BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

249 related articles for article (PubMed ID: 32850008)

  • 1. Obinutuzumab (GA101) vs. rituximab significantly enhances cell death, antibody-dependent cytotoxicity and improves overall survival against CD20+ primary mediastinal B-cell lymphoma (PMBL) in a xenograft NOD-scid IL2Rgnull (NSG) mouse model: a potential targeted agent in the treatment of PMBL.
    Chu Y; Awasthi A; Lee S; Edani D; Yin C; Hochberg J; Shah T; Chung TH; Ayello J; van de Ven C; Klein C; Lee D; Cairo MS
    Oncotarget; 2020 Aug; 11(32):3035-3047. PubMed ID: 32850008
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Obinutuzumab (GA101) compared to rituximab significantly enhances cell death and antibody-dependent cytotoxicity and improves overall survival against CD20(+) rituximab-sensitive/-resistant Burkitt lymphoma (BL) and precursor B-acute lymphoblastic leukaemia (pre-B-ALL): potential targeted therapy in patients with poor risk CD20(+) BL and pre-B-ALL.
    Awasthi A; Ayello J; Van de Ven C; Elmacken M; Sabulski A; Barth MJ; Czuczman MS; Islam H; Klein C; Cairo MS
    Br J Haematol; 2015 Dec; 171(5):763-75. PubMed ID: 26471982
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Antitumour activity of the glycoengineered type II anti-CD20 antibody obinutuzumab (GA101) in combination with the MDM2-selective antagonist idasanutlin (RG7388).
    Herting F; Herter S; Friess T; Muth G; Bacac M; Sulcova J; Umana P; Dangl M; Klein C
    Eur J Haematol; 2016 Nov; 97(5):461-470. PubMed ID: 26993060
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Follicular lymphoma: in vitro effects of combining lymphokine-activated killer (LAK) cell-induced cytotoxicity and rituximab- and obinutuzumab-dependent cellular cytotoxicity (ADCC) activity.
    García-Muñoz R; López-Díaz-de-Cerio A; Feliu J; Panizo A; Giraldo P; Rodríguez-Calvillo M; Grande C; Pena E; Olave M; Panizo C; Inogés S
    Immunol Res; 2016 Apr; 64(2):548-57. PubMed ID: 26659089
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Preclinical activity of the type II CD20 antibody GA101 (obinutuzumab) compared with rituximab and ofatumumab in vitro and in xenograft models.
    Herter S; Herting F; Mundigl O; Waldhauer I; Weinzierl T; Fauti T; Muth G; Ziegler-Landesberger D; Van Puijenbroek E; Lang S; Duong MN; Reslan L; Gerdes CA; Friess T; Baer U; Burtscher H; Weidner M; Dumontet C; Umana P; Niederfellner G; Bacac M; Klein C
    Mol Cancer Ther; 2013 Oct; 12(10):2031-42. PubMed ID: 23873847
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Enhanced anti-tumor activity of the glycoengineered type II CD20 antibody obinutuzumab (GA101) in combination with chemotherapy in xenograft models of human lymphoma.
    Herting F; Friess T; Bader S; Muth G; Hölzlwimmer G; Rieder N; Umana P; Klein C
    Leuk Lymphoma; 2014 Sep; 55(9):2151-5160. PubMed ID: 24304419
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A comparative global phosphoproteomics analysis of obinutuzumab (GA101) versus rituximab (RTX) against RTX sensitive and resistant Burkitt lymphoma (BL) demonstrates differential phosphorylation of signaling pathway proteins after treatment.
    Awasthi A; Rolland DCM; Ayello J; van de Ven C; Basrur V; Conlon K; Fermin D; Barth MJ; Klein C; Elenitoba-Johnson KSJ; Lim MS; Cairo MS
    Oncotarget; 2017 Dec; 8(69):113895-113909. PubMed ID: 29371955
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Obinutuzumab in hematologic malignancies: lessons learned to date.
    Illidge T; Klein C; Sehn LH; Davies A; Salles G; Cartron G
    Cancer Treat Rev; 2015 Nov; 41(9):784-92. PubMed ID: 26190254
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Anti-tumor efficacy study of the Bruton's tyrosine kinase (BTK) inhibitor, ONO/GS-4059, in combination with the glycoengineered type II anti-CD20 monoclonal antibody obinutuzumab (GA101) demonstrates superior in vivo efficacy compared to ONO/GS-4059 in combination with rituximab.
