BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

315 related articles for article (PubMed ID: 32873644)

  • 1. B cells expressing authentic naive human VRC01-class BCRs can be recruited to germinal centers and affinity mature in multiple independent mouse models.
    Huang D; Abbott RK; Havenar-Daughton C; Skog PD; Al-Kolla R; Groschel B; Blane TR; Menis S; Tran JT; Thinnes TC; Volpi SA; Liguori A; Schiffner T; Villegas SM; Kalyuzhniy O; Pintea M; Voss JE; Phelps N; Tingle R; Rodriguez AR; Martin G; Kupryianov S; deCamp A; Schief WR; Nemazee D; Crotty S
    Proc Natl Acad Sci U S A; 2020 Sep; 117(37):22920-22931. PubMed ID: 32873644
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The human naive B cell repertoire contains distinct subclasses for a germline-targeting HIV-1 vaccine immunogen.
    Havenar-Daughton C; Sarkar A; Kulp DW; Toy L; Hu X; Deresa I; Kalyuzhniy O; Kaushik K; Upadhyay AA; Menis S; Landais E; Cao L; Diedrich JK; Kumar S; Schiffner T; Reiss SM; Seumois G; Yates JR; Paulson JC; Bosinger SE; Wilson IA; Schief WR; Crotty S
    Sci Transl Med; 2018 Jul; 10(448):. PubMed ID: 29973404
    [TBL] [Abstract][Full Text] [Related]  

  • 3. HIV-1 broadly neutralizing antibody precursor B cells revealed by germline-targeting immunogen.
    Jardine JG; Kulp DW; Havenar-Daughton C; Sarkar A; Briney B; Sok D; Sesterhenn F; Ereño-Orbea J; Kalyuzhniy O; Deresa I; Hu X; Spencer S; Jones M; Georgeson E; Adachi Y; Kubitz M; deCamp AC; Julien JP; Wilson IA; Burton DR; Crotty S; Schief WR
    Science; 2016 Mar; 351(6280):1458-63. PubMed ID: 27013733
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Glycan Masking Focuses Immune Responses to the HIV-1 CD4-Binding Site and Enhances Elicitation of VRC01-Class Precursor Antibodies.
    Duan H; Chen X; Boyington JC; Cheng C; Zhang Y; Jafari AJ; Stephens T; Tsybovsky Y; Kalyuzhniy O; Zhao P; Menis S; Nason MC; Normandin E; Mukhamedova M; DeKosky BJ; Wells L; Schief WR; Tian M; Alt FW; Kwong PD; Mascola JR
    Immunity; 2018 Aug; 49(2):301-311.e5. PubMed ID: 30076101
    [TBL] [Abstract][Full Text] [Related]  

  • 5. HIV-1 VRC01 Germline-Targeting Immunogens Select Distinct Epitope-Specific B Cell Receptors.
    Lin YR; Parks KR; Weidle C; Naidu AS; Khechaduri A; Riker AO; Takushi B; Chun JH; Borst AJ; Veesler D; Stuart A; Agrawal P; Gray M; Pancera M; Huang PS; Stamatatos L
    Immunity; 2020 Oct; 53(4):840-851.e6. PubMed ID: 33053332
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Precursor Frequency and Affinity Determine B Cell Competitive Fitness in Germinal Centers, Tested with Germline-Targeting HIV Vaccine Immunogens.
    Abbott RK; Lee JH; Menis S; Skog P; Rossi M; Ota T; Kulp DW; Bhullar D; Kalyuzhniy O; Havenar-Daughton C; Schief WR; Nemazee D; Crotty S
    Immunity; 2018 Jan; 48(1):133-146.e6. PubMed ID: 29287996
    [TBL] [Abstract][Full Text] [Related]  

