195 related articles for article (PubMed ID: 32873626)
1. G-Protein-Coupled Estrogen Receptor 1 Promotes Gender Disparities in Hepatocellular Carcinoma via Modulation of SIN1 and mTOR Complex 2 Activity.
Feng G; Cai J; Huang Y; Zhu X; Gong B; Yang Z; Yan C; Hu Z; Yang L; Wang Z
Mol Cancer Res; 2020 Dec; 18(12):1863-1875. PubMed ID: 32873626
[TBL] [Abstract][Full Text] [Related]
2. Sin1 promotes proliferation and invasion of prostate cancer cells by modulating mTORC2-AKT and AR signaling cascades.
Huang Y; Feng G; Cai J; Peng Q; Yang Z; Yan C; Yang L; Wang Z
Life Sci; 2020 May; 248():117449. PubMed ID: 32088212
[TBL] [Abstract][Full Text] [Related]
3. Estrogen Activation of G-Protein-Coupled Estrogen Receptor 1 Regulates Phosphoinositide 3-Kinase and mTOR Signaling to Promote Liver Growth in Zebrafish and Proliferation of Human Hepatocytes.
Chaturantabut S; Shwartz A; Evason KJ; Cox AG; Labella K; Schepers AG; Yang S; Acuña M; Houvras Y; Mancio-Silva L; Romano S; Gorelick DA; Cohen DE; Zon LI; Bhatia SN; North TE; Goessling W
Gastroenterology; 2019 May; 156(6):1788-1804.e13. PubMed ID: 30641053
[TBL] [Abstract][Full Text] [Related]
4. A Positive Feedback Loop between Akt and mTORC2 via SIN1 Phosphorylation.
Yang G; Murashige DS; Humphrey SJ; James DE
Cell Rep; 2015 Aug; 12(6):937-43. PubMed ID: 26235620
[TBL] [Abstract][Full Text] [Related]
5. Elevated expression of Erbin destabilizes ERα protein and promotes tumorigenesis in hepatocellular carcinoma.
Wu H; Yao S; Zhang S; Wang JR; Guo PD; Li XM; Gan WJ; Mei L; Gao TM; Li JM
J Hepatol; 2017 Jun; 66(6):1193-1204. PubMed ID: 28192186
[TBL] [Abstract][Full Text] [Related]
6. Sin1 phosphorylation impairs mTORC2 complex integrity and inhibits downstream Akt signalling to suppress tumorigenesis.
Liu P; Gan W; Inuzuka H; Lazorchak AS; Gao D; Arojo O; Liu D; Wan L; Zhai B; Yu Y; Yuan M; Kim BM; Shaik S; Menon S; Gygi SP; Lee TH; Asara JM; Manning BD; Blenis J; Su B; Wei W
Nat Cell Biol; 2013 Nov; 15(11):1340-50. PubMed ID: 24161930
[TBL] [Abstract][Full Text] [Related]
7. Neuroprotection in Parkinsonian-treated mice via estrogen receptor α activation requires G protein-coupled estrogen receptor 1.
Bourque M; Morissette M; Di Paolo T
Neuropharmacology; 2015 Aug; 95():343-52. PubMed ID: 25892506
[TBL] [Abstract][Full Text] [Related]
8. The GPER1/SPOP axis mediates ubiquitination-dependent degradation of ERα to inhibit the growth of breast cancer induced by oestrogen.
Zhang N; Sun P; Xu Y; Li H; Liu H; Wang L; Cao Y; Zhou K; TinghuaiWang
Cancer Lett; 2021 Feb; 498():54-69. PubMed ID: 33069770
[TBL] [Abstract][Full Text] [Related]
9. SIN1, a critical component of the mTOR-Rictor complex, is overexpressed and associated with AKT activation in medullary and aggressive papillary thyroid carcinomas.
Moraitis D; Karanikou M; Liakou C; Dimas K; Tzimas G; Tseleni-Balafouta S; Patsouris E; Rassidakis GZ; Kouvaraki MA
Surgery; 2014 Dec; 156(6):1542-8; discussion 1548-9. PubMed ID: 25456951
[TBL] [Abstract][Full Text] [Related]
10. Low-concentration BPF induced cell biological responses by the ERα and GPER1-mediated signaling pathways in MCF-7 breast cancer cells.
