168 related articles for article (PubMed ID: 32904724)
21. The degradation of p53 and its major E3 ligase Mdm2 is differentially dependent on the proteasomal ubiquitin receptor S5a.
Sparks A; Dayal S; Das J; Robertson P; Menendez S; Saville MK
Oncogene; 2014 Sep; 33(38):4685-96. PubMed ID: 24121268
[TBL] [Abstract][Full Text] [Related]
22. p53 Ubiquitination and proteasomal degradation.
Love IM; Shi D; Grossman SR
Methods Mol Biol; 2013; 962():63-73. PubMed ID: 23150437
[TBL] [Abstract][Full Text] [Related]
23. Dual-site regulation of MDM2 E3-ubiquitin ligase activity.
Wallace M; Worrall E; Pettersson S; Hupp TR; Ball KL
Mol Cell; 2006 Jul; 23(2):251-63. PubMed ID: 16857591
[TBL] [Abstract][Full Text] [Related]
24. MDM2 acts downstream of p53 as an E3 ligase to promote FOXO ubiquitination and degradation.
Fu W; Ma Q; Chen L; Li P; Zhang M; Ramamoorthy S; Nawaz Z; Shimojima T; Wang H; Yang Y; Shen Z; Zhang Y; Zhang X; Nicosia SV; Zhang Y; Pledger JW; Chen J; Bai W
J Biol Chem; 2009 May; 284(21):13987-4000. PubMed ID: 19321440
[TBL] [Abstract][Full Text] [Related]
25. Quantitative assays of Mdm2 ubiquitin ligase activity and other ubiquitin-utilizing enzymes for inhibitor discovery.
Auger KR; Copeland RA; Lai Z
Methods Enzymol; 2005; 399():701-17. PubMed ID: 16338390
[TBL] [Abstract][Full Text] [Related]
26. Regulation of the E3 ubiquitin ligase activity of MDM2 by an N-terminal pseudo-substrate motif.
Worrall EG; Wawrzynow B; Worrall L; Walkinshaw M; Ball KL; Hupp TR
J Chem Biol; 2009 Aug; 2(3):113-29. PubMed ID: 19568783
[TBL] [Abstract][Full Text] [Related]
27. Functional inactivation of endogenous MDM2 and CHIP by HSP90 causes aberrant stabilization of mutant p53 in human cancer cells.
Li D; Marchenko ND; Schulz R; Fischer V; Velasco-Hernandez T; Talos F; Moll UM
Mol Cancer Res; 2011 May; 9(5):577-88. PubMed ID: 21478269
[TBL] [Abstract][Full Text] [Related]
28. A second p53 binding site in the central domain of Mdm2 is essential for p53 ubiquitination.
Ma J; Martin JD; Zhang H; Auger KR; Ho TF; Kirkpatrick RB; Grooms MH; Johanson KO; Tummino PJ; Copeland RA; Lai Z
Biochemistry; 2006 Aug; 45(30):9238-45. PubMed ID: 16866370
[TBL] [Abstract][Full Text] [Related]
29. Unlocking the Mdm2-p53 loop: ubiquitin is the key.
Clegg HV; Itahana K; Zhang Y
Cell Cycle; 2008 Feb; 7(3):287-92. PubMed ID: 18235222
[TBL] [Abstract][Full Text] [Related]
30. Mdm2 RING mutation enhances p53 transcriptional activity and p53-p300 interaction.
Clegg HV; Itahana Y; Itahana K; Ramalingam S; Zhang Y
PLoS One; 2012; 7(5):e38212. PubMed ID: 22666487
[TBL] [Abstract][Full Text] [Related]
31. Therapeutic opportunities in cancer therapy: targeting the p53-MDM2/MDMX interactions.
Munisamy M; Mukherjee N; Thomas L; Pham AT; Shakeri A; Zhao Y; Kolesar J; Rao PPN; Rangnekar VM; Rao M
Am J Cancer Res; 2021; 11(12):5762-5781. PubMed ID: 35018225
[TBL] [Abstract][Full Text] [Related]
32. MDM2 promotes ubiquitination and degradation of MDMX.
Pan Y; Chen J
Mol Cell Biol; 2003 Aug; 23(15):5113-21. PubMed ID: 12860999
[TBL] [Abstract][Full Text] [Related]
33. Inhibition of p53 degradation by Mdm2 acetylation.
Wang X; Taplick J; Geva N; Oren M
FEBS Lett; 2004 Mar; 561(1-3):195-201. PubMed ID: 15013777
[TBL] [Abstract][Full Text] [Related]
34. Mdm2 and MdmX RING Domains Play Distinct Roles in the Regulation of p53 Responses: A Comparative Study of Mdm2 and MdmX RING Domains in U2OS Cells.
Egorova O; Lau HH; McGraphery K; Sheng Y
Int J Mol Sci; 2020 Feb; 21(4):. PubMed ID: 32075226
[TBL] [Abstract][Full Text] [Related]
35. Regulation of p53 by the ubiquitin-conjugating enzymes UbcH5B/C in vivo.
Saville MK; Sparks A; Xirodimas DP; Wardrop J; Stevenson LF; Bourdon JC; Woods YL; Lane DP
J Biol Chem; 2004 Oct; 279(40):42169-81. PubMed ID: 15280377
[TBL] [Abstract][Full Text] [Related]
36. UBE4B, a ubiquitin chain assembly factor, is required for MDM2-mediated p53 polyubiquitination and degradation.
Wu H; Leng RP
Cell Cycle; 2011 Jun; 10(12):1912-5. PubMed ID: 21558803
[TBL] [Abstract][Full Text] [Related]
37. Mdm2 and MdmX partner to regulate p53.
Wang X; Jiang X
FEBS Lett; 2012 May; 586(10):1390-6. PubMed ID: 22673503
[TBL] [Abstract][Full Text] [Related]
38. RFWD3-Mdm2 ubiquitin ligase complex positively regulates p53 stability in response to DNA damage.
Fu X; Yucer N; Liu S; Li M; Yi P; Mu JJ; Yang T; Chu J; Jung SY; O'Malley BW; Gu W; Qin J; Wang Y
Proc Natl Acad Sci U S A; 2010 Mar; 107(10):4579-84. PubMed ID: 20173098
[TBL] [Abstract][Full Text] [Related]
39. SUMO-1 modification of Mdm2 prevents its self-ubiquitination and increases Mdm2 ability to ubiquitinate p53.
Buschmann T; Fuchs SY; Lee CG; Pan ZQ; Ronai Z
Cell; 2000 Jun; 101(7):753-62. PubMed ID: 10892746
[TBL] [Abstract][Full Text] [Related]
40. Ubiquitination and degradation of mutant p53.
Lukashchuk N; Vousden KH
Mol Cell Biol; 2007 Dec; 27(23):8284-95. PubMed ID: 17908790
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
