BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

155 related articles for article (PubMed ID: 32888960)

  • 1. The Introduction of a New Flexible In Vivo Predictive Dissolution Apparatus, GIS-Alpha (GIS-α), to Study Dissolution Profiles of BCS Class IIb Drugs, Dipyridamole and Ketoconazole.
    Tsume Y; Patel S; Wang M; Hermans A; Kesisoglou F
    J Pharm Sci; 2020 Nov; 109(11):3471-3479. PubMed ID: 32888960
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The impact of supersaturation level for oral absorption of BCS class IIb drugs, dipyridamole and ketoconazole, using in vivo predictive dissolution system: Gastrointestinal Simulator (GIS).
    Tsume Y; Matsui K; Searls AL; Takeuchi S; Amidon GE; Sun D; Amidon GL
    Eur J Pharm Sci; 2017 May; 102():126-139. PubMed ID: 28263914
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The Combination of GIS and Biphasic to Better Predict In Vivo Dissolution of BCS Class IIb Drugs, Ketoconazole and Raloxifene.
    Tsume Y; Igawa N; Drelich AJ; Amidon GE; Amidon GL
    J Pharm Sci; 2018 Jan; 107(1):307-316. PubMed ID: 28919384
    [TBL] [Abstract][Full Text] [Related]  

  • 4. In Vitro Dissolution of Fluconazole and Dipyridamole in Gastrointestinal Simulator (GIS), Predicting in Vivo Dissolution and Drug-Drug Interaction Caused by Acid-Reducing Agents.
    Matsui K; Tsume Y; Amidon GE; Amidon GL
    Mol Pharm; 2015 Jul; 12(7):2418-28. PubMed ID: 25985298
    [TBL] [Abstract][Full Text] [Related]  

  • 5. In vitro dissolution methodology, mini-Gastrointestinal Simulator (mGIS), predicts better in vivo dissolution of a weak base drug, dasatinib.
    Tsume Y; Takeuchi S; Matsui K; Amidon GE; Amidon GL
    Eur J Pharm Sci; 2015 Aug; 76():203-12. PubMed ID: 25978875
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Utilization of Gastrointestinal Simulator, an in Vivo Predictive Dissolution Methodology, Coupled with Computational Approach To Forecast Oral Absorption of Dipyridamole.
    Matsui K; Tsume Y; Takeuchi S; Searls A; Amidon GL
    Mol Pharm; 2017 Apr; 14(4):1181-1189. PubMed ID: 28231003
    [TBL] [Abstract][Full Text] [Related]  

  • 7. pH-dependent dissolution in vitro and absorption in vivo of weakly basic drugs: development of a canine model.
    Zhou R; Moench P; Heran C; Lu X; Mathias N; Faria TN; Wall DA; Hussain MA; Smith RL; Sun D
    Pharm Res; 2005 Feb; 22(2):188-92. PubMed ID: 15783065
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Improving Dissolution Behavior and Oral Absorption of Drugs with pH-Dependent Solubility Using pH Modifiers: A Physiologically Realistic Mass Transport Analysis.
    Salehi N; Kuminek G; Al-Gousous J; Sperry DC; Greenwood DE; Waltz NM; Amidon GL; Ziff RM; Amidon GE
    Mol Pharm; 2021 Sep; 18(9):3326-3341. PubMed ID: 34428047
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Integration of Precipitation Kinetics From an In Vitro, Multicompartment Transfer System and Mechanistic Oral Absorption Modeling for Pharmacokinetic Prediction of Weakly Basic Drugs.
    Patel S; Zhu W; Xia B; Sharma N; Hermans A; Ehrick JD; Kesisoglou F; Pennington J
    J Pharm Sci; 2019 Jan; 108(1):574-583. PubMed ID: 30395833
    [TBL] [Abstract][Full Text] [Related]  