  • 7. mRNA-LNP prime boost evolves precursors toward VRC01-like broadly neutralizing antibodies in preclinical humanized mouse models.
    Wang X; Cottrell CA; Hu X; Ray R; Bottermann M; Villavicencio PM; Yan Y; Xie Z; Warner JE; Ellis-Pugh JR; Kalyuzhniy O; Liguori A; Willis JR; Menis S; Rämisch S; Eskandarzadeh S; Kubitz M; Tingle R; Phelps N; Groschel B; Himansu S; Carfi A; Kirsch KH; Weldon SR; Nair U; Schief WR; Batista FD
    Sci Immunol; 2024 May; 9(95):eadn0622. PubMed ID: 38753808
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Priming HIV-1 broadly neutralizing antibody precursors in human Ig loci transgenic mice.
    Sok D; Briney B; Jardine JG; Kulp DW; Menis S; Pauthner M; Wood A; Lee EC; Le KM; Jones M; Ramos A; Kalyuzhniy O; Adachi Y; Kubitz M; MacPherson S; Bradley A; Friedrich GA; Schief WR; Burton DR
    Science; 2016 Sep; 353(6307):1557-1560. PubMed ID: 27608668
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Humanized V(D)J-rearranging and TdT-expressing mouse vaccine models with physiological HIV-1 broadly neutralizing antibody precursors.
    Luo S; Jing C; Ye AY; Kratochvil S; Cottrell CA; Koo JH; Chapdelaine Williams A; Francisco LV; Batra H; Lamperti E; Kalyuzhniy O; Zhang Y; Barbieri A; Manis JP; Haynes BF; Schief WR; Batista FD; Tian M; Alt FW
    Proc Natl Acad Sci U S A; 2023 Jan; 120(1):e2217883120. PubMed ID: 36574685
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Multiplexed CRISPR/CAS9-mediated engineering of pre-clinical mouse models bearing native human B cell receptors.
    Wang X; Ray R; Kratochvil S; Melzi E; Lin YC; Giguere S; Xu L; Warner J; Cheon D; Liguori A; Groschel B; Phelps N; Adachi Y; Tingle R; Wu L; Crotty S; Kirsch KH; Nair U; Schief WR; Batista FD
    EMBO J; 2021 Jan; 40(2):e105926. PubMed ID: 33258500
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Heterologous prime-boost vaccination drives early maturation of HIV broadly neutralizing antibody precursors in humanized mice.
    Cottrell CA; Hu X; Lee JH; Skog P; Luo S; Flynn CT; McKenney KR; Hurtado J; Kalyuzhniy O; Liguori A; Willis JR; Landais E; Raemisch S; Chen X; Baboo S; Himansu S; Diedrich JK; Duan H; Cheng C; Schiffner T; Bader DLV; Kulp DW; Tingle R; Georgeson E; Eskandarzadeh S; Alavi N; Lu D; Sincomb T; Kubitz M; Mullen TM; Yates JR; Paulson JC; Mascola JR; Alt FW; Briney B; Sok D; Schief WR
    Sci Transl Med; 2024 May; 16(748):eadn0223. PubMed ID: 38753806
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Diverse recombinant HIV-1 Envs fail to activate B cells expressing the germline B cell receptors of the broadly neutralizing anti-HIV-1 antibodies PG9 and 447-52D.
    McGuire AT; Glenn JA; Lippy A; Stamatatos L
    J Virol; 2014 Mar; 88(5):2645-57. PubMed ID: 24352455
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Overcoming Steric Restrictions of VRC01 HIV-1 Neutralizing Antibodies through Immunization.
    Parks KR; MacCamy AJ; Trichka J; Gray M; Weidle C; Borst AJ; Khechaduri A; Takushi B; Agrawal P; Guenaga J; Wyatt RT; Coler R; Seaman M; LaBranche C; Montefiori DC; Veesler D; Pancera M; McGuire A; Stamatatos L
    Cell Rep; 2019 Dec; 29(10):3060-3072.e7. PubMed ID: 31801073
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Immunogenicity of RNA Replicons Encoding HIV Env Immunogens Designed for Self-Assembly into Nanoparticles.
    Melo M; Porter E; Zhang Y; Silva M; Li N; Dobosh B; Liguori A; Skog P; Landais E; Menis S; Sok D; Nemazee D; Schief WR; Weiss R; Irvine DJ
    Mol Ther; 2019 Dec; 27(12):2080-2090. PubMed ID: 31515132
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Affinity gaps among B cells in germinal centers drive the selection of MPER precursors.
    Ray R; Schiffner T; Wang X; Yan Y; Rantalainen K; Lee CD; Parikh S; Reyes RA; Dale GA; Lin YC; Pecetta S; Giguere S; Swanson O; Kratochvil S; Melzi E; Phung I; Madungwe L; Kalyuzhniy O; Warner J; Weldon SR; Tingle R; Lamperti E; Kirsch KH; Phelps N; Georgeson E; Adachi Y; Kubitz M; Nair U; Crotty S; Wilson IA; Schief WR; Batista FD
    Nat Immunol; 2024 Jun; 25(6):1083-1096. PubMed ID: 38816616
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Specifically modified Env immunogens activate B-cell precursors of broadly neutralizing HIV-1 antibodies in transgenic mice.
    McGuire AT; Gray MD; Dosenovic P; Gitlin AD; Freund NT; Petersen J; Correnti C; Johnsen W; Kegel R; Stuart AB; Glenn J; Seaman MS; Schief WR; Strong RK; Nussenzweig MC; Stamatatos L
    Nat Commun; 2016 Feb; 7():10618. PubMed ID: 26907590
    [TBL] [Abstract][Full Text] [Related]  

