These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
3. Enhanced light-activated RNA interference using phosphorothioate-based dsRNA precursors of siRNA. Kala A; Friedman SH Pharm Res; 2011 Dec; 28(12):3050-7. PubMed ID: 21739319 [TBL] [Abstract][Full Text] [Related]
4. Amide-Modified RNA: Using Protein Backbone to Modulate Function of Short Interfering RNAs. Kotikam V; Rozners E Acc Chem Res; 2020 Sep; 53(9):1782-1790. PubMed ID: 32658452 [TBL] [Abstract][Full Text] [Related]
5. Chirality matters: stereo-defined phosphorothioate linkages at the termini of small interfering RNAs improve pharmacology in vivo. Jahns H; Taneja N; Willoughby JLS; Akabane-Nakata M; Brown CR; Nguyen T; Bisbe A; Matsuda S; Hettinger M; Manoharan RM; Rajeev KG; Maier MA; Zlatev I; Charisse K; Egli M; Manoharan M Nucleic Acids Res; 2022 Feb; 50(3):1221-1240. PubMed ID: 34268578 [TBL] [Abstract][Full Text] [Related]
7. Sequence, chemical, and structural variation of small interfering RNAs and short hairpin RNAs and the effect on mammalian gene silencing. Harborth J; Elbashir SM; Vandenburgh K; Manninga H; Scaringe SA; Weber K; Tuschl T Antisense Nucleic Acid Drug Dev; 2003 Apr; 13(2):83-105. PubMed ID: 12804036 [TBL] [Abstract][Full Text] [Related]
8. Synthesis and properties of 4'-C-aminoalkyl-2'-fluoro-modified RNA oligomers. Kano T; Katsuragi Y; Maeda Y; Ueno Y Bioorg Med Chem; 2018 Aug; 26(15):4574-4582. PubMed ID: 30097362 [TBL] [Abstract][Full Text] [Related]
10. Chemical modification resolves the asymmetry of siRNA strand degradation in human blood serum. Hoerter JA; Walter NG RNA; 2007 Nov; 13(11):1887-93. PubMed ID: 17804643 [TBL] [Abstract][Full Text] [Related]
11. Improved serum stability and biophysical properties of siRNAs following chemical modifications. Cho IS; Kim J; Lim DH; Ahn HC; Kim H; Lee KB; Lee YS Biotechnol Lett; 2008 Nov; 30(11):1901-8. PubMed ID: 18575806 [TBL] [Abstract][Full Text] [Related]
12. Synthesis of modified double stranded RNAs containing duplex regions between amide-linked RNA and RNA at both ends and enhanced nuclease resistance. Iwase R; Kurokawa R; Ueno J Nucleic Acids Symp Ser (Oxf); 2009; (53):119-20. PubMed ID: 19749289 [TBL] [Abstract][Full Text] [Related]
18. Gene silencing activity of siRNA molecules containing phosphorodithioate substitutions. Yang X; Sierant M; Janicka M; Peczek L; Martinez C; Hassell T; Li N; Li X; Wang T; Nawrot B ACS Chem Biol; 2012 Jul; 7(7):1214-20. PubMed ID: 22512638 [TBL] [Abstract][Full Text] [Related]
19. Effect of asymmetric terminal structures of short RNA duplexes on the RNA interference activity and strand selection. Sano M; Sierant M; Miyagishi M; Nakanishi M; Takagi Y; Sutou S Nucleic Acids Res; 2008 Oct; 36(18):5812-21. PubMed ID: 18782830 [TBL] [Abstract][Full Text] [Related]
20. A large-scale chemical modification screen identifies design rules to generate siRNAs with high activity, high stability and low toxicity. Bramsen JB; Laursen MB; Nielsen AF; Hansen TB; Bus C; Langkjaer N; Babu BR; Højland T; Abramov M; Van Aerschot A; Odadzic D; Smicius R; Haas J; Andree C; Barman J; Wenska M; Srivastava P; Zhou C; Honcharenko D; Hess S; Müller E; Bobkov GV; Mikhailov SN; Fava E; Meyer TF; Chattopadhyaya J; Zerial M; Engels JW; Herdewijn P; Wengel J; Kjems J Nucleic Acids Res; 2009 May; 37(9):2867-81. PubMed ID: 19282453 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]