BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

150 related articles for article (PubMed ID: 32846985)

  • 1. Sephin1 Protects Neurons against Excitotoxicity Independently of the Integrated Stress Response.
    Ruiz A; Zuazo J; Ortiz-Sanz C; Luchena C; Matute C; Alberdi E
    Int J Mol Sci; 2020 Aug; 21(17):. PubMed ID: 32846985
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Alpha-lipoic acid protects against cadmium-induced neuronal injury by inhibiting the endoplasmic reticulum stress eIF2α-ATF4 pathway in rat cortical neurons in vitro and in vivo.
    Yuan Y; Yang J; Chen J; Zhao S; Wang T; Zou H; Wang Y; Gu J; Liu X; Bian J; Liu Z
    Toxicology; 2019 Feb; 414():1-13. PubMed ID: 30605698
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Guanabenz ameliorates disease in vanishing white matter mice in contrast to sephin1.
    Witkamp D; Oudejans E; Hu-A-Ng GV; Hoogterp L; Krzywańska AM; Žnidaršič M; Marinus K; de Veij Mestdagh CF; Bartelink I; Bugiani M; van der Knaap MS; Abbink TEM
    Ann Clin Transl Neurol; 2022 Aug; 9(8):1147-1162. PubMed ID: 35778832
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Sephin1 Reduces Prion Infection in Prion-Infected Cells and Animal Model.
    Thapa S; Abdelaziz DH; Abdulrahman BA; Schatzl HM
    Mol Neurobiol; 2020 May; 57(5):2206-2219. PubMed ID: 31981074
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Sephin1, which prolongs the integrated stress response, is a promising therapeutic for multiple sclerosis.
    Chen Y; Podojil JR; Kunjamma RB; Jones J; Weiner M; Lin W; Miller SD; Popko B
    Brain; 2019 Feb; 142(2):344-361. PubMed ID: 30657878
    [TBL] [Abstract][Full Text] [Related]  

  • 6. PPP1R15A-mediated dephosphorylation of eIF2α is unaffected by Sephin1 or Guanabenz.
    Crespillo-Casado A; Chambers JE; Fischer PM; Marciniak SJ; Ron D
    Elife; 2017 Apr; 6():. PubMed ID: 28447936
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A Sephin1-insensitive tripartite holophosphatase dephosphorylates translation initiation factor 2α.
    Crespillo-Casado A; Claes Z; Choy MS; Peti W; Bollen M; Ron D
    J Biol Chem; 2018 May; 293(20):7766-7776. PubMed ID: 29618508
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Guanabenz interferes with ER stress and exerts protective effects in cardiac myocytes.
    Neuber C; Uebeler J; Schulze T; Sotoud H; El-Armouche A; Eschenhagen T
    PLoS One; 2014; 9(6):e98893. PubMed ID: 24892553
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Evaluation of the Antiviral Activity of Sephin1 Treatment and Its Consequences on eIF2α Phosphorylation in Response to Viral Infections.
    Fusade-Boyer M; Dupré G; Bessière P; Khiar S; Quentin-Froignant C; Beck C; Lecollinet S; Rameix-Welti MA; Eléouët JF; Tangy F; Lajoie B; Bertagnoli S; Vidalain PO; Gallardo F; Volmer R
    Front Immunol; 2019; 10():134. PubMed ID: 30809223
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Guanabenz delays the onset of disease symptoms, extends lifespan, improves motor performance and attenuates motor neuron loss in the SOD1 G93A mouse model of amyotrophic lateral sclerosis.
    Jiang HQ; Ren M; Jiang HZ; Wang J; Zhang J; Yin X; Wang SY; Qi Y; Wang XD; Feng HL
    Neuroscience; 2014 Sep; 277():132-8. PubMed ID: 24699224
    [TBL] [Abstract][Full Text] [Related]  

