111 related articles for article (PubMed ID: 32892640)
1.
Quah SY; Tan MS; Ho KL; Manan NA; Gorfe AA; Deb PK; Sagineedu SR; Stanslas J
Future Med Chem; 2020 Sep; 12(18):1611-1631. PubMed ID: 32892640
[No Abstract] [Full Text] [Related]
2. Andrographolide derivatives inhibit guanine nucleotide exchange and abrogate oncogenic Ras function.
Hocker HJ; Cho KJ; Chen CY; Rambahal N; Sagineedu SR; Shaari K; Stanslas J; Hancock JF; Gorfe AA
Proc Natl Acad Sci U S A; 2013 Jun; 110(25):10201-6. PubMed ID: 23737504
[TBL] [Abstract][Full Text] [Related]
3. Microarray-based identification of differentially expressed genes associated with andrographolide derivatives-induced resistance in colon and prostate cancer cell lines.
Quah SY; Wong CC; Wong HC; Ho KL; Abdul Manan N; Deb PK; Sagineedu SR; Stanslas J
Toxicol Appl Pharmacol; 2021 Aug; 425():115605. PubMed ID: 34087331
[TBL] [Abstract][Full Text] [Related]
4. Molecular Basis for Allosteric Inhibition of GTP-Bound H-Ras Protein by a Small-Molecule Compound Carrying a Naphthalene Ring.
Matsumoto S; Hiraga T; Hayashi Y; Yoshikawa Y; Tsuda C; Araki M; Neya M; Shima F; Kataoka T
Biochemistry; 2018 Sep; 57(36):5350-5358. PubMed ID: 30141910
[TBL] [Abstract][Full Text] [Related]
5. Design, synthesis, and biological evaluation of novel substituted thiourea derivatives as potential anticancer agents for NSCLC by blocking K-Ras protein-effectors interactions.
Zhang Y; Meng X; Tang H; Cheng M; Yang F; Xu W
J Enzyme Inhib Med Chem; 2020 Dec; 35(1):344-353. PubMed ID: 31851852
[TBL] [Abstract][Full Text] [Related]
6. SRJ23, a new semisynthetic andrographolide derivative: in vitro growth inhibition and mechanisms of cell cycle arrest and apoptosis in prostate cancer cells.
Wong HC; Wong CC; Sagineedu SR; Loke SC; Lajis NH; Stanslas J
Cell Biol Toxicol; 2014 Oct; 30(5):269-88. PubMed ID: 25070834
[TBL] [Abstract][Full Text] [Related]
7. 5-Arylidene(chromenyl-methylene)-thiazolidinediones: Potential New Agents against Mutant Oncoproteins K-Ras, N-Ras and B-Raf in Colorectal Cancer and Melanoma.
Nastasă C; Tamaian R; Oniga O; Tiperciuc B
Medicina (Kaunas); 2019 Mar; 55(4):. PubMed ID: 30935124
[No Abstract] [Full Text] [Related]
8. K-Ras
Feng H; Zhang Y; Bos PH; Chambers JM; Dupont MM; Stockwell BR
Biochemistry; 2019 May; 58(21):2542-2554. PubMed ID: 31042025
[TBL] [Abstract][Full Text] [Related]
9. Identification and characterization of new potent inhibitors of dengue virus NS5 proteinase from Andrographis paniculata supercritical extracts on in animal cell culture and in silico approaches.
Kaushik S; Dar L; Kaushik S; Yadav JP
J Ethnopharmacol; 2021 Mar; 267():113541. PubMed ID: 33152438
[TBL] [Abstract][Full Text] [Related]
10. Exploring the Lapse in Druggability: Sequence Analysis, Structural Dynamics and Binding Site Characterization of K-RasG12C Variant, a Feasible Oncotherapeutics Target.
