BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

317 related articles for article (PubMed ID: 32899451)

  • 1. The Role of Epac in Cancer Progression.
    Wehbe N; Slika H; Mesmar J; Nasser SA; Pintus G; Baydoun S; Badran A; Kobeissy F; Eid AH; Baydoun E
    Int J Mol Sci; 2020 Sep; 21(18):. PubMed ID: 32899451
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Cyclic adenosine 5'-monophosphate-stimulated neurotensin secretion is mediated through Rap1 downstream of both Epac and protein kinase A signaling pathways.
    Li J; O'Connor KL; Cheng X; Mei FC; Uchida T; Townsend CM; Evers BM
    Mol Endocrinol; 2007 Jan; 21(1):159-71. PubMed ID: 17068197
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Cyclic AMP induces integrin-mediated cell adhesion through Epac and Rap1 upon stimulation of the beta 2-adrenergic receptor.
    Rangarajan S; Enserink JM; Kuiperij HB; de Rooij J; Price LS; Schwede F; Bos JL
    J Cell Biol; 2003 Feb; 160(4):487-93. PubMed ID: 12578910
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Cyclic adenosine 3'-5'-monophosphate (cAMP) exerts proliferative and anti-proliferative effects in pituitary cells of different types by activating both cAMP-dependent protein kinase A (PKA) and exchange proteins directly activated by cAMP (Epac).
    Vitali E; Peverelli E; Giardino E; Locatelli M; Lasio GB; Beck-Peccoz P; Spada A; Lania AG; Mantovani G
    Mol Cell Endocrinol; 2014 Mar; 383(1-2):193-202. PubMed ID: 24373949
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Epac, in synergy with cAMP-dependent protein kinase (PKA), is required for cAMP-mediated mitogenesis.
    Hochbaum D; Hong K; Barila G; Ribeiro-Neto F; Altschuler DL
    J Biol Chem; 2008 Feb; 283(8):4464-8. PubMed ID: 18063584
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Differential signaling of cyclic AMP: opposing effects of exchange protein directly activated by cyclic AMP and cAMP-dependent protein kinase on protein kinase B activation.
    Mei FC; Qiao J; Tsygankova OM; Meinkoth JL; Quilliam LA; Cheng X
    J Biol Chem; 2002 Mar; 277(13):11497-504. PubMed ID: 11801596
    [TBL] [Abstract][Full Text] [Related]  

  • 7. EPAC activation inhibits acetaldehyde-induced activation and proliferation of hepatic stellate cell via Rap1.
    Yang Y; Yang F; Wu X; Lv X; Li J
    Can J Physiol Pharmacol; 2016 May; 94(5):498-507. PubMed ID: 26854595
    [TBL] [Abstract][Full Text] [Related]  

  • 8. PDE4 inhibitor, roflumilast protects cardiomyocytes against NO-induced apoptosis via activation of PKA and Epac dual pathways.
    Kwak HJ; Park KM; Choi HE; Chung KS; Lim HJ; Park HY
    Cell Signal; 2008 May; 20(5):803-14. PubMed ID: 18276108
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Elevation of cyclic AMP in Jurkat T-cells provokes distinct transcriptional responses through the protein kinase A (PKA) and exchange protein activated by cyclic AMP (EPAC) pathways.
    Fuld S; Borland G; Yarwood SJ
    Exp Cell Res; 2005 Sep; 309(1):161-73. PubMed ID: 15963501
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Cyclic AMP (cAMP)-mediated stimulation of adipocyte differentiation requires the synergistic action of Epac- and cAMP-dependent protein kinase-dependent processes.
    Petersen RK; Madsen L; Pedersen LM; Hallenborg P; Hagland H; Viste K; Døskeland SO; Kristiansen K
    Mol Cell Biol; 2008 Jun; 28(11):3804-16. PubMed ID: 18391018
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Insights into exchange factor directly activated by cAMP (EPAC) as potential target for cancer treatment.
    Kumar N; Prasad P; Jash E; Saini M; Husain A; Goldman A; Sehrawat S
    Mol Cell Biochem; 2018 Oct; 447(1-2):77-92. PubMed ID: 29417338
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Epac is a Rap1 guanine-nucleotide-exchange factor directly activated by cyclic AMP.
    de Rooij J; Zwartkruis FJ; Verheijen MH; Cool RH; Nijman SM; Wittinghofer A; Bos JL
    Nature; 1998 Dec; 396(6710):474-7. PubMed ID: 9853756
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A novel Epac-Rap-PP2A signaling module controls cAMP-dependent Akt regulation.
    Hong K; Lou L; Gupta S; Ribeiro-Neto F; Altschuler DL
    J Biol Chem; 2008 Aug; 283(34):23129-38. PubMed ID: 18550542
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Regulatory actions of 3',5'-cyclic adenosine monophosphate on osteoclast function: possible roles of Epac-mediated signaling.
    Jeevaratnam K; Salvage SC; Li M; Huang CL
    Ann N Y Acad Sci; 2018 Dec; 1433(1):18-28. PubMed ID: 29846007
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Functional roles of protein kinase A (PKA) and exchange protein directly activated by 3',5'-cyclic adenosine 5'-monophosphate (cAMP) 2 (EPAC2) in cAMP-mediated actions in adrenocortical cells.
    Aumo L; Rusten M; Mellgren G; Bakke M; Lewis AE
    Endocrinology; 2010 May; 151(5):2151-61. PubMed ID: 20233795
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A novel Epac-specific cAMP analogue demonstrates independent regulation of Rap1 and ERK.
    Enserink JM; Christensen AE; de Rooij J; van Triest M; Schwede F; Genieser HG; Døskeland SO; Blank JL; Bos JL
    Nat Cell Biol; 2002 Nov; 4(11):901-6. PubMed ID: 12402047
    [TBL] [Abstract][Full Text] [Related]  

  • 17. CAMP activates Rap1 in differentiating mouse male germ cells: a new signaling pathway mediated by the cAMP-activated exchange factor Epac?
    Berruti G
    Cell Mol Biol (Noisy-le-grand); 2003 May; 49(3):381-8. PubMed ID: 12887090
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Prostaglandin E2 inhibits specific lung fibroblast functions via selective actions of PKA and Epac-1.
    Huang SK; Wettlaufer SH; Chung J; Peters-Golden M
    Am J Respir Cell Mol Biol; 2008 Oct; 39(4):482-9. PubMed ID: 18421013
    [TBL] [Abstract][Full Text] [Related]  

  • 19. cAMP effects in neuroendocrine tumors: The role of Epac and PKA in cell proliferation and adhesion.
    Vitali E; Cambiaghi V; Spada A; Tresoldi A; Zerbi A; Peverelli E; Carnaghi C; Mantovani G; Lania AG
    Exp Cell Res; 2015 Dec; 339(2):241-51. PubMed ID: 26589262
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Epac as a tractable therapeutic target.
    Slika H; Mansour H; Nasser SA; Shaito A; Kobeissy F; Orekhov AN; Pintus G; Eid AH
    Eur J Pharmacol; 2023 Apr; 945():175645. PubMed ID: 36894048
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.