BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

391 related articles for article (PubMed ID: 32926376)

  • 1. Chemical Modification of Guide RNAs for Improved CRISPR Activity in CD34+ Human Hematopoietic Stem and Progenitor Cells.
    Shapiro J; Tovin A; Iancu O; Allen D; Hendel A
    Methods Mol Biol; 2021; 2162():37-48. PubMed ID: 32926376
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Increasing CRISPR Efficiency and Measuring Its Specificity in HSPCs Using a Clinically Relevant System.
    Shapiro J; Iancu O; Jacobi AM; McNeill MS; Turk R; Rettig GR; Amit I; Tovin-Recht A; Yakhini Z; Behlke MA; Hendel A
    Mol Ther Methods Clin Dev; 2020 Jun; 17():1097-1107. PubMed ID: 32478125
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Minimal 2'-O-methyl phosphorothioate linkage modification pattern of synthetic guide RNAs for increased stability and efficient CRISPR-Cas9 gene editing avoiding cellular toxicity.
    Basila M; Kelley ML; Smith AVB
    PLoS One; 2017; 12(11):e0188593. PubMed ID: 29176845
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Optimized electroporation of CRISPR-Cas9/gRNA ribonucleoprotein complex for selection-free homologous recombination in human pluripotent stem cells.
    Xu H; Kita Y; Bang U; Gee P; Hotta A
    STAR Protoc; 2021 Dec; 2(4):100965. PubMed ID: 34825222
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Genome editing in human hematopoietic stem and progenitor cells via CRISPR-Cas9-mediated homology-independent targeted integration.
    Bloomer H; Smith RH; Hakami W; Larochelle A
    Mol Ther; 2021 Apr; 29(4):1611-1624. PubMed ID: 33309880
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Optimization of CRISPR/Cas9 Delivery to Human Hematopoietic Stem and Progenitor Cells for Therapeutic Genomic Rearrangements.
    Lattanzi A; Meneghini V; Pavani G; Amor F; Ramadier S; Felix T; Antoniani C; Masson C; Alibeu O; Lee C; Porteus MH; Bao G; Amendola M; Mavilio F; Miccio A
    Mol Ther; 2019 Jan; 27(1):137-150. PubMed ID: 30424953
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Chemically modified guide RNAs enhance CRISPR-Cas genome editing in human primary cells.
    Hendel A; Bak RO; Clark JT; Kennedy AB; Ryan DE; Roy S; Steinfeld I; Lunstad BD; Kaiser RJ; Wilkens AB; Bacchetta R; Tsalenko A; Dellinger D; Bruhn L; Porteus MH
    Nat Biotechnol; 2015 Sep; 33(9):985-989. PubMed ID: 26121415
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Highly Efficient Genome Editing of Murine and Human Hematopoietic Progenitor Cells by CRISPR/Cas9.
    Gundry MC; Brunetti L; Lin A; Mayle AE; Kitano A; Wagner D; Hsu JI; Hoegenauer KA; Rooney CM; Goodell MA; Nakada D
    Cell Rep; 2016 Oct; 17(5):1453-1461. PubMed ID: 27783956
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Highly Efficient Mouse Genome Editing by CRISPR Ribonucleoprotein Electroporation of Zygotes.
    Chen S; Lee B; Lee AY; Modzelewski AJ; He L
    J Biol Chem; 2016 Jul; 291(28):14457-67. PubMed ID: 27151215
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Global Transcriptional Response to CRISPR/Cas9-AAV6-Based Genome Editing in CD34
    Cromer MK; Vaidyanathan S; Ryan DE; Curry B; Lucas AB; Camarena J; Kaushik M; Hay SR; Martin RM; Steinfeld I; Bak RO; Dever DP; Hendel A; Bruhn L; Porteus MH
    Mol Ther; 2018 Oct; 26(10):2431-2442. PubMed ID: 30005866
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Ex vivo culture resting time impacts transplantation outcomes of genome-edited human hematopoietic stem and progenitor cells in xenograft mouse models.
    Demirci S; Khan MBN; Hinojosa G; Le A; Leonard A; Essawi K; Gudmundsdottir B; Liu X; Zeng J; Inam Z; Chu R; Uchida N; Araki D; London E; Butt H; Maitland SA; Bauer DE; Wolfe SA; Larochelle A; Tisdale JF
    Cytotherapy; 2024 Jun; 26(6):641-648. PubMed ID: 38506770
    [TBL] [Abstract][Full Text] [Related]  

  • 12. TRIAMF: A New Method for Delivery of Cas9 Ribonucleoprotein Complex to Human Hematopoietic Stem Cells.
    Yen J; Fiorino M; Liu Y; Paula S; Clarkson S; Quinn L; Tschantz WR; Klock H; Guo N; Russ C; Yu VWC; Mickanin C; Stevenson SC; Lee C; Yang Y
    Sci Rep; 2018 Nov; 8(1):16304. PubMed ID: 30389991
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Identification and Validation of CRISPR/Cas9 Off-Target Activity in Hematopoietic Stem and Progenitor Cells.
    Park SH; Lee CM; Bao G
    Methods Mol Biol; 2022; 2429():281-306. PubMed ID: 35507169
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Optimized Guide RNA Selection Improves
    Verhagen HJMP; Kuijk C; Rutgers L; Kokke AM; van der Meulen SA; van Mierlo G; Voermans C; van den Akker E
    CRISPR J; 2022 Oct; 5(5):702-716. PubMed ID: 36169633
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A Multiplexed CRISPR/Cas9 Editing System Based on the Endogenous tRNA Processing.
    Xie K; Yang Y
    Methods Mol Biol; 2019; 1917():63-73. PubMed ID: 30610628
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Electroporation-Based CRISPR/Cas9 Gene Editing Using Cas9 Protein and Chemically Modified sgRNAs.
    Laustsen A; Bak RO
    Methods Mol Biol; 2019; 1961():127-134. PubMed ID: 30912044
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A Versatile Tool for the Quantification of CRISPR/Cas9-Induced Genome Editing Events in Human Hematopoietic Cell Lines and Hematopoietic Stem/Progenitor Cells.
    Jayavaradhan R; Pillis DM; Malik P
    J Mol Biol; 2019 Jan; 431(1):102-110. PubMed ID: 29751014
    [TBL] [Abstract][Full Text] [Related]  

  • 18. PEG-Delivered CRISPR-Cas9 Ribonucleoproteins System for Gene-Editing Screening of Maize Protoplasts.
    Sant'Ana RRA; Caprestano CA; Nodari RO; Agapito-Tenfen SZ
    Genes (Basel); 2020 Sep; 11(9):. PubMed ID: 32887261
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Combined lentiviral- and RNA-mediated CRISPR/Cas9 delivery for efficient and traceable gene editing in human hematopoietic stem and progenitor cells.
    Yudovich D; Bäckström A; Schmiderer L; Žemaitis K; Subramaniam A; Larsson J
    Sci Rep; 2020 Dec; 10(1):22393. PubMed ID: 33372184
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Fluorescent labeling of CRISPR/Cas9 RNP for gene knockout in HSPCs and iPSCs reveals an essential role for GADD45b in stress response.
    Nasri M; Mir P; Dannenmann B; Amend D; Skroblyn T; Xu Y; Schulze-Osthoff K; Klimiankou M; Welte K; Skokowa J
    Blood Adv; 2019 Jan; 3(1):63-71. PubMed ID: 30622144
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 20.