  • 17. HIV-1 envelope glycan modifications that permit neutralization by germline-reverted VRC01-class broadly neutralizing antibodies.
    LaBranche CC; McGuire AT; Gray MD; Behrens S; Kwong PDK; Chen X; Zhou T; Sattentau QJ; Peacock J; Eaton A; Greene K; Gao H; Tang H; Perez LG; Chen X; Saunders KO; Kwong PD; Mascola JR; Haynes BF; Stamatatos L; Montefiori DC
    PLoS Pathog; 2018 Nov; 14(11):e1007431. PubMed ID: 30395637
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Rational HIV immunogen design to target specific germline B cell receptors.
    Jardine J; Julien JP; Menis S; Ota T; Kalyuzhniy O; McGuire A; Sok D; Huang PS; MacPherson S; Jones M; Nieusma T; Mathison J; Baker D; Ward AB; Burton DR; Stamatatos L; Nemazee D; Wilson IA; Schief WR
    Science; 2013 May; 340(6133):711-6. PubMed ID: 23539181
    [TBL] [Abstract][Full Text] [Related]  

  • 19. HIV-1 VACCINES. Priming a broadly neutralizing antibody response to HIV-1 using a germline-targeting immunogen.
    Jardine JG; Ota T; Sok D; Pauthner M; Kulp DW; Kalyuzhniy O; Skog PD; Thinnes TC; Bhullar D; Briney B; Menis S; Jones M; Kubitz M; Spencer S; Adachi Y; Burton DR; Schief WR; Nemazee D
    Science; 2015 Jul; 349(6244):156-61. PubMed ID: 26089355
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Inference of the HIV-1 VRC01 Antibody Lineage Unmutated Common Ancestor Reveals Alternative Pathways to Overcome a Key Glycan Barrier.
    Bonsignori M; Scott E; Wiehe K; Easterhoff D; Alam SM; Hwang KK; Cooper M; Xia SM; Zhang R; Montefiori DC; Henderson R; Nie X; Kelsoe G; Moody MA; Chen X; Joyce MG; Kwong PD; Connors M; Mascola JR; McGuire AT; Stamatatos L; Medina-Ramírez M; Sanders RW; Saunders KO; Kepler TB; Haynes BF
    Immunity; 2018 Dec; 49(6):1162-1174.e8. PubMed ID: 30552024
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.