299 related articles for article (PubMed ID: 32853409)
1. LRRK2 and Rab10 coordinate macropinocytosis to mediate immunological responses in phagocytes.
Liu Z; Xu E; Zhao HT; Cole T; West AB
EMBO J; 2020 Oct; 39(20):e104862. PubMed ID: 32853409
[TBL] [Abstract][Full Text] [Related]
2. The Parkinson's disease VPS35[D620N] mutation enhances LRRK2-mediated Rab protein phosphorylation in mouse and human.
Mir R; Tonelli F; Lis P; Macartney T; Polinski NK; Martinez TN; Chou MY; Howden AJM; König T; Hotzy C; Milenkovic I; Brücke T; Zimprich A; Sammler E; Alessi DR
Biochem J; 2018 Jun; 475(11):1861-1883. PubMed ID: 29743203
[TBL] [Abstract][Full Text] [Related]
3. LRRK2 Is Recruited to Phagosomes and Co-recruits RAB8 and RAB10 in Human Pluripotent Stem Cell-Derived Macrophages.
Lee H; Flynn R; Sharma I; Haberman E; Carling PJ; Nicholls FJ; Stegmann M; Vowles J; Haenseler W; Wade-Martins R; James WS; Cowley SA
Stem Cell Reports; 2020 May; 14(5):940-955. PubMed ID: 32359446
[TBL] [Abstract][Full Text] [Related]
4. Distinct Roles for RAB10 and RAB29 in Pathogenic LRRK2-Mediated Endolysosomal Trafficking Alterations.
Rivero-Ríos P; Romo-Lozano M; Fernández B; Fdez E; Hilfiker S
Cells; 2020 Jul; 9(7):. PubMed ID: 32709066
[TBL] [Abstract][Full Text] [Related]
5. Single molecule array measures of LRRK2 kinase activity in serum link Parkinson's disease severity to peripheral inflammation.
Yuan Y; Li H; Sreeram K; Malankhanova T; Boddu R; Strader S; Chang A; Bryant N; Yacoubian TA; Standaert DG; Erb M; Moore DJ; Sanders LH; Lutz MW; Velmeshev D; West AB
Mol Neurodegener; 2024 Jun; 19(1):47. PubMed ID: 38862989
[TBL] [Abstract][Full Text] [Related]
6. Development of phospho-specific Rab protein antibodies to monitor
Lis P; Burel S; Steger M; Mann M; Brown F; Diez F; Tonelli F; Holton JL; Ho PW; Ho SL; Chou MY; Polinski NK; Martinez TN; Davies P; Alessi DR
Biochem J; 2018 Jan; 475(1):1-22. PubMed ID: 29127256
[TBL] [Abstract][Full Text] [Related]
7. Lysosomal positioning regulates Rab10 phosphorylation at LRRK2
Kluss JH; Beilina A; Williamson CD; Lewis PA; Cookson MR; Bonet-Ponce L
Proc Natl Acad Sci U S A; 2022 Oct; 119(43):e2205492119. PubMed ID: 36256825
[TBL] [Abstract][Full Text] [Related]
8. Pathological α-synuclein recruits LRRK2 expressing pro-inflammatory monocytes to the brain.
Xu E; Boddu R; Abdelmotilib HA; Sokratian A; Kelly K; Liu Z; Bryant N; Chandra S; Carlisle SM; Lefkowitz EJ; Harms AS; Benveniste EN; Yacoubian TA; Volpicelli-Daley LA; Standaert DG; West AB
Mol Neurodegener; 2022 Jan; 17(1):7. PubMed ID: 35012605
[TBL] [Abstract][Full Text] [Related]
9. Phos-tag analysis of Rab10 phosphorylation by LRRK2: a powerful assay for assessing kinase function and inhibitors.
Ito G; Katsemonova K; Tonelli F; Lis P; Baptista MA; Shpiro N; Duddy G; Wilson S; Ho PW; Ho SL; Reith AD; Alessi DR
Biochem J; 2016 Sep; 473(17):2671-85. PubMed ID: 27474410
[TBL] [Abstract][Full Text] [Related]
10. Endogenous Rab29 does not impact basal or stimulated LRRK2 pathway activity.
Kalogeropulou AF; Freemantle JB; Lis P; Vides EG; Polinski NK; Alessi DR
Biochem J; 2020 Nov; 477(22):4397-4423. PubMed ID: 33135724
[TBL] [Abstract][Full Text] [Related]
11. LRRK2 and its substrate Rab GTPases are sequentially targeted onto stressed lysosomes and maintain their homeostasis.