    Yasuhiro T; Sawada W; Klein C; Kozaki R; Hotta S; Yoshizawa T
    Leuk Lymphoma; 2017 Mar; 58(3):699-707. PubMed ID: 27684575
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Obinutuzumab (GA101) for the treatment of chronic lymphocytic leukemia and other B-cell non-hodgkin's lymphomas: a glycoengineered type II CD20 antibody.
    Goede V; Klein C; Stilgenbauer S
    Oncol Res Treat; 2015; 38(4):185-92. PubMed ID: 25877943
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A Review of Obinutuzumab (GA101), a Novel Type II Anti-CD20 Monoclonal Antibody, for the Treatment of Patients with B-Cell Malignancies.
    Tobinai K; Klein C; Oya N; Fingerle-Rowson G
    Adv Ther; 2017 Feb; 34(2):324-356. PubMed ID: 28004361
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Randomized Phase II Trial Comparing Obinutuzumab (GA101) With Rituximab in Patients With Relapsed CD20+ Indolent B-Cell Non-Hodgkin Lymphoma: Final Analysis of the GAUSS Study.
    Sehn LH; Goy A; Offner FC; Martinelli G; Caballero MD; Gadeberg O; Baetz T; Zelenetz AD; Gaidano G; Fayad LE; Buckstein R; Friedberg JW; Crump M; Jaksic B; Zinzani PL; Padmanabhan Iyer S; Sahin D; Chai A; Fingerle-Rowson G; Press OW
    J Clin Oncol; 2015 Oct; 33(30):3467-74. PubMed ID: 26282650
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Preclinical studies on the mechanism of action and the anti-lymphoma activity of the novel anti-CD20 antibody GA101.
    Dalle S; Reslan L; Besseyre de Horts T; Herveau S; Herting F; Plesa A; Friess T; Umana P; Klein C; Dumontet C
    Mol Cancer Ther; 2011 Jan; 10(1):178-85. PubMed ID: 21220500
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Obinutuzumab: a new class of anti-CD20 monoclonal antibody.
    Gagez AL; Cartron G
    Curr Opin Oncol; 2014 Sep; 26(5):484-91. PubMed ID: 25014645
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Novel cytokine-antibody fusion protein, N-820, to enhance the functions of ex vivo expanded natural killer cells against Burkitt lymphoma.
    Chu Y; Nayyar G; Kham Su N; Rosenblum JM; Soon-Shiong P; Lee J; Safrit JT; Barth M; Lee D; Cairo MS
    J Immunother Cancer; 2020 Oct; 8(2):. PubMed ID: 33109629
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Determination of optimum vitamin D3 levels for NK cell-mediated rituximab- and obinutuzumab-dependent cellular cytotoxicity.
    Neumann F; Acker F; Schormann C; Pfreundschuh M; Bittenbring JT
    Cancer Immunol Immunother; 2018 Nov; 67(11):1709-1718. PubMed ID: 30132083
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Obinutuzumab for the treatment of lymphoproliferative disorders.
    Owen C; Stewart DA
    Expert Opin Biol Ther; 2012 Mar; 12(3):343-51. PubMed ID: 22283718
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Antigenic modulation limits the effector cell mechanisms employed by type I anti-CD20 monoclonal antibodies.
    Tipton TR; Roghanian A; Oldham RJ; Carter MJ; Cox KL; Mockridge CI; French RR; Dahal LN; Duriez PJ; Hargreaves PG; Cragg MS; Beers SA
    Blood; 2015 Mar; 125(12):1901-9. PubMed ID: 25631769
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The IL-15-Based ALT-803 Complex Enhances FcγRIIIa-Triggered NK Cell Responses and In Vivo Clearance of B Cell Lymphomas.
    Rosario M; Liu B; Kong L; Collins LI; Schneider SE; Chen X; Han K; Jeng EK; Rhode PR; Leong JW; Schappe T; Jewell BA; Keppel CR; Shah K; Hess B; Romee R; Piwnica-Worms DR; Cashen AF; Bartlett NL; Wong HC; Fehniger TA
    Clin Cancer Res; 2016 Feb; 22(3):596-608. PubMed ID: 26423796
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Glycoengineered CD20 antibody obinutuzumab activates neutrophils and mediates phagocytosis through CD16B more efficiently than rituximab.
    Golay J; Da Roit F; Bologna L; Ferrara C; Leusen JH; Rambaldi A; Klein C; Introna M
    Blood; 2013 Nov; 122(20):3482-91. PubMed ID: 24106207
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.