281 related articles for article (PubMed ID: 32901886)
21. ULK1 inhibition as a targeted therapeutic strategy for FLT3-ITD-mutated acute myeloid leukemia.
Hwang DY; Eom JI; Jang JE; Jeung HK; Chung H; Kim JS; Cheong JW; Min YH
J Exp Clin Cancer Res; 2020 May; 39(1):85. PubMed ID: 32393312
[TBL] [Abstract][Full Text] [Related]
22. PPM1D Knockdown Suppresses Cell Proliferation, Promotes Cell Apoptosis, and Activates p38 MAPK/p53 Signaling Pathway in Acute Myeloid Leukemia.
Li B; Hu J; He D; Chen Q; Liu S; Zhu X; Yu M
Technol Cancer Res Treat; 2020; 19():1533033820942312. PubMed ID: 32691668
[TBL] [Abstract][Full Text] [Related]
23. AMPK-ULK1-Mediated Autophagy Confers Resistance to BET Inhibitor JQ1 in Acute Myeloid Leukemia Stem Cells.
Jang JE; Eom JI; Jeung HK; Cheong JW; Lee JY; Kim JS; Min YH
Clin Cancer Res; 2017 Jun; 23(11):2781-2794. PubMed ID: 27864418
[No Abstract] [Full Text] [Related]
24. miR-10a as a therapeutic target and predictive biomarker for MDM2 inhibition in acute myeloid leukemia.
Vu TT; Stölzel F; Wang KW; Röllig C; Tursky ML; Molloy TJ; Ma DD
Leukemia; 2021 Jul; 35(7):1933-1948. PubMed ID: 33262524
[TBL] [Abstract][Full Text] [Related]
25. Blockade of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase and murine double minute synergistically induces Apoptosis in acute myeloid leukemia via BH3-only proteins Puma and Bim.
Zhang W; Konopleva M; Burks JK; Dywer KC; Schober WD; Yang JY; McQueen TJ; Hung MC; Andreeff M
Cancer Res; 2010 Mar; 70(6):2424-34. PubMed ID: 20215498
[TBL] [Abstract][Full Text] [Related]
26. CK1α ablation in keratinocytes induces p53-dependent, sunburn-protective skin hyperpigmentation.
Chang CH; Kuo CJ; Ito T; Su YY; Jiang ST; Chiu MH; Lin YH; Nist A; Mernberger M; Stiewe T; Ito S; Wakamatsu K; Hsueh YA; Shieh SY; Snir-Alkalay I; Ben-Neriah Y
Proc Natl Acad Sci U S A; 2017 Sep; 114(38):E8035-E8044. PubMed ID: 28878021
[TBL] [Abstract][Full Text] [Related]
27. Synergistic induction of p53 mediated apoptosis by valproic acid and nutlin-3 in acute myeloid leukemia.
McCormack E; Haaland I; Venås G; Forthun RB; Huseby S; Gausdal G; Knappskog S; Micklem DR; Lorens JB; Bruserud O; Gjertsen BT
Leukemia; 2012 May; 26(5):910-7. PubMed ID: 22064349
[TBL] [Abstract][Full Text] [Related]
28. Oncogenic RAS-induced CK1α drives nuclear FOXO proteolysis.
Zhang F; Virshup DM; Cheong JK
Oncogene; 2018 Jan; 37(3):363-376. PubMed ID: 28945225
[TBL] [Abstract][Full Text] [Related]
29. Casein kinase 1α regulates murine spermatogenesis via p53-Sox3 signaling.
Lu C; Zhang D; Zhang J; Li L; Qiu J; Gou K; Cui S
Development; 2022 Jul; 149(13):. PubMed ID: 35698877
[TBL] [Abstract][Full Text] [Related]
30. Mitogen-activated protein kinase kinase inhibition enhances nuclear proapoptotic function of p53 in acute myelogenous leukemia cells.