  • 10. In vitro-in vivo correlation of the effect of supersaturation on the intestinal absorption of BCS Class 2 drugs.
    Higashino H; Hasegawa T; Yamamoto M; Matsui R; Masaoka Y; Kataoka M; Sakuma S; Yamashita S
    Mol Pharm; 2014 Mar; 11(3):746-54. PubMed ID: 24460473
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Revisiting Supersaturation of a Biopharmaceutical Classification System IIB Drug: Evaluation via a Multi-Cup Dissolution Approach and Molecular Dynamic Simulation.
    Gan Y; Xu Y; Zhang X; Hu H; Xiao W; Yu Z; Sun T; Zhang J; Wen C; Zheng S
    Molecules; 2023 Oct; 28(19):. PubMed ID: 37836805
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Predicting in vivo absorption behavior of oral modified release dosage forms containing pH-dependent poorly soluble drugs using a novel pH-adjusted biphasic in vitro dissolution test.
    Heigoldt U; Sommer F; Daniels R; Wagner KG
    Eur J Pharm Biopharm; 2010 Sep; 76(1):105-11. PubMed ID: 20472059
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Effects of gastric pH on oral drug absorption: In vitro assessment using a dissolution/permeation system reflecting the gastric dissolution process.
    Kataoka M; Fukahori M; Ikemura A; Kubota A; Higashino H; Sakuma S; Yamashita S
    Eur J Pharm Biopharm; 2016 Apr; 101():103-11. PubMed ID: 26873006
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Use of Gastrointestinal Simulator, Mass Transport Analysis, and Absorption Simulation to Investigate the Impact of pH Modifiers in Mitigating Weakly Basic Drugs' Performance Issues Related to Gastric pH: Palbociclib Case Study.
    Kuminek G; Salehi N; Waltz NM; Sperry DC; Greenwood DE; Hate SS; Amidon GE
    Mol Pharm; 2023 Jan; 20(1):147-158. PubMed ID: 36367432
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The effects of degree and duration of supersaturation on in vivo absorption profiles for highly permeable drugs, dipyridamole and ketoconazole.
    Higashino H; Minami K; Takagi T; Kataoka M; Yamashita S
    Eur J Pharm Biopharm; 2023 Aug; 189():48-55. PubMed ID: 37301301
    [TBL] [Abstract][Full Text] [Related]  

  • 16. In vitro dissolution absorption system (IDAS2): Use for the prediction of food viscosity effects on drug dissolution and absorption from oral solid dosage forms.
    Silchenko S; Nessah N; Li J; Li LB; Huang Y; Owen AJ; Hidalgo IJ
    Eur J Pharm Sci; 2020 Feb; 143():105164. PubMed ID: 31760121
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Understanding In Vivo Dissolution of Immediate Release (IR) Solid Oral Drug Products Containing Weak Acid BCS Class 2 (BCS Class 2a) Drugs.
    Li M; Zhang X; Wu D; Anand O; Chen H; Raines K; Yu L
    AAPS J; 2021 Oct; 23(6):113. PubMed ID: 34704158
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Evaluation of various dissolution media for predicting in vivo performance of class I and II drugs.
    Galia E; Nicolaides E; Hörter D; Löbenberg R; Reppas C; Dressman JB
    Pharm Res; 1998 May; 15(5):698-705. PubMed ID: 9619777
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The Evaluation of In Vitro Drug Dissolution of Commercially Available Oral Dosage Forms for Itraconazole in Gastrointestinal Simulator With Biorelevant Media.
    Matsui K; Tsume Y; Amidon GE; Amidon GL
    J Pharm Sci; 2016 Sep; 105(9):2804-2814. PubMed ID: 27020985
    [TBL] [Abstract][Full Text] [Related]  

  • 20. In silico predictions of gastrointestinal drug absorption in pharmaceutical product development: application of the mechanistic absorption model GI-Sim.
    Sjögren E; Westergren J; Grant I; Hanisch G; Lindfors L; Lennernäs H; Abrahamsson B; Tannergren C
    Eur J Pharm Sci; 2013 Jul; 49(4):679-98. PubMed ID: 23727464
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.