These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

296 related articles for article (PubMed ID: 32912999)

  • 1. Structural basis for the inhibition of cGAS by nucleosomes.
    Kujirai T; Zierhut C; Takizawa Y; Kim R; Negishi L; Uruma N; Hirai S; Funabiki H; Kurumizaka H
    Science; 2020 Oct; 370(6515):455-458. PubMed ID: 32912999
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structural basis of nucleosome-dependent cGAS inhibition.
    Boyer JA; Spangler CJ; Strauss JD; Cesmat AP; Liu P; McGinty RK; Zhang Q
    Science; 2020 Oct; 370(6515):450-454. PubMed ID: 32913000
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structural mechanism of cGAS inhibition by the nucleosome.
    Pathare GR; Decout A; Glück S; Cavadini S; Makasheva K; Hovius R; Kempf G; Weiss J; Kozicka Z; Guey B; Melenec P; Fierz B; Thomä NH; Ablasser A
    Nature; 2020 Nov; 587(7835):668-672. PubMed ID: 32911482
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structural basis for nucleosome-mediated inhibition of cGAS activity.
    Cao D; Han X; Fan X; Xu RM; Zhang X
    Cell Res; 2020 Dec; 30(12):1088-1097. PubMed ID: 33051594
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The molecular basis of tight nuclear tethering and inactivation of cGAS.
    Zhao B; Xu P; Rowlett CM; Jing T; Shinde O; Lei Y; West AP; Liu WR; Li P
    Nature; 2020 Nov; 587(7835):673-677. PubMed ID: 32911481
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structural basis for sequestration and autoinhibition of cGAS by chromatin.
    Michalski S; de Oliveira Mann CC; Stafford CA; Witte G; Bartho J; Lammens K; Hornung V; Hopfner KP
    Nature; 2020 Nov; 587(7835):678-682. PubMed ID: 32911480
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The CRL5-SPSB3 ubiquitin ligase targets nuclear cGAS for degradation.
    Xu P; Liu Y; Liu C; Guey B; Li L; Melenec P; Ricci J; Ablasser A
    Nature; 2024 Mar; 627(8005):873-879. PubMed ID: 38418882
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The catalytic mechanism of cyclic GMP-AMP synthase (cGAS) and implications for innate immunity and inhibition.
    Hall J; Ralph EC; Shanker S; Wang H; Byrnes LJ; Horst R; Wong J; Brault A; Dumlao D; Smith JF; Dakin LA; Schmitt DC; Trujillo J; Vincent F; Griffor M; Aulabaugh AE
    Protein Sci; 2017 Dec; 26(12):2367-2380. PubMed ID: 28940468
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cellular uptake of extracellular nucleosomes induces innate immune responses by binding and activating cGMP-AMP synthase (cGAS).
    Wang H; Zang C; Ren M; Shang M; Wang Z; Peng X; Zhang Q; Wen X; Xi Z; Zhou C
    Sci Rep; 2020 Sep; 10(1):15385. PubMed ID: 32958884
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Viral DNA Sensors IFI16 and Cyclic GMP-AMP Synthase Possess Distinct Functions in Regulating Viral Gene Expression, Immune Defenses, and Apoptotic Responses during Herpesvirus Infection.
    Diner BA; Lum KK; Toettcher JE; Cristea IM
    mBio; 2016 Nov; 7(6):. PubMed ID: 27935834
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Unraveling the cGAS catalytic mechanism upon DNA activation through molecular dynamics simulations.
    Soler J; Paiva P; Ramos MJ; Fernandes PA; Brut M
    Phys Chem Chem Phys; 2021 Apr; 23(15):9524-9531. PubMed ID: 33885101
    [TBL] [Abstract][Full Text] [Related]  

  • 12. H2A and H2B tails are essential to properly reconstitute nucleosome core particles.
    Bertin A; Durand D; Renouard M; Livolant F; Mangenot S
    Eur Biophys J; 2007 Nov; 36(8):1083-94. PubMed ID: 17882413
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The N terminus of cGAS de-oligomerizes the cGAS:DNA complex and lifts the DNA size restriction of core-cGAS activity.
    Lee A; Park EB; Lee J; Choi BS; Kang SJ
    FEBS Lett; 2017 Mar; 591(6):954-961. PubMed ID: 28214358
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The structural basis of modified nucleosome recognition by 53BP1.
    Wilson MD; Benlekbir S; Fradet-Turcotte A; Sherker A; Julien JP; McEwan A; Noordermeer SM; Sicheri F; Rubinstein JL; Durocher D
    Nature; 2016 Aug; 536(7614):100-3. PubMed ID: 27462807
    [TBL] [Abstract][Full Text] [Related]  

  • 15. cGAS senses long and HMGB/TFAM-bound U-turn DNA by forming protein-DNA ladders.
    Andreeva L; Hiller B; Kostrewa D; Lässig C; de Oliveira Mann CC; Jan Drexler D; Maiser A; Gaidt M; Leonhardt H; Hornung V; Hopfner KP
    Nature; 2017 Sep; 549(7672):394-398. PubMed ID: 28902841
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structural dynamics of nucleosome core particle: comparison with nucleosomes containing histone variants.
    Ramaswamy A; Bahar I; Ioshikhes I
    Proteins; 2005 Feb; 58(3):683-96. PubMed ID: 15624215
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Phosphorylation and chromatin tethering prevent cGAS activation during mitosis.
    Li T; Huang T; Du M; Chen X; Du F; Ren J; Chen ZJ
    Science; 2021 Mar; 371(6535):. PubMed ID: 33542149
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Nuclear cGAS: guard or prisoner?
    de Oliveira Mann CC; Hopfner KP
    EMBO J; 2021 Aug; 40(16):e108293. PubMed ID: 34250619
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The histone variant macro-H2A preferentially forms "hybrid nucleosomes".
    Chakravarthy S; Luger K
    J Biol Chem; 2006 Sep; 281(35):25522-31. PubMed ID: 16803903
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Species-specific self-DNA detection mechanisms by mammalian cyclic GMP-AMP synthases.
    Mosallanejad K; Kennedy SN; Bahleda KM; Slavik KM; Zhou W; Govande AA; Hancks DC; Kranzusch PJ; Kagan JC
    Sci Immunol; 2023 Jan; 8(79):eabp9765. PubMed ID: 36662885
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.