136 related articles for article (PubMed ID: 32877805)
1. Isoquinolinone derivatives as potent CNS multi-receptor D
Jin J; Zhang K; Dou F; Hao C; Zhang Y; Cao X; Gao L; Xiong J; Liu X; Liu BF; Zhang G; Chen Y
Eur J Med Chem; 2020 Dec; 207():112709. PubMed ID: 32877805
[TBL] [Abstract][Full Text] [Related]
2. Conformationally constrained butyrophenones with mixed dopaminergic (D(2)) and serotoninergic (5-HT(2A), 5-HT(2C)) affinities: synthesis, pharmacology, 3D-QSAR, and molecular modeling of (aminoalkyl)benzo- and -thienocycloalkanones as putative atypical antipsychotics.
Raviña E; Negreira J; Cid J; Masaguer CF; Rosa E; Rivas ME; Fontenla JA; Loza MI; Tristán H; Cadavid MI; Sanz F; Lozoya E; Carotti A; Carrieri A
J Med Chem; 1999 Jul; 42(15):2774-97. PubMed ID: 10425088
[TBL] [Abstract][Full Text] [Related]
3. In Vitro and In Vivo Characterization of PCC0104005, a Novel Modulator of Serotonin-Dopamine Activity, as an Atypical Antipsychotic Drug.
Xu Y; Zhu X; Wang H; Sun S; Yue X; Tian J
Sci Rep; 2018 May; 8(1):6892. PubMed ID: 29720711
[TBL] [Abstract][Full Text] [Related]
4. Synthesis and Pharmacology of the enantiomers of the potential atypical antipsychotic agents 5-OMe-BPAT and 5-OMe-(2,6-di-OMe)-BPAT.
Homan EJ; Copinga S; Unelius L; Jackson DM; Wikström HV; Grol CJ
Bioorg Med Chem; 1999 Jul; 7(7):1263-71. PubMed ID: 10465402
[TBL] [Abstract][Full Text] [Related]
5. Synthesis and biological investigation of coumarin piperazine (piperidine) derivatives as potential multireceptor atypical antipsychotics.
Chen Y; Wang S; Xu X; Liu X; Yu M; Zhao S; Liu S; Qiu Y; Zhang T; Liu BF; Zhang G
J Med Chem; 2013 Jun; 56(11):4671-90. PubMed ID: 23675993
[TBL] [Abstract][Full Text] [Related]
6. Synthesis and pharmacological evaluation of piperidine (piperazine)-amide substituted derivatives as multi-target antipsychotics.
Huang L; Gao L; Zhang X; Yin L; Hu J; Song T; Chen Y
Bioorg Med Chem Lett; 2020 Oct; 30(20):127506. PubMed ID: 32828898
[TBL] [Abstract][Full Text] [Related]
7. Discovery of a new class of multi-target heterocycle piperidine derivatives as potential antipsychotics with pro-cognitive effect.
Gao L; Hao C; Chen J; Ma R; Zheng L; Wu Q; Liu X; Liu BF; Zhang G; Chen Y; Jin J
Bioorg Med Chem Lett; 2021 May; 40():127909. PubMed ID: 33705900
[TBL] [Abstract][Full Text] [Related]
8. Design, Synthesis and Biological Investigation of Flavone Derivatives as Potential Multi-Receptor Atypical Antipsychotics.
Gao L; Yang Z; Xiong J; Hao C; Ma R; Liu X; Liu BF; Jin J; Zhang G; Chen Y
Molecules; 2020 Sep; 25(18):. PubMed ID: 32911828
[TBL] [Abstract][Full Text] [Related]
9. Orally active benzamide antipsychotic agents with affinity for dopamine D2, serotonin 5-HT1A, and adrenergic alpha1 receptors.
Reitz AB; Baxter EW; Codd EE; Davis CB; Jordan AD; Maryanoff BE; Maryanoff CA; McDonnell ME; Powell ET; Renzi MJ; Schott MR; Scott MK; Shank RP; Vaught JL
J Med Chem; 1998 Jun; 41(12):1997-2009. PubMed ID: 9622541
[TBL] [Abstract][Full Text] [Related]
10. Synthesis and Biological Evaluation of Fused Tricyclic Heterocycle Piperazine (Piperidine) Derivatives As Potential Multireceptor Atypical Antipsychotics.
Cao X; Zhang Y; Chen Y; Qiu Y; Yu M; Xu X; Liu X; Liu BF; Zhang L; Zhang G
J Med Chem; 2018 Nov; 61(22):10017-10039. PubMed ID: 30383372
[TBL] [Abstract][Full Text] [Related]
11. Brexpiprazole I: in vitro and in vivo characterization of a novel serotonin-dopamine activity modulator.
Maeda K; Sugino H; Akazawa H; Amada N; Shimada J; Futamura T; Yamashita H; Ito N; McQuade RD; Mørk A; Pehrson AL; Hentzer M; Nielsen V; Bundgaard C; Arnt J; Stensbøl TB; Kikuchi T
J Pharmacol Exp Ther; 2014 Sep; 350(3):589-604. PubMed ID: 24947465
[TBL] [Abstract][Full Text] [Related]
12. Synthesis and biological investigation of tetrahydropyridopyrimidinone derivatives as potential multireceptor atypical antipsychotics.
