BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

329 related articles for article (PubMed ID: 32870330)

  • 1. DYRK1A: a down syndrome-related dual protein kinase with a versatile role in tumorigenesis.
    Laham AJ; Saber-Ayad M; El-Awady R
    Cell Mol Life Sci; 2021 Jan; 78(2):603-619. PubMed ID: 32870330
    [TBL] [Abstract][Full Text] [Related]  

  • 2. DYRK1A regulates the recruitment of 53BP1 to the sites of DNA damage in part through interaction with RNF169.
    Menon VR; Ananthapadmanabhan V; Swanson S; Saini S; Sesay F; Yakovlev V; Florens L; DeCaprio JA; Washburn MP; Dozmorov M; Litovchick L
    Cell Cycle; 2019 Mar; 18(5):531-551. PubMed ID: 30773093
    [TBL] [Abstract][Full Text] [Related]  

  • 3. DYRK1A and DYRK3 promote cell survival through phosphorylation and activation of SIRT1.
    Guo X; Williams JG; Schug TT; Li X
    J Biol Chem; 2010 Apr; 285(17):13223-32. PubMed ID: 20167603
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Dyrk1A phosphorylates p53 and inhibits proliferation of embryonic neuronal cells.
    Park J; Oh Y; Yoo L; Jung MS; Song WJ; Lee SH; Seo H; Chung KC
    J Biol Chem; 2010 Oct; 285(41):31895-906. PubMed ID: 20696760
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mechanism of dual specificity kinase activity of DYRK1A.
    Walte A; Rüben K; Birner-Gruenberger R; Preisinger C; Bamberg-Lemper S; Hilz N; Bracher F; Becker W
    FEBS J; 2013 Sep; 280(18):4495-511. PubMed ID: 23809146
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Regulation of RCAN1 protein activity by Dyrk1A protein-mediated phosphorylation.
    Jung MS; Park JH; Ryu YS; Choi SH; Yoon SH; Kwen MY; Oh JY; Song WJ; Chung SH
    J Biol Chem; 2011 Nov; 286(46):40401-12. PubMed ID: 21965663
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Function and regulation of Dyrk1A: towards understanding Down syndrome.
    Park J; Song WJ; Chung KC
    Cell Mol Life Sci; 2009 Oct; 66(20):3235-40. PubMed ID: 19685005
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Normalizing the gene dosage of Dyrk1A in a mouse model of Down syndrome rescues several Alzheimer's disease phenotypes.
    García-Cerro S; Rueda N; Vidal V; Lantigua S; Martínez-Cué C
    Neurobiol Dis; 2017 Oct; 106():76-88. PubMed ID: 28647555
    [TBL] [Abstract][Full Text] [Related]  

  • 9. DYRK1A autophosphorylation on serine residue 520 modulates its kinase activity via 14-3-3 binding.
    Alvarez M; Altafaj X; Aranda S; de la Luna S
    Mol Biol Cell; 2007 Apr; 18(4):1167-78. PubMed ID: 17229891
    [TBL] [Abstract][Full Text] [Related]  

  • 10. p53 downregulates Down syndrome-associated DYRK1A through miR-1246.
    Zhang Y; Liao JM; Zeng SX; Lu H
    EMBO Rep; 2011 Jun; 12(8):811-7. PubMed ID: 21637297
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Neprilysin Is Suppressed by Dual-Specificity Tyrosine-Phosphorylation Regulated Kinase 1A (DYRK1A) in Down-Syndrome-Derived Fibroblasts.
    Kawakubo T; Mori R; Shirotani K; Iwata N; Asai M
    Biol Pharm Bull; 2017; 40(3):327-333. PubMed ID: 28250274
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Transgenic mouse in vivo library of human Down syndrome critical region 1: association between DYRK1A overexpression, brain development abnormalities, and cell cycle protein alteration.
    Branchi I; Bichler Z; Minghetti L; Delabar JM; Malchiodi-Albedi F; Gonzalez MC; Chettouh Z; Nicolini A; Chabert C; Smith DJ; Rubin EM; Migliore-Samour D; Alleva E
    J Neuropathol Exp Neurol; 2004 May; 63(5):429-40. PubMed ID: 15198122
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Dual-specificity tyrosine phosphorylation-regulated kinase 1A does not require tyrosine phosphorylation for activity in vitro.
    Adayev T; Chen-Hwang MC; Murakami N; Lee E; Bolton DC; Hwang YW
    Biochemistry; 2007 Jun; 46(25):7614-24. PubMed ID: 17536841
    [TBL] [Abstract][Full Text] [Related]  

  • 14. DYRK1A is required for maintenance of cancer stemness, contributing to tumorigenic potential in oral/oropharyngeal squamous cell carcinoma.
    Martin CE; Nguyen A; Kang MK; Kim RH; Park NH; Shin KH
    Exp Cell Res; 2021 Aug; 405(1):112656. PubMed ID: 34033760
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The Down syndrome-related protein kinase DYRK1A phosphorylates p27(Kip1) and Cyclin D1 and induces cell cycle exit and neuronal differentiation.
    Soppa U; Schumacher J; Florencio Ortiz V; Pasqualon T; Tejedor FJ; Becker W
    Cell Cycle; 2014; 13(13):2084-100. PubMed ID: 24806449
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The role of overexpressed DYRK1A protein in the early onset of neurofibrillary degeneration in Down syndrome.
    Wegiel J; Dowjat K; Kaczmarski W; Kuchna I; Nowicki K; Frackowiak J; Mazur Kolecka B; Wegiel J; Silverman WP; Reisberg B; Deleon M; Wisniewski T; Gong CX; Liu F; Adayev T; Chen-Hwang MC; Hwang YW
    Acta Neuropathol; 2008 Oct; 116(4):391-407. PubMed ID: 18696092
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Dual-specificity tyrosine(Y)-phosphorylation regulated kinase 1A-mediated phosphorylation of amyloid precursor protein: evidence for a functional link between Down syndrome and Alzheimer's disease.
    Ryoo SR; Cho HJ; Lee HW; Jeong HK; Radnaabazar C; Kim YS; Kim MJ; Son MY; Seo H; Chung SH; Song WJ
    J Neurochem; 2008 Mar; 104(5):1333-44. PubMed ID: 18005339
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The DYRK1A gene, encoded in chromosome 21 Down syndrome critical region, bridges between beta-amyloid production and tau phosphorylation in Alzheimer disease.
    Kimura R; Kamino K; Yamamoto M; Nuripa A; Kida T; Kazui H; Hashimoto R; Tanaka T; Kudo T; Yamagata H; Tabara Y; Miki T; Akatsu H; Kosaka K; Funakoshi E; Nishitomi K; Sakaguchi G; Kato A; Hattori H; Uema T; Takeda M
    Hum Mol Genet; 2007 Jan; 16(1):15-23. PubMed ID: 17135279
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Understanding the Multifaceted Role of Human Down Syndrome Kinase DYRK1A.
    Kay LJ; Smulders-Srinivasan TK; Soundararajan M
    Adv Protein Chem Struct Biol; 2016; 105():127-71. PubMed ID: 27567487
    [TBL] [Abstract][Full Text] [Related]  

  • 20.
    Atas-Ozcan H; Brault V; Duchon A; Herault Y
    Genes (Basel); 2021 Nov; 12(11):. PubMed ID: 34828439
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.