BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

118 related articles for article (PubMed ID: 32927028)

  • 1. Biochemical, cellular and structural characterization of novel and selective ERK3 inhibitors.
    Grädler U; Busch M; Leuthner B; Raba M; Burgdorf L; Lehmann M; Linde N; Esdar C
    Bioorg Med Chem Lett; 2020 Nov; 30(22):127551. PubMed ID: 32927028
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Crystal Structure and Inhibitor Identifications Reveal Targeting Opportunity for the Atypical MAPK Kinase ERK3.
    Schröder M; Filippakopoulos P; Schwalm MP; Ferrer CA; Drewry DH; Knapp S; Chaikuad A
    Int J Mol Sci; 2020 Oct; 21(21):. PubMed ID: 33114754
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Docking of PRAK/MK5 to the atypical MAPKs ERK3 and ERK4 defines a novel MAPK interaction motif.
    Aberg E; Torgersen KM; Johansen B; Keyse SM; Perander M; Seternes OM
    J Biol Chem; 2009 Jul; 284(29):19392-401. PubMed ID: 19473979
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Activation loop phosphorylation of the atypical MAP kinases ERK3 and ERK4 is required for binding, activation and cytoplasmic relocalization of MK5.
    Déléris P; Rousseau J; Coulombe P; Rodier G; Tanguay PL; Meloche S
    J Cell Physiol; 2008 Dec; 217(3):778-88. PubMed ID: 18720373
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Activation of MK5/PRAK by the atypical MAP kinase ERK3 defines a novel signal transduction pathway.
    Seternes OM; Mikalsen T; Johansen B; Michaelsen E; Armstrong CG; Morrice NA; Turgeon B; Meloche S; Moens U; Keyse SM
    EMBO J; 2004 Dec; 23(24):4780-91. PubMed ID: 15577943
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The extracellular signal-regulated kinase 3 (mitogen-activated protein kinase 6 [MAPK6])-MAPK-activated protein kinase 5 signaling complex regulates septin function and dendrite morphology.
    Brand F; Schumacher S; Kant S; Menon MB; Simon R; Turgeon B; Britsch S; Meloche S; Gaestel M; Kotlyarov A
    Mol Cell Biol; 2012 Jul; 32(13):2467-78. PubMed ID: 22508986
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Characterization of the atypical MAPK ERK4 and its activation of the MAPK-activated protein kinase MK5.
    Kant S; Schumacher S; Singh MK; Kispert A; Kotlyarov A; Gaestel M
    J Biol Chem; 2006 Nov; 281(46):35511-9. PubMed ID: 16973613
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Scaffolding by ERK3 regulates MK5 in development.
    Schumacher S; Laass K; Kant S; Shi Y; Visel A; Gruber AD; Kotlyarov A; Gaestel M
    EMBO J; 2004 Dec; 23(24):4770-9. PubMed ID: 15538386
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Targeting ERK3/MK5 complex for treatment of obesity and diabetes.
    Loza-Valdes A; El-Merahbi R; Kassouf T; Demczuk A; Reuter S; Viera JT; Karwen T; Noh M; Löffler MC; Romero-Becerra R; Torres JL; Marcos M; Sabio G; Wojda U; Sumara G
    Biochem Biophys Res Commun; 2022 Jul; 612():119-125. PubMed ID: 35523049
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Triazolo[4,5-d]pyrimidin-5-amines based ERK3 inhibitors fail to demonstrate selective effects on adipocyte function.
    Belykh A; Hawro I; Kolczyńska-Matysiak K; Loza-Valdes A; Mieczkowski A; Sumara G
    Arch Biochem Biophys; 2024 Jan; 751():109825. PubMed ID: 37992885
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A functional link between the human cell cycle-regulatory phosphatase Cdc14A and the atypical mitogen-activated kinase Erk3.
    Hansen CA; Bartek J; Jensen S
    Cell Cycle; 2008 Feb; 7(3):325-34. PubMed ID: 18235225
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A novel role for atypical MAPK kinase ERK3 in regulating breast cancer cell morphology and migration.
    Al-Mahdi R; Babteen N; Thillai K; Holt M; Johansen B; Wetting HL; Seternes OM; Wells CM
    Cell Adh Migr; 2015; 9(6):483-94. PubMed ID: 26588708
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Germ Line Deletion Reveals a Nonessential Role of Atypical Mitogen-Activated Protein Kinase 6/Extracellular Signal-Regulated Kinase 3.
    Ronkina N; Schuster-Gossler K; Hansmann F; Kunze-Schumacher H; Sandrock I; Yakovleva T; Lafera J; Baumgärtner W; Krueger A; Prinz I; Gossler A; Kotlyarov A; Gaestel M
    Mol Cell Biol; 2019 Mar; 39(6):. PubMed ID: 30642948
    [TBL] [Abstract][Full Text] [Related]  

  • 14. ERK3-MK5 signaling regulates myogenic differentiation and muscle regeneration by promoting FoxO3 degradation.
    Soulez M; Tanguay PL; Dô F; Dort J; Crist C; Kotlyarov A; Gaestel M; Ferron M; Dumont NA; Meloche S
    J Cell Physiol; 2022 Apr; 237(4):2271-2287. PubMed ID: 35141958
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Activation loop phosphorylation of ERK3 is important for its kinase activity and ability to promote lung cancer cell invasiveness.
    Elkhadragy L; Alsaran H; Morel M; Long W
    J Biol Chem; 2018 Oct; 293(42):16193-16205. PubMed ID: 30166347
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The atypical mitogen-activated protein kinase ERK3 is essential for establishment of epithelial architecture.
    Takahashi C; Miyatake K; Kusakabe M; Nishida E
    J Biol Chem; 2018 Jun; 293(22):8342-8361. PubMed ID: 29674317
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Pyrazolopyridine inhibitors of B-RafV600E. Part 2: structure-activity relationships.
    Wenglowsky S; Ahrendt KA; Buckmelter AJ; Feng B; Gloor SL; Gradl S; Grina J; Hansen JD; Laird ER; Lunghofer P; Mathieu S; Moreno D; Newhouse B; Ren L; Risom T; Rudolph J; Seo J; Sturgis HL; Voegtli WC; Wen Z
    Bioorg Med Chem Lett; 2011 Sep; 21(18):5533-7. PubMed ID: 21802293
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Identification of the atypical MAPK Erk3 as a novel substrate for p21-activated kinase (Pak) activity.
    De la Mota-Peynado A; Chernoff J; Beeser A
    J Biol Chem; 2011 Apr; 286(15):13603-11. PubMed ID: 21317288
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Discovery and optimization of indazoles as potent and selective interleukin-2 inducible T cell kinase (ITK) inhibitors.
    Pastor RM; Burch JD; Magnuson S; Ortwine DF; Chen Y; De La Torre K; Ding X; Eigenbrot C; Johnson A; Liimatta M; Liu Y; Shia S; Wang X; Wu LC; Pei Z
    Bioorg Med Chem Lett; 2014 Jun; 24(11):2448-52. PubMed ID: 24767842
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Regulation of MAPK-activated protein kinase 5 activity and subcellular localization by the atypical MAPK ERK4/MAPK4.
    Aberg E; Perander M; Johansen B; Julien C; Meloche S; Keyse SM; Seternes OM
    J Biol Chem; 2006 Nov; 281(46):35499-510. PubMed ID: 16971392
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.