BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

458 related articles for article (PubMed ID: 32859627)

  • 1. Whole-transcriptome Analysis of Fully Viable Energy Efficient Glycolytic-null Cancer Cells Established by Double Genetic Knockout of Lactate Dehydrogenase A/B or Glucose-6-Phosphate Isomerase.
    Mazzio E; Badisa R; Mack N; Cassim S; Zdralevic M; Pouyssegur J; Soliman KFA
    Cancer Genomics Proteomics; 2020; 17(5):469-497. PubMed ID: 32859627
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Double genetic disruption of lactate dehydrogenases A and B is required to ablate the "Warburg effect" restricting tumor growth to oxidative metabolism.
    Ždralević M; Brand A; Di Ianni L; Dettmer K; Reinders J; Singer K; Peter K; Schnell A; Bruss C; Decking SM; Koehl G; Felipe-Abrio B; Durivault J; Bayer P; Evangelista M; O'Brien T; Oefner PJ; Renner K; Pouysségur J; Kreutz M
    J Biol Chem; 2018 Oct; 293(41):15947-15961. PubMed ID: 30158244
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Stable shRNA Silencing of Lactate Dehydrogenase A (LDHA) in Human MDA-MB-231 Breast Cancer Cells Fails to Alter Lactic Acid Production, Glycolytic Activity, ATP or Survival.
    Mack N; Mazzio EA; Bauer D; Flores-Rozas H; Soliman KF
    Anticancer Res; 2017 Mar; 37(3):1205-1212. PubMed ID: 28314283
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Metabolic Response to the Mitochondrial Toxin 1-Methyl-4-phenylpyridinium (MPP+) in LDH-A/B Double-knockout LS174T Colon Cancer Cells.
    Mack N; Mazzio E; Badisa R; Soliman KFA
    Cancer Genomics Proteomics; 2021; 18(3 Suppl):385-405. PubMed ID: 33994363
    [TBL] [Abstract][Full Text] [Related]  

  • 5. JMJD2A promotes the Warburg effect and nasopharyngeal carcinoma progression by transactivating LDHA expression.
    Su Y; Yu QH; Wang XY; Yu LP; Wang ZF; Cao YC; Li JD
    BMC Cancer; 2017 Jul; 17(1):477. PubMed ID: 28693517
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Triple Isozyme Lactic Acid Dehydrogenase Inhibition in Fully Viable MDA-MB-231 Cells Induces Cytostatic Effects That Are Not Reversed by Exogenous Lactic Acid.
    Mazzio E; Mack N; Badisa RB; Soliman KFA
    Biomolecules; 2021 Nov; 11(12):. PubMed ID: 34944395
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Lactate dehydrogenase A negatively regulated by miRNAs promotes aerobic glycolysis and is increased in colorectal cancer.
    Wang J; Wang H; Liu A; Fang C; Hao J; Wang Z
    Oncotarget; 2015 Aug; 6(23):19456-68. PubMed ID: 26062441
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The drs tumor suppressor regulates glucose metabolism via lactate dehydrogenase-B.
    Tambe Y; Hasebe M; Kim CJ; Yamamoto A; Inoue H
    Mol Carcinog; 2016 Jan; 55(1):52-63. PubMed ID: 25620379
    [TBL] [Abstract][Full Text] [Related]  

  • 9. 'Warburg effect' controls tumor growth, bacterial, viral infections and immunity - Genetic deconstruction and therapeutic perspectives.
    Pouysségur J; Marchiq I; Parks SK; Durivault J; Ždralević M; Vucetic M
    Semin Cancer Biol; 2022 Nov; 86(Pt 2):334-346. PubMed ID: 35820598
    [TBL] [Abstract][Full Text] [Related]  

