These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

220 related articles for article (PubMed ID: 32886496)

  • 1. Small-Molecule Activity-Based Probe for Monitoring Ubiquitin C-Terminal Hydrolase L1 (UCHL1) Activity in Live Cells and Zebrafish Embryos.
    Kooij R; Liu S; Sapmaz A; Xin BT; Janssen GMC; van Veelen PA; Ovaa H; Dijke PT; Geurink PP
    J Am Chem Soc; 2020 Sep; 142(39):16825-16841. PubMed ID: 32886496
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Ubiquitin C-Terminal Hydrolase L1 regulates autophagy by inhibiting autophagosome formation through its deubiquitinating enzyme activity.
    Yan C; Huo H; Yang C; Zhang T; Chu Y; Liu Y
    Biochem Biophys Res Commun; 2018 Mar; 497(2):726-733. PubMed ID: 29462615
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Discovery of a Potent and Selective Covalent Inhibitor and Activity-Based Probe for the Deubiquitylating Enzyme UCHL1, with Antifibrotic Activity.
    Panyain N; Godinat A; Lanyon-Hogg T; Lachiondo-Ortega S; Will EJ; Soudy C; Mondal M; Mason K; Elkhalifa S; Smith LM; Harrigan JA; Tate EW
    J Am Chem Soc; 2020 Jul; 142(28):12020-12026. PubMed ID: 32579346
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Optimization and Anti-Cancer Properties of Fluoromethylketones as Covalent Inhibitors for Ubiquitin C-Terminal Hydrolase L1.
    Krabill AD; Chen H; Hussain S; Hewitt CS; Imhoff RD; Muli CS; Das C; Galardy PJ; Wendt MK; Flaherty DP
    Molecules; 2021 Feb; 26(5):. PubMed ID: 33668938
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Deubiquitinase Activity Profiling Identifies UCHL1 as a Candidate Oncoprotein That Promotes TGFβ-Induced Breast Cancer Metastasis.
    Liu S; González-Prieto R; Zhang M; Geurink PP; Kooij R; Iyengar PV; van Dinther M; Bos E; Zhang X; Le Dévédec SE; van de Water B; Koning RI; Zhu HJ; Mesker WE; Vertegaal ACO; Ovaa H; Zhang L; Martens JWM; Ten Dijke P
    Clin Cancer Res; 2020 Mar; 26(6):1460-1473. PubMed ID: 31857432
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Development of Ubiquitin Variants with Selectivity for Ubiquitin C-Terminal Hydrolase Deubiquitinases.
    Hewitt CS; Krabill AD; Das C; Flaherty DP
    Biochemistry; 2020 Sep; 59(37):3447-3462. PubMed ID: 32865982
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The co-crystal structure of ubiquitin carboxy-terminal hydrolase L1 (UCHL1) with a tripeptide fluoromethyl ketone (Z-VAE(OMe)-FMK).
    Davies CW; Chaney J; Korbel G; Ringe D; Petsko GA; Ploegh H; Das C
    Bioorg Med Chem Lett; 2012 Jun; 22(12):3900-4. PubMed ID: 22617491
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Ubiquitin C-Terminal Hydrolase L1: Biochemical and Cellular Characterization of a Covalent Cyanopyrrolidine-Based Inhibitor.
    Krabill AD; Chen H; Hussain S; Feng C; Abdullah A; Das C; Aryal UK; Post CB; Wendt MK; Galardy PJ; Flaherty DP
    Chembiochem; 2020 Mar; 21(5):712-722. PubMed ID: 31449350
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Control of BACE1 degradation and APP processing by ubiquitin carboxyl-terminal hydrolase L1.
    Zhang M; Deng Y; Luo Y; Zhang S; Zou H; Cai F; Wada K; Song W
    J Neurochem; 2012 Mar; 120(6):1129-38. PubMed ID: 22212137
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Ubiquitin carboxyl-terminal hydrolase L1, a novel deubiquitinating enzyme in the vasculature, attenuates NF-kappaB activation.
    Takami Y; Nakagami H; Morishita R; Katsuya T; Cui TX; Ichikawa T; Saito Y; Hayashi H; Kikuchi Y; Nishikawa T; Baba Y; Yasuda O; Rakugi H; Ogihara T; Kaneda Y
    Arterioscler Thromb Vasc Biol; 2007 Oct; 27(10):2184-90. PubMed ID: 17690318
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Ubiquitin Carboxyl-Terminal Hydrolase L1 and Its Role in Parkinson's Disease.
    Buneeva O; Medvedev A
    Int J Mol Sci; 2024 Jan; 25(2):. PubMed ID: 38279302
    [TBL] [Abstract][Full Text] [Related]  

