577 related articles for article (PubMed ID: 32927130)
21. Design and novel synthetic approach supported with molecular docking and biological evidence for naphthoquinone-hydrazinotriazolothiadiazine analogs as potential anticancer inhibiting topoisomerase-IIB.
Mohamady S; Gibriel AA; Ahmed MS; Hendy MS; Naguib BH
Bioorg Chem; 2020 Mar; 96():103641. PubMed ID: 32032844
[TBL] [Abstract][Full Text] [Related]
22. Synthesis and biological evaluation of benzo[a]phenazine derivatives as a dual inhibitor of topoisomerase I and II.
Zhuo ST; Li CY; Hu MH; Chen SB; Yao PF; Huang SL; Ou TM; Tan JH; An LK; Li D; Gu LQ; Huang ZS
Org Biomol Chem; 2013 Jun; 11(24):3989-4005. PubMed ID: 23657605
[TBL] [Abstract][Full Text] [Related]
23. New [1,2,4]triazolo[4,3-c]quinazolines as intercalative Topo II inhibitors: Design, synthesis, biological evaluation, and in silico studies.
Gaber AA; Sobhy M; Turky A; Eldehna WM; El-Sebaey SA; El-Metwally SA; El-Naggar AM; Ibrahim IM; Elkaeed EB; Metwaly AM; Eissa IH
PLoS One; 2023; 18(1):e0274081. PubMed ID: 36716311
[TBL] [Abstract][Full Text] [Related]
24. Design, synthesis and systematic evaluation of cytotoxic 3-heteroarylisoquinolinamines as topoisomerases inhibitors.
My Van HT; Woo H; Jeong HM; Khadka DB; Yang SH; Zhao C; Jin Y; Lee ES; Youl Lee K; Kwon Y; Cho WJ
Eur J Med Chem; 2014 Jul; 82():181-94. PubMed ID: 24904965
[TBL] [Abstract][Full Text] [Related]
25. Design, synthesis, biological evaluation, structure-activity relationship study, and mode of action of 2-phenol-4,6-dichlorophenyl-pyridines.
Shrestha A; Park S; Shin S; Man Kadayat T; Bist G; Katila P; Kwon Y; Lee ES
Bioorg Chem; 2018 Sep; 79():1-18. PubMed ID: 29715635
[TBL] [Abstract][Full Text] [Related]
26. Design and synthesis of thiadiazolo-carboxamide bridged β-carboline-indole hybrids: DNA intercalative topo-IIα inhibition with promising antiproliferative activity.
Tokala R; Sana S; Lakshmi UJ; Sankarana P; Sigalapalli DK; Gadewal N; Kode J; Shankaraiah N
Bioorg Chem; 2020 Dec; 105():104357. PubMed ID: 33091673
[TBL] [Abstract][Full Text] [Related]
27. A rational design strategy of the novel topoisomerase II inhibitors for the synthesis of the 4-O-(2-pyrazinecarboxylic)-4'-demethylepipodophyllotoxin with antitumor activity by diminishing the relaxation reaction of topoisomerase II-DNA decatenation.
Zhao W; Chen L; Li HM; Wang DJ; Li DS; Chen T; Yuan ZP; Tang YJ
Bioorg Med Chem; 2014 Jun; 22(11):2998-3007. PubMed ID: 24775914
[TBL] [Abstract][Full Text] [Related]
28. Synthesis and in vitro cytotoxicity evaluation of β-carboline-combretastatin carboxamides as apoptosis inducing agents: DNA intercalation and topoisomerase-II inhibition.
Jadala C; Sathish M; Reddy TS; Reddy VG; Tokala R; Bhargava SK; Shankaraiah N; Nagesh N; Kamal A
Bioorg Med Chem; 2019 Aug; 27(15):3285-3298. PubMed ID: 31227365
[TBL] [Abstract][Full Text] [Related]
29. Synthesis and biological evaluation of 4β-(thiazol-2-yl)amino-4'-O-demethyl-4-deoxypodophyllotoxins as topoisomerase-II inhibitors.
Sang CY; Tian HZ; Chen Y; Liu JF; Chen SW; Hui L
Bioorg Med Chem Lett; 2018 Jan; 28(2):71-76. PubMed ID: 29248296
[TBL] [Abstract][Full Text] [Related]
30. New fused pyrimidine derivatives with anticancer activity: Synthesis, topoisomerase II inhibition, apoptotic inducing activity and molecular modeling study.