Adeniji EA; Olotu FA; Soliman MES
Anticancer Agents Med Chem; 2018; 18(11):1540-1550. PubMed ID: 30019652
[TBL] [Abstract][Full Text] [Related]
11. GTP Binding and Oncogenic Mutations May Attenuate Hypervariable Region (HVR)-Catalytic Domain Interactions in Small GTPase K-Ras4B, Exposing the Effector Binding Site.
Lu S; Banerjee A; Jang H; Zhang J; Gaponenko V; Nussinov R
J Biol Chem; 2015 Nov; 290(48):28887-900. PubMed ID: 26453300
[TBL] [Abstract][Full Text] [Related]
12. Ras oncoprotein inhibitors: the discovery of potent, ras nucleotide exchange inhibitors and the structural determination of a drug-protein complex.
Taveras AG; Remiszewski SW; Doll RJ; Cesarz D; Huang EC; Kirschmeier P; Pramanik BN; Snow ME; Wang YS; del Rosario JD; Vibulbhan B; Bauer BB; Brown JE; Carr D; Catino J; Evans CA; Girijavallabhan V; Heimark L; James L; Liberles S; Nash C; Perkins L; Senior MM; Tsarbopoulos A; Webber SE
Bioorg Med Chem; 1997 Jan; 5(1):125-33. PubMed ID: 9043664
[TBL] [Abstract][Full Text] [Related]
13. NMR
Sharma AK; Lee SJ; Rigby AC; Townson SA
Biomol NMR Assign; 2018 Oct; 12(2):269-272. PubMed ID: 29721757
[TBL] [Abstract][Full Text] [Related]
14. Nucleotide binding and GTP hydrolysis by the 21-kDa product of the c-H-ras gene as monitored by proton-NMR spectroscopy.
Löw A; Sprinzl M; Limmer S
Eur J Biochem; 1993 Apr; 213(2):781-8. PubMed ID: 8386636
[TBL] [Abstract][Full Text] [Related]
15. K-Ras G-domain binding with signaling lipid phosphatidylinositol (4,5)-phosphate (PIP2): membrane association, protein orientation, and function.
Cao S; Chung S; Kim S; Li Z; Manor D; Buck M
J Biol Chem; 2019 Apr; 294(17):7068-7084. PubMed ID: 30792310
[TBL] [Abstract][Full Text] [Related]
16. Spectroscopic and quantum/classical mechanics based computational studies to compare the ability of Andrographolide and its derivative to inhibit Nitric Oxide Synthase.
A S BG; Prasana JC; Muthu S; Abraham CS; David HA
Spectrochim Acta A Mol Biomol Spectrosc; 2019 Jul; 218():374-387. PubMed ID: 31030004
[TBL] [Abstract][Full Text] [Related]
17. Structural insight into the rearrangement of the switch I region in GTP-bound G12A K-Ras.
Xu S; Long BN; Boris GH; Chen A; Ni S; Kennedy MA
Acta Crystallogr D Struct Biol; 2017 Dec; 73(Pt 12):970-984. PubMed ID: 29199977
[TBL] [Abstract][Full Text] [Related]
18. Oncogenic G12D mutation alters local conformations and dynamics of K-Ras.
Vatansever S; Erman B; Gümüş ZH
Sci Rep; 2019 Aug; 9(1):11730. PubMed ID: 31409810
[TBL] [Abstract][Full Text] [Related]
19. K-Ras Populates Conformational States Differently from Its Isoform H-Ras and Oncogenic Mutant K-RasG12D.
Parker JA; Volmar AY; Pavlopoulos S; Mattos C
Structure; 2018 Jun; 26(6):810-820.e4. PubMed ID: 29706533
[TBL] [Abstract][Full Text] [Related]
20. Multi-target, ensemble-based virtual screening yields novel allosteric KRAS inhibitors at high success rate.
Gupta AK; Wang X; Pagba CV; Prakash P; Sarkar-Banerjee S; Putkey J; Gorfe AA
Chem Biol Drug Des; 2019 Aug; 94(2):1441-1456. PubMed ID: 30903639
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]