Eguchi T; Kuwahara T; Sakurai M; Komori T; Fujimoto T; Ito G; Yoshimura SI; Harada A; Fukuda M; Koike M; Iwatsubo T
Proc Natl Acad Sci U S A; 2018 Sep; 115(39):E9115-E9124. PubMed ID: 30209220
[TBL] [Abstract][Full Text] [Related]
12. Directing LRRK2 to membranes of the endolysosomal pathway triggers RAB phosphorylation and JIP4 recruitment.
Kluss JH; Bonet-Ponce L; Lewis PA; Cookson MR
Neurobiol Dis; 2022 Aug; 170():105769. PubMed ID: 35580815
[TBL] [Abstract][Full Text] [Related]
13. Elevated Urinary Rab10 Phosphorylation in Idiopathic Parkinson Disease.
Wang S; Unnithan S; Bryant N; Chang A; Rosenthal LS; Pantelyat A; Dawson TM; Al-Khalidi HR; West AB
Mov Disord; 2022 Jul; 37(7):1454-1464. PubMed ID: 35521944
[TBL] [Abstract][Full Text] [Related]
14. Systematic proteomic analysis of LRRK2-mediated Rab GTPase phosphorylation establishes a connection to ciliogenesis.
Steger M; Diez F; Dhekne HS; Lis P; Nirujogi RS; Karayel O; Tonelli F; Martinez TN; Lorentzen E; Pfeffer SR; Alessi DR; Mann M
Elife; 2017 Nov; 6():. PubMed ID: 29125462
[TBL] [Abstract][Full Text] [Related]
15. Genetic background influences LRRK2-mediated Rab phosphorylation in the rat brain.
Kelly K; Chang A; Hastings L; Abdelmotilib H; West AB
Brain Res; 2021 May; 1759():147372. PubMed ID: 33600829
[TBL] [Abstract][Full Text] [Related]
16. RAB8, RAB10 and RILPL1 contribute to both LRRK2 kinase-mediated centrosomal cohesion and ciliogenesis deficits.
Lara Ordónez AJ; Fernández B; Fdez E; Romo-Lozano M; Madero-Pérez J; Lobbestael E; Baekelandt V; Aiastui A; López de Munaín A; Melrose HL; Civiero L; Hilfiker S
Hum Mol Genet; 2019 Nov; 28(21):3552-3568. PubMed ID: 31428781
[TBL] [Abstract][Full Text] [Related]
17. Roles of lysosomotropic agents on LRRK2 activation and Rab10 phosphorylation.
Kuwahara T; Funakawa K; Komori T; Sakurai M; Yoshii G; Eguchi T; Fukuda M; Iwatsubo T
Neurobiol Dis; 2020 Nov; 145():105081. PubMed ID: 32919031
[TBL] [Abstract][Full Text] [Related]
18. Rab10-Positive Tubular Structures Represent a Novel Endocytic Pathway That Diverges From Canonical Macropinocytosis in RAW264 Macrophages.
Kawai K; Nishigaki A; Moriya S; Egami Y; Araki N
Front Immunol; 2021; 12():649600. PubMed ID: 34135890
[TBL] [Abstract][Full Text] [Related]
19. LRRK2 phosphorylates membrane-bound Rabs and is activated by GTP-bound Rab7L1 to promote recruitment to the trans-Golgi network.
Liu Z; Bryant N; Kumaran R; Beilina A; Abeliovich A; Cookson MR; West AB
Hum Mol Genet; 2018 Jan; 27(2):385-395. PubMed ID: 29177506
[TBL] [Abstract][Full Text] [Related]
20. Rab10 Phosphorylation Detection by LRRK2 Activity Using SDS-PAGE with a Phosphate-binding Tag.
Ito G; Tomita T
J Vis Exp; 2017 Dec; (130):. PubMed ID: 29286425
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