  • 10. FOXM1 promotes the warburg effect and pancreatic cancer progression via transactivation of LDHA expression.
    Cui J; Shi M; Xie D; Wei D; Jia Z; Zheng S; Gao Y; Huang S; Xie K
    Clin Cancer Res; 2014 May; 20(10):2595-606. PubMed ID: 24634381
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Role of LDH in tumor glycolysis: Regulation of LDHA by small molecules for cancer therapeutics.
    Sharma D; Singh M; Rani R
    Semin Cancer Biol; 2022 Dec; 87():184-195. PubMed ID: 36371026
    [TBL] [Abstract][Full Text] [Related]  

  • 12. LDHA in Neuroblastoma Is Associated with Poor Outcome and Its Depletion Decreases Neuroblastoma Growth Independent of Aerobic Glycolysis.
    Dorneburg C; Fischer M; Barth TFE; Mueller-Klieser W; Hero B; Gecht J; Carter DR; de Preter K; Mayer B; Christner L; Speleman F; Marshall GM; Debatin KM; Beltinger C
    Clin Cancer Res; 2018 Nov; 24(22):5772-5783. PubMed ID: 29925504
    [No Abstract]   [Full Text] [Related]  

  • 13. Unappreciated Role of LDHA and LDHB to Control Apoptosis and Autophagy in Tumor Cells.
    Urbańska K; Orzechowski A
    Int J Mol Sci; 2019 Apr; 20(9):. PubMed ID: 31035592
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The Warburg effect as a therapeutic target for bladder cancers and intratumoral heterogeneity in associated molecular targets.
    Burns JE; Hurst CD; Knowles MA; Phillips RM; Allison SJ
    Cancer Sci; 2021 Sep; 112(9):3822-3834. PubMed ID: 34181805
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Decreased lactate dehydrogenase B expression enhances claudin 1-mediated hepatoma cell invasiveness via mitochondrial defects.
    Kim JH; Kim EL; Lee YK; Park CB; Kim BW; Wang HJ; Yoon CH; Lee SJ; Yoon G
    Exp Cell Res; 2011 May; 317(8):1108-18. PubMed ID: 21356207
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Fibroblast growth factor pathway promotes glycolysis by activating LDHA and suppressing LDHB in a STAT1-dependent manner in prostate cancer.
    Ye Y; Yang F; Gu Z; Li W; Yuan Y; Liu S; Zhou L; Han B; Zheng R; Cao Z
    J Transl Med; 2024 May; 22(1):474. PubMed ID: 38764020
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Aurora-A mediated phosphorylation of LDHB promotes glycolysis and tumor progression by relieving the substrate-inhibition effect.
    Cheng A; Zhang P; Wang B; Yang D; Duan X; Jiang Y; Xu T; Jiang Y; Shi J; Ding C; Wu G; Sang Z; Wu Q; Wang H; Wu M; Zhang Z; Pan X; Pan YY; Gao P; Zhang H; Zhou CZ; Guo J; Yang Z
    Nat Commun; 2019 Dec; 10(1):5566. PubMed ID: 31804482
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Protein kinase CK2 modulation of pyruvate kinase M isoforms augments the Warburg effect in cancer cells.
    Yang KM; Kim K
    J Cell Biochem; 2018 Nov; 119(10):8501-8510. PubMed ID: 30015359
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Disrupting glucose-6-phosphate isomerase fully suppresses the "Warburg effect" and activates OXPHOS with minimal impact on tumor growth except in hypoxia.
    de Padua MC; Delodi G; Vučetić M; Durivault J; Vial V; Bayer P; Noleto GR; Mazure NM; Ždralević M; Pouysségur J
    Oncotarget; 2017 Oct; 8(50):87623-87637. PubMed ID: 29152106
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Tyrosine phosphorylation of lactate dehydrogenase A is important for NADH/NAD(+) redox homeostasis in cancer cells.
    Fan J; Hitosugi T; Chung TW; Xie J; Ge Q; Gu TL; Polakiewicz RD; Chen GZ; Boggon TJ; Lonial S; Khuri FR; Kang S; Chen J
    Mol Cell Biol; 2011 Dec; 31(24):4938-50. PubMed ID: 21969607
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 23.