Jacobs K; Geerdens E; Gielen O; Soulier J; Harrison CJ; Constantinescu SN; Cools J Blood; 2018 Jan; 131(4):421-425. PubMed ID: 29187379 [TBL] [Abstract][Full Text] [Related]
33. New MLLT10 gene recombinations in pediatric T-acute lymphoblastic leukemia. Brandimarte L; Pierini V; Di Giacomo D; Borga C; Nozza F; Gorello P; Giordan M; Cazzaniga G; Te Kronnie G; La Starza R; Mecucci C Blood; 2013 Jun; 121(25):5064-7. PubMed ID: 23673860 [TBL] [Abstract][Full Text] [Related]
35. JAK1 Pseudokinase V666G Mutant Dominantly Impairs JAK3 Phosphorylation and IL-2 Signaling. Grant AH; Rodriguez AC; Rodriguez Moncivais OJ; Sun S; Li L; Mohl JE; Leung MY; Kirken RA; Rodriguez G Int J Mol Sci; 2023 Apr; 24(7):. PubMed ID: 37047778 [TBL] [Abstract][Full Text] [Related]
36. A unique case of refractory primary mediastinal B-cell lymphoma with JAK3 mutation and the role for targeted therapy. Hanna DM; Fellowes A; Vedururu R; Mechinaud F; Hansford JR Haematologica; 2014 Sep; 99(9):e156-8. PubMed ID: 24837469 [No Abstract] [Full Text] [Related]
37. Identification of a homozygous JAK3 V674A mutation caused by acquired uniparental disomy in a relapsed early T-cell precursor ALL patient. Kawashima-Goto S; Imamura T; Seki M; Kato M; Yoshida K; Sugimoto A; Kaneda D; Fujiki A; Miyachi M; Nakatani T; Osone S; Ishida H; Taki T; Takita J; Shiraishi Y; Chiba K; Tanaka H; Miyano S; Ogawa S; Hosoi H Int J Hematol; 2015 Apr; 101(4):411-6. PubMed ID: 25430085 [TBL] [Abstract][Full Text] [Related]
38. Jak1 has a dominant role over Jak3 in signal transduction through γc-containing cytokine receptors. Haan C; Rolvering C; Raulf F; Kapp M; Drückes P; Thoma G; Behrmann I; Zerwes HG Chem Biol; 2011 Mar; 18(3):314-23. PubMed ID: 21439476 [TBL] [Abstract][Full Text] [Related]
39. Mutant JAK3 phosphoproteomic profiling predicts synergism between JAK3 inhibitors and MEK/BCL2 inhibitors for the treatment of T-cell acute lymphoblastic leukemia. Degryse S; de Bock CE; Demeyer S; Govaerts I; Bornschein S; Verbeke D; Jacobs K; Binos S; Skerrett-Byrne DA; Murray HC; Verrills NM; Van Vlierberghe P; Cools J; Dun MD Leukemia; 2018 Mar; 32(3):788-800. PubMed ID: 28852199 [TBL] [Abstract][Full Text] [Related]
40. Driver mutations in Janus kinases in a mouse model of B-cell leukemia induced by deletion of PU.1 and Spi-B. Batista CR; Lim M; Laramée AS; Abu-Sardanah F; Xu LS; Hossain R; Bell GI; Hess DA; DeKoter RP Blood Adv; 2018 Nov; 2(21):2798-2810. PubMed ID: 30355579 [TBL] [Abstract][Full Text] [Related] [Previous] [Next] [New Search]