Kojima K; Konopleva M; Samudio IJ; Ruvolo V; Andreeff M
Cancer Res; 2007 Apr; 67(7):3210-9. PubMed ID: 17409429
[TBL] [Abstract][Full Text] [Related]
31. Dual inhibition of MDMX and MDM2 as a therapeutic strategy in leukemia.
Carvajal LA; Neriah DB; Senecal A; Benard L; Thiruthuvanathan V; Yatsenko T; Narayanagari SR; Wheat JC; Todorova TI; Mitchell K; Kenworthy C; Guerlavais V; Annis DA; Bartholdy B; Will B; Anampa JD; Mantzaris I; Aivado M; Singer RH; Coleman RA; Verma A; Steidl U
Sci Transl Med; 2018 Apr; 10(436):. PubMed ID: 29643228
[TBL] [Abstract][Full Text] [Related]
32. Suppression of casein kinase 1alpha in melanoma cells induces a switch in beta-catenin signaling to promote metastasis.
Sinnberg T; Menzel M; Kaesler S; Biedermann T; Sauer B; Nahnsen S; Schwarz M; Garbe C; Schittek B
Cancer Res; 2010 Sep; 70(17):6999-7009. PubMed ID: 20699366
[TBL] [Abstract][Full Text] [Related]
33. Ubiquitination of UVRAG by SMURF1 promotes autophagosome maturation and inhibits hepatocellular carcinoma growth.
Feng X; Jia Y; Zhang Y; Ma F; Zhu Y; Hong X; Zhou Q; He R; Zhang H; Jin J; Piao D; Huang H; Li Q; Qiu X; Zhang Z
Autophagy; 2019 Jul; 15(7):1130-1149. PubMed ID: 30686098
[TBL] [Abstract][Full Text] [Related]
34. Effect of casein kinase 1α inhibition on autophagy flux and the AKT/phospho-β-catenin (S552) axis in HCT116, a RAS-mutated colorectal cancer cell line.
Behrouj H; Seghatoleslam A; Mokarram P; Ghavami S
Can J Physiol Pharmacol; 2021 Mar; 99(3):284-293. PubMed ID: 33635146
[TBL] [Abstract][Full Text] [Related]
35. Targeted Degradation of MDM2 as a New Approach to Improve the Efficacy of MDM2-p53 Inhibitors.
Wurz RP; Cee VJ
J Med Chem; 2019 Jan; 62(2):445-447. PubMed ID: 30575392
[TBL] [Abstract][Full Text] [Related]
36. High Mdm4 levels suppress p53 activity and enhance its half-life in acute myeloid leukaemia.
Tan BX; Khoo KH; Lim TM; Lane DP
Oncotarget; 2014 Feb; 5(4):933-43. PubMed ID: 24659749
[TBL] [Abstract][Full Text] [Related]
37. Predictive Gene Signatures Determine Tumor Sensitivity to MDM2 Inhibition.
Ishizawa J; Nakamaru K; Seki T; Tazaki K; Kojima K; Chachad D; Zhao R; Heese L; Ma W; Ma MCJ; DiNardo C; Pierce S; Patel KP; Tse A; Davis RE; Rao A; Andreeff M
Cancer Res; 2018 May; 78(10):2721-2731. PubMed ID: 29490944
[TBL] [Abstract][Full Text] [Related]
38. Inhibition of Wild-Type p53-Expressing AML by the Novel Small Molecule HDM2 Inhibitor CGM097.
Weisberg E; Halilovic E; Cooke VG; Nonami A; Ren T; Sanda T; Simkin I; Yuan J; Antonakos B; Barys L; Ito M; Stone R; Galinsky I; Cowens K; Nelson E; Sattler M; Jeay S; Wuerthner JU; McDonough SM; Wiesmann M; Griffin JD
Mol Cancer Ther; 2015 Oct; 14(10):2249-59. PubMed ID: 26206331
[TBL] [Abstract][Full Text] [Related]
39. MDM2 Inhibitor, Nutlin 3a, Induces p53 Dependent Autophagy in Acute Leukemia by AMP Kinase Activation.
Borthakur G; Duvvuri S; Ruvolo V; Tripathi DN; Piya S; Burks J; Jacamo R; Kojima K; Ruvolo P; Fueyo-Margareto J; Konopleva M; Andreeff M
PLoS One; 2015; 10(10):e0139254. PubMed ID: 26440941
[TBL] [Abstract][Full Text] [Related]
40. Discovery of highly potent p53-MDM2 antagonists and structural basis for anti-acute myeloid leukemia activities.
Huang Y; Wolf S; Beck B; Köhler LM; Khoury K; Popowicz GM; Goda SK; Subklewe M; Twarda A; Holak TA; Dömling A
ACS Chem Biol; 2014 Mar; 9(3):802-11. PubMed ID: 24405416
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]