  • 11. In silico screening of GMQ-like compounds reveals guanabenz and sephin1 as new allosteric modulators of acid-sensing ion channel 3.
    Callejo G; Pattison LA; Greenhalgh JC; Chakrabarti S; Andreopoulou E; Hockley JRF; Smith ESJ; Rahman T
    Biochem Pharmacol; 2020 Apr; 174():113834. PubMed ID: 32027884
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Guanabenz Sensitizes Pancreatic β Cells to Lipotoxic Endoplasmic Reticulum Stress and Apoptosis.
    Abdulkarim B; Hernangomez M; Igoillo-Esteve M; Cunha DA; Marselli L; Marchetti P; Ladriere L; Cnop M
    Endocrinology; 2017 Jun; 158(6):1659-1670. PubMed ID: 28323924
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Guanabenz Treatment Accelerates Disease in a Mutant SOD1 Mouse Model of ALS.
    Vieira FG; Ping Q; Moreno AJ; Kidd JD; Thompson K; Jiang B; Lincecum JM; Wang MZ; De Zutter GS; Tassinari VR; Levine B; Hatzipetros T; Gill A; Perrin S
    PLoS One; 2015; 10(8):e0135570. PubMed ID: 26288094
    [TBL] [Abstract][Full Text] [Related]  

  • 14. N-methyl-D-aspartate and TrkB receptors protect neurons against glutamate excitotoxicity through an extracellular signal-regulated kinase pathway.
    Zhu D; Wu X; Strauss KI; Lipsky RH; Qureshi Z; Terhakopian A; Novelli A; Banaudha K; Marini AM
    J Neurosci Res; 2005 Apr; 80(1):104-13. PubMed ID: 15744743
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Protection by cholesterol-extracting cyclodextrins: a role for N-methyl-D-aspartate receptor redistribution.
    Abulrob A; Tauskela JS; Mealing G; Brunette E; Faid K; Stanimirovic D
    J Neurochem; 2005 Mar; 92(6):1477-86. PubMed ID: 15748165
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Phenformin suppresses calcium responses to glutamate and protects hippocampal neurons against excitotoxicity.
    Lee J; Chan SL; Lu C; Lane MA; Mattson MP
    Exp Neurol; 2002 May; 175(1):161-7. PubMed ID: 12009768
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Ghrelin suppresses tunicamycin- or thapsigargin-triggered endoplasmic reticulum stress-mediated apoptosis in primary cultured rat cortical neuronal cells.
    Chung H; Chung HY; Bae CW; Kim CJ; Park S
    Endocr J; 2011; 58(5):409-20. PubMed ID: 21490406
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Protein misfolding, amyotrophic lateral sclerosis and guanabenz: protocol for a phase II RCT with futility design (ProMISe trial).
    Bella ED; Tramacere I; Antonini G; Borghero G; Capasso M; Caponnetto C; Chiò A; Corbo M; Eleopra R; Filosto M; Giannini F; Granieri E; Bella V; Lunetta C; Mandrioli J; Mazzini L; Messina S; Monsurrò MR; Mora G; Riva N; Rizzi R; Siciliano G; Silani V; Simone I; Sorarù G; Volanti P; Lauria G
    BMJ Open; 2017 Aug; 7(8):e015434. PubMed ID: 28801400
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Rg1 in combination with mannitol protects neurons against glutamate-induced ER stress via the PERK-eIF2 α-ATF4 signaling pathway.
    Gu Y; Ren K; Wang L; Jiang C; Yao Q
    Life Sci; 2020 Dec; 263():118559. PubMed ID: 33038374
    [TBL] [Abstract][Full Text] [Related]  

  • 20. ATF4-mediated transcriptional regulation protects against β-cell loss during endoplasmic reticulum stress in a mouse model.
    Kitakaze K; Oyadomari M; Zhang J; Hamada Y; Takenouchi Y; Tsuboi K; Inagaki M; Tachikawa M; Fujitani Y; Okamoto Y; Oyadomari S
    Mol Metab; 2021 Dec; 54():101338. PubMed ID: 34547510
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.