  • 12. MicroRNA-922 promotes tau phosphorylation by downregulating ubiquitin carboxy-terminal hydrolase L1 (UCHL1) expression in the pathogenesis of Alzheimer's disease.
    Zhao ZB; Wu L; Xiong R; Wang LL; Zhang B; Wang C; Li H; Liang L; Chen SD
    Neuroscience; 2014 Sep; 275():232-7. PubMed ID: 24950120
    [TBL] [Abstract][Full Text] [Related]  

  • 13. UCHL1 as a novel target in breast cancer: emerging insights from cell and chemical biology.
    Mondal M; Conole D; Nautiyal J; Tate EW
    Br J Cancer; 2022 Jan; 126(1):24-33. PubMed ID: 34497382
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Ubiquitin carboxy-terminal hydrolase L1 - physiology and pathology.
    Matuszczak E; Tylicka M; Komarowska MD; Debek W; Hermanowicz A
    Cell Biochem Funct; 2020 Jul; 38(5):533-540. PubMed ID: 32207552
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Cloning and expression analysis of a Parkinson's disease gene, uch-L1, and its promoter in zebrafish.
    Son OL; Kim HT; Ji MH; Yoo KW; Rhee M; Kim CH
    Biochem Biophys Res Commun; 2003 Dec; 312(3):601-7. PubMed ID: 14680807
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Role of ubiquitin C-terminal hydrolase-L1 in antipolyspermy defense of mammalian oocytes.
    Susor A; Liskova L; Toralova T; Pavlok A; Pivonkova K; Karabinova P; Lopatarova M; Sutovsky P; Kubelka M
    Biol Reprod; 2010 Jun; 82(6):1151-61. PubMed ID: 20164442
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Life and death in the trash heap: The ubiquitin proteasome pathway and UCHL1 in brain aging, neurodegenerative disease and cerebral Ischemia.
    Graham SH; Liu H
    Ageing Res Rev; 2017 Mar; 34():30-38. PubMed ID: 27702698
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Overexpression of ubiquitin carboxyl-terminal hydrolase L1 (UCHL1) delays Alzheimer's progression in vivo.
    Zhang M; Cai F; Zhang S; Zhang S; Song W
    Sci Rep; 2014 Dec; 4():7298. PubMed ID: 25466238
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Systemic treatment with ubiquitin carboxy terminal hydrolase L1 TAT protein ameliorates axonal injury and reduces functional deficits after traumatic brain injury in mice.
    Mi Z; Ma J; Zeh DJ; Rose ME; Henchir JJ; Liu H; Ma X; Cao G; Dixon CE; Graham SH
    Exp Neurol; 2024 Mar; 373():114650. PubMed ID: 38092186
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Increased levels of UCHL1 are a compensatory response to disrupted ubiquitin homeostasis in spinal muscular atrophy and do not represent a viable therapeutic target.
    Powis RA; Mutsaers CA; Wishart TM; Hunter G; Wirth B; Gillingwater TH
    Neuropathol Appl Neurobiol; 2014 Dec; 40(7):873-87. PubMed ID: 25041530
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.