BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

243 related articles for article (PubMed ID: 32866776)

  • 21. Formation of dynamic gamma-H2AX domains along broken DNA strands is distinctly regulated by ATM and MDC1 and dependent upon H2AX densities in chromatin.
    Savic V; Yin B; Maas NL; Bredemeyer AL; Carpenter AC; Helmink BA; Yang-Iott KS; Sleckman BP; Bassing CH
    Mol Cell; 2009 May; 34(3):298-310. PubMed ID: 19450528
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Targeting protein for xenopus kinesin-like protein 2 (TPX2) regulates γ-histone 2AX (γ-H2AX) levels upon ionizing radiation.
    Neumayer G; Helfricht A; Shim SY; Le HT; Lundin C; Belzil C; Chansard M; Yu Y; Lees-Miller SP; Gruss OJ; van Attikum H; Helleday T; Nguyen MD
    J Biol Chem; 2012 Dec; 287(50):42206-22. PubMed ID: 23045526
    [TBL] [Abstract][Full Text] [Related]  

  • 23. DNA damage response mediators MDC1 and 53BP1: constitutive activation and aberrant loss in breast and lung cancer, but not in testicular germ cell tumours.
    Bartkova J; Horejsí Z; Sehested M; Nesland JM; Rajpert-De Meyts E; Skakkebaek NE; Stucki M; Jackson S; Lukas J; Bartek J
    Oncogene; 2007 Nov; 26(53):7414-22. PubMed ID: 17546051
    [TBL] [Abstract][Full Text] [Related]  

  • 24. DNA Damage Response-Independent Role for MDC1 in Maintaining Genomic Stability.
    Li Z; Shao C; Kong Y; Carlock C; Ahmad N; Liu X
    Mol Cell Biol; 2017 May; 37(9):. PubMed ID: 28193847
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Cep164 is a mediator protein required for the maintenance of genomic stability through modulation of MDC1, RPA, and CHK1.
    Sivasubramaniam S; Sun X; Pan YR; Wang S; Lee EY
    Genes Dev; 2008 Mar; 22(5):587-600. PubMed ID: 18283122
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Ataxia telangiectasia mutated activation by transcription- and topoisomerase I-induced DNA double-strand breaks.
    Sordet O; Redon CE; Guirouilh-Barbat J; Smith S; Solier S; Douarre C; Conti C; Nakamura AJ; Das BB; Nicolas E; Kohn KW; Bonner WM; Pommier Y
    EMBO Rep; 2009 Aug; 10(8):887-93. PubMed ID: 19557000
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Interplay between the DNA damage proteins MDC1 and ATM in the regulation of the spindle assembly checkpoint.
    Eliezer Y; Argaman L; Kornowski M; Roniger M; Goldberg M
    J Biol Chem; 2014 Mar; 289(12):8182-93. PubMed ID: 24509855
    [TBL] [Abstract][Full Text] [Related]  

  • 28. The direct interaction between 53BP1 and MDC1 is required for the recruitment of 53BP1 to sites of damage.
    Eliezer Y; Argaman L; Rhie A; Doherty AJ; Goldberg M
    J Biol Chem; 2009 Jan; 284(1):426-435. PubMed ID: 18986980
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Regulation of DNA damage following termination of Hedgehog (HH) survival signaling at the level of the GLI genes in human colon cancer.
    Agyeman A; Mazumdar T; Houghton JA
    Oncotarget; 2012 Aug; 3(8):854-68. PubMed ID: 23097684
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Mdb1, a fission yeast homolog of human MDC1, modulates DNA damage response and mitotic spindle function.
    Wei Y; Wang HT; Zhai Y; Russell P; Du LL
    PLoS One; 2014; 9(5):e97028. PubMed ID: 24806815
    [TBL] [Abstract][Full Text] [Related]  

  • 31. MDC1 methylation mediated by lysine methyltransferases EHMT1 and EHMT2 regulates active ATM accumulation flanking DNA damage sites.
    Watanabe S; Iimori M; Chan DV; Hara E; Kitao H; Maehara Y
    Sci Rep; 2018 Jul; 8(1):10888. PubMed ID: 30022091
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Disruption of DNA Damage-Response by Propyl Gallate and 9-Aminoacridine.
    Matsuda S; Matsuda Y; Yanagisawa SY; Ikura M; Ikura T; Matsuda T
    Toxicol Sci; 2016 Jun; 151(2):224-35. PubMed ID: 26928355
    [TBL] [Abstract][Full Text] [Related]  

  • 33. MDC1 collaborates with TopBP1 in DNA replication checkpoint control.
    Wang J; Gong Z; Chen J
    J Cell Biol; 2011 Apr; 193(2):267-73. PubMed ID: 21482717
    [TBL] [Abstract][Full Text] [Related]  

  • 34. MDC1 directs chromosome-wide silencing of the sex chromosomes in male germ cells.
    Ichijima Y; Ichijima M; Lou Z; Nussenzweig A; Camerini-Otero RD; Chen J; Andreassen PR; Namekawa SH
    Genes Dev; 2011 May; 25(9):959-71. PubMed ID: 21536735
    [TBL] [Abstract][Full Text] [Related]  

  • 35. ID3 regulates the MDC1-mediated DNA damage response in order to maintain genome stability.
    Lee JH; Park SJ; Hariharasudhan G; Kim MJ; Jung SM; Jeong SY; Chang IY; Kim C; Kim E; Yu J; Bae S; You HJ
    Nat Commun; 2017 Oct; 8(1):903. PubMed ID: 29026069
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Polo-like kinase 1 inhibits DNA damage response during mitosis.
    Benada J; Burdová K; Lidak T; von Morgen P; Macurek L
    Cell Cycle; 2015; 14(2):219-31. PubMed ID: 25607646
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Effect of silencing of mediator of DNA damage checkpoint protein 1 on the growth of oral squamous cell carcinoma in vitro and in vivo.
    Zhang X; Hu F; Liu L; Xu B
    Eur J Oral Sci; 2019 Dec; 127(6):494-499. PubMed ID: 31786813
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Constitutive phosphorylation of MDC1 physically links the MRE11-RAD50-NBS1 complex to damaged chromatin.
    Spycher C; Miller ES; Townsend K; Pavic L; Morrice NA; Janscak P; Stewart GS; Stucki M
    J Cell Biol; 2008 Apr; 181(2):227-40. PubMed ID: 18411308
    [TBL] [Abstract][Full Text] [Related]  

  • 39. STAT-1 facilitates the ATM activated checkpoint pathway following DNA damage.
    Townsend PA; Cragg MS; Davidson SM; McCormick J; Barry S; Lawrence KM; Knight RA; Hubank M; Chen PL; Latchman DS; Stephanou A
    J Cell Sci; 2005 Apr; 118(Pt 8):1629-39. PubMed ID: 15784679
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Wild-type p53-induced phosphatase 1 dephosphorylates histone variant gamma-H2AX and suppresses DNA double strand break repair.
    Moon SH; Lin L; Zhang X; Nguyen TA; Darlington Y; Waldman AS; Lu X; Donehower LA
    J Biol Chem; 2010 Apr; 285(17):12935-47. PubMed ID: 20118229
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 13.