Nemr MTM; AboulMagd AM
Bioorg Chem; 2020 Oct; 103():104134. PubMed ID: 32750610
[TBL] [Abstract][Full Text] [Related]
31. Triazoloquinoxalines-based DNA intercalators-Topo II inhibitors: design, synthesis, docking, ADMET and anti-proliferative evaluations.
Elwan A; Sakr H; El-Helby AA; El-Morsy A; Abdelgawad MA; Ghoneim MM; El-Sherbiny M; El-Adl K
J Enzyme Inhib Med Chem; 2022 Dec; 37(1):1556-1567. PubMed ID: 35635148
[TBL] [Abstract][Full Text] [Related]
32. Synthesis and antiproliferative activity of 9-benzylamino-6-chloro-2-methoxy-acridine derivatives as potent DNA-binding ligands and topoisomerase II inhibitors.
Zhang W; Zhang B; Zhang W; Yang T; Wang N; Gao C; Tan C; Liu H; Jiang Y
Eur J Med Chem; 2016 Jun; 116():59-70. PubMed ID: 27060757
[TBL] [Abstract][Full Text] [Related]
33. Design, synthesis, biological evaluation and molecular docking study on peptidomimetic analogues of XK469.
Xia QH; Hu W; Li C; Wu JF; Yang L; Han XM; Shen YM; Li ZY; Li X
Eur J Med Chem; 2016 Nov; 124():311-325. PubMed ID: 27597408
[TBL] [Abstract][Full Text] [Related]
34. Synthesis and biological evaluation of 2-phenol-4-chlorophenyl-6-aryl pyridines as topoisomerase II inhibitors and cytotoxic agents.
Thapa P; Kadayat TM; Park S; Shin S; Thapa Magar TB; Bist G; Shrestha A; Na Y; Kwon Y; Lee ES
Bioorg Chem; 2016 Jun; 66():145-59. PubMed ID: 27174797
[TBL] [Abstract][Full Text] [Related]
35. Identification of 3-(benzazol-2-yl)quinoxaline derivatives as potent anticancer compounds: Privileged structure-based design, synthesis, and bioactive evaluation in vitro and in vivo.
Liu QQ; Lu K; Zhu HM; Kong SL; Yuan JM; Zhang GH; Chen NY; Gu CX; Pan CX; Mo DL; Su GF
Eur J Med Chem; 2019 Mar; 165():293-308. PubMed ID: 30685528
[TBL] [Abstract][Full Text] [Related]
36. Discovery of new 3-methylquinoxalines as potential anti-cancer agents and apoptosis inducers targeting VEGFR-2: design, synthesis, and
Alanazi MM; Alaa E; Alsaif NA; Obaidullah AJ; Alkahtani HM; Al-Mehizia AA; Alsubaie SM; Taghour MS; Eissa IH
J Enzyme Inhib Med Chem; 2021 Dec; 36(1):1732-1750. PubMed ID: 34325596
[TBL] [Abstract][Full Text] [Related]
37. Synthesis and biological evaluation of imidazopyridinyl-1,3,4-oxadiazole conjugates as apoptosis inducers and topoisomerase IIα inhibitors.
Subba Rao AV; Vishnu Vardhan MV; Subba Reddy NV; Srinivasa Reddy T; Shaik SP; Bagul C; Kamal A
Bioorg Chem; 2016 Dec; 69():7-19. PubMed ID: 27656775
[TBL] [Abstract][Full Text] [Related]
38. Synthesis and evaluation of (18)F-labeled ATP competitive inhibitors of topoisomerase II as probes for imaging topoisomerase II expression.
Daumar P; Zeglis BM; Ramos N; Divilov V; Sevak KK; Pillarsetty N; Lewis JS
Eur J Med Chem; 2014 Oct; 86():769-81. PubMed ID: 25240701
[TBL] [Abstract][Full Text] [Related]
39. Design, synthesis and antiproliferative evaluation of new tricyclic fused thiazolopyrimidines targeting topoisomerase II: Molecular docking and apoptosis inducing activity.
Nemr MTM; Sonousi A; Marzouk AA
Bioorg Chem; 2020 Dec; 105():104446. PubMed ID: 33171405
[TBL] [Abstract][Full Text] [Related]
40. Quinolino[3,4-b]quinoxalines and pyridazino[4,3-c]quinoline derivatives: Synthesis, inhibition of topoisomerase IIα, G-quadruplex binding and cytotoxic properties.
Palluotto F; Sosic A; Pinato O; Zoidis G; Catto M; Sissi C; Gatto B; Carotti A
Eur J Med Chem; 2016 Nov; 123():704-717. PubMed ID: 27521587
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