Xiamuxi H; Wang Z; Li J; Wang Y; Wu C; Yang F; Jiang X; Liu Y; Zhao Q; Chen W; Zhang J; Xie Y; Hu T; Xu M; Guo S; Akber Aisa H; He Y; Shen J
Bioorg Med Chem; 2017 Sep; 25(17):4904-4916. PubMed ID: 28774576
[TBL] [Abstract][Full Text] [Related]
13. New arylpiperazinylalkyl derivatives of 8-alkoxy-purine-2,6-dione and dihydro[1,3]oxazolo[2,3-f]purinedione targeting the serotonin 5-HT1A /5-HT2A /5-HT7 and dopamine D2 receptors.
Chłoń-Rzepa G; Zagórska A; Bucki A; Kołaczkowski M; Pawłowski M; Satała G; Bojarski AJ; Partyka A; Wesołowska A; Pękala E; Słoczyńska K
Arch Pharm (Weinheim); 2015 Apr; 348(4):242-53. PubMed ID: 25773907
[TBL] [Abstract][Full Text] [Related]
14. Novel benzothiazolin-2-one and benzoxazin-3-one arylpiperazine derivatives with mixed 5HT1A/D2 affinity as potential atypical antipsychotics.
Taverne T; Diouf O; Depreux P; Poupaert JH; Lesieur D; Guardiola-Lemaître B; Renard P; Rettori MC; Caignard DH; Pfeiffer B
J Med Chem; 1998 Jun; 41(12):2010-8. PubMed ID: 9622542
[TBL] [Abstract][Full Text] [Related]
15. Synthesis and biological evaluation of a series of multi-target N-substituted cyclic imide derivatives with potential antipsychotic effect.
Xu M; Wang Y; Yang F; Wu C; Wang Z; Ye B; Jiang X; Zhao Q; Li J; Liu Y; Zhang J; Tian G; He Y; Shen J; Jiang H
Eur J Med Chem; 2018 Feb; 145():74-85. PubMed ID: 29324345
[TBL] [Abstract][Full Text] [Related]
16. Continuation of structure-activity relationship study of novel benzamide derivatives as potential antipsychotics.
Xu M; Guo S; Yang F; Wang Y; Wu C; Jiang X; Zhao Q; Chen W; Tian G; Zhu F; Xie Y; Hu T; Wang Z; He Y; Shen J
Arch Pharm (Weinheim); 2019 Apr; 352(4):e1800306. PubMed ID: 30702760
[TBL] [Abstract][Full Text] [Related]
17. The impact of the halogen bonding on D
Partyka A; Kurczab R; Canale V; Satała G; Marciniec K; Pasierb A; Jastrzębska-Więsek M; Pawłowski M; Wesołowska A; Bojarski AJ; Zajdel P
Bioorg Med Chem; 2017 Jul; 25(14):3638-3648. PubMed ID: 28529043
[TBL] [Abstract][Full Text] [Related]
18. Quinoline- and isoquinoline-sulfonamide derivatives of LCAP as potent CNS multi-receptor-5-HT1A/5-HT2A/5-HT7 and D2/D3/D4-agents: the synthesis and pharmacological evaluation.
Zajdel P; Marciniec K; Maślankiewicz A; Satała G; Duszyńska B; Bojarski AJ; Partyka A; Jastrzębska-Więsek M; Wróbel D; Wesołowska A; Pawłowski M
Bioorg Med Chem; 2012 Feb; 20(4):1545-56. PubMed ID: 22277589
[TBL] [Abstract][Full Text] [Related]
19. Synthesis and pharmacological evaluation of piperidine (piperazine)-substituted benzoxazole derivatives as multi-target antipsychotics.
Huang L; Zhang W; Zhang X; Yin L; Chen B; Song J
Bioorg Med Chem Lett; 2015 Nov; 25(22):5299-305. PubMed ID: 26483200
[TBL] [Abstract][Full Text] [Related]
20. Novel 4-alkyl-1-arylpiperazines and 1,2,3,4-tetrahydroisoquinolines containing diphenylmethylamino or diphenylmethoxy fragment with differentiated 5-HT1A/5-HT2A/D2 receptor activity.
Paluchowska MH; Mokrosz MJ; Charakchieva-Minol S; Duszyńska B; Kozioł A; Wesołowska A; Stachowicz K; Chojnacka-Wójcik E
Pol J Pharmacol; 2003; 55(4):543-52. PubMed ID: 14581712
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