Lei B; Huang Y; Liu Y; Xu J; Sun S; Zhang X; Xu G; Wu M; Yu Y; Feng C
Ecotoxicol Environ Saf; 2018 Dec; 165():144-152. PubMed ID: 30195206
[TBL] [Abstract][Full Text] [Related]
11. PtdIns(3,4,5)P3-Dependent Activation of the mTORC2 Kinase Complex.
Liu P; Gan W; Chin YR; Ogura K; Guo J; Zhang J; Wang B; Blenis J; Cantley LC; Toker A; Su B; Wei W
Cancer Discov; 2015 Nov; 5(11):1194-209. PubMed ID: 26293922
[TBL] [Abstract][Full Text] [Related]
12. G protein-coupled estrogen receptor activates PI3K/AKT/mTOR signaling to suppress ferroptosis via SREBP1/SCD1-mediated lipogenesis.
Chen J; Zhao R; Wang Y; Xiao H; Lin W; Diao M; He S; Mei P; Liao Y
Mol Med; 2024 Feb; 30(1):28. PubMed ID: 38383297
[TBL] [Abstract][Full Text] [Related]
13. SIN1 promotes invasion and metastasis of hepatocellular carcinoma by facilitating epithelial-mesenchymal transition.
Xu J; Li X; Yang H; Chang R; Kong C; Yang L
Cancer; 2013 Jun; 119(12):2247-57. PubMed ID: 23564492
[TBL] [Abstract][Full Text] [Related]
14. Inhibition of mTORC2 Induces Cell-Cycle Arrest and Enhances the Cytotoxicity of Doxorubicin by Suppressing MDR1 Expression in HCC Cells.
Chen BW; Chen W; Liang H; Liu H; Liang C; Zhi X; Hu LQ; Yu XZ; Wei T; Ma T; Xue F; Zheng L; Zhao B; Feng XH; Bai XL; Liang TB
Mol Cancer Ther; 2015 Aug; 14(8):1805-15. PubMed ID: 26026051
[TBL] [Abstract][Full Text] [Related]
15. Sin1 (Stress-Activated Protein Kinase-Interacting Protein) Regulates Ischemia-Induced Microthrombosis Through Integrin αIIbβ3-Mediated Outside-In Signaling and Hypoxia Responses in Platelets.
Xu Y; Ouyang X; Yan L; Zhang M; Hu Z; Gu J; Fan X; Zhang L; Zhang J; Xue S; Chen G; Su B; Liu J
Arterioscler Thromb Vasc Biol; 2018 Dec; 38(12):2793-2805. PubMed ID: 30571167
[TBL] [Abstract][Full Text] [Related]
16. G Protein-Coupled Estrogen Receptor 1 Mediates Acute Estrogen-Induced Cardioprotection via MEK/ERK/GSK-3β Pathway after Ischemia/Reperfusion.
Kabir ME; Singh H; Lu R; Olde B; Leeb-Lundberg LM; Bopassa JC
PLoS One; 2015; 10(9):e0135988. PubMed ID: 26356837
[TBL] [Abstract][Full Text] [Related]
17. Dehydroepiandrosterone Activation of G-protein-coupled Estrogen Receptor Rapidly Stimulates MicroRNA-21 Transcription in Human Hepatocellular Carcinoma Cells.
Teng Y; Radde BN; Litchfield LM; Ivanova MM; Prough RA; Clark BJ; Doll MA; Hein DW; Klinge CM
J Biol Chem; 2015 Jun; 290(25):15799-15811. PubMed ID: 25969534
[TBL] [Abstract][Full Text] [Related]
18. Cystine Induced-mTORC2 Activation through Promoting Sin1 Phosphorylation to Suppress Cancer Cell Ferroptosis.
Wang G; Chen L; Qin S; Zheng Y; Xia C; Yao J; Wang P; Deng L
Mol Nutr Food Res; 2022 Dec; 66(23):e2200186. PubMed ID: 36189894
[TBL] [Abstract][Full Text] [Related]
19. Heat Stress-Induced PI3K/mTORC2-Dependent AKT Signaling Is a Central Mediator of Hepatocellular Carcinoma Survival to Thermal Ablation Induced Heat Stress.
Thompson SM; Callstrom MR; Jondal DE; Butters KA; Knudsen BE; Anderson JL; Lien KR; Sutor SL; Lee JS; Thorgeirsson SS; Grande JP; Roberts LR; Woodrum DA
PLoS One; 2016; 11(9):e0162634. PubMed ID: 27611696
[TBL] [Abstract][Full Text] [Related]
20. Stabilization of MORC2 by estrogen and antiestrogens through GPER1- PRKACA-CMA pathway contributes to estrogen-induced proliferation and endocrine resistance of breast cancer cells.
Yang F; Xie HY; Yang LF; Zhang L; Zhang FL; Liu HY; Li DQ; Shao ZM
Autophagy; 2020 Jun; 16(6):1061-1076. PubMed ID: 32401166
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
