These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

202 related articles for article (PubMed ID: 32928875)

  • 1. Teleological role of L-2-hydroxyglutarate dehydrogenase in the kidney.
    Brinkley G; Nam H; Shim E; Kirkman R; Kundu A; Karki S; Heidarian Y; Tennessen JM; Liu J; Locasale JW; Guo T; Wei S; Gordetsky J; Johnson-Pais TL; Absher D; Rakheja D; Challa AK; Sudarshan S
    Dis Model Mech; 2020 Nov; 13(11):. PubMed ID: 32928875
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Renal L-2-hydroxyglutarate dehydrogenase activity promotes hypoxia tolerance and mitochondrial metabolism in Drosophila melanogaster.
    Mahmoudzadeh NH; Heidarian Y; Tourigny JP; Fitt AJ; Beebe K; Li H; Luhur A; Buddika K; Mungcal L; Kundu A; Policastro RA; Brinkley GJ; Zentner GE; Nemkov T; Pepin R; Chawla G; Sudarshan S; Rodan AR; D'Alessandro A; Tennessen JM
    Mol Metab; 2024 Nov; 89():102013. PubMed ID: 39182840
    [TBL] [Abstract][Full Text] [Related]  

  • 3. L-2-Hydroxyglutarate: an epigenetic modifier and putative oncometabolite in renal cancer.
    Shim EH; Livi CB; Rakheja D; Tan J; Benson D; Parekh V; Kho EY; Ghosh AP; Kirkman R; Velu S; Dutta S; Chenna B; Rea SL; Mishur RJ; Li Q; Johnson-Pais TL; Guo L; Bae S; Wei S; Block K; Sudarshan S
    Cancer Discov; 2014 Nov; 4(11):1290-8. PubMed ID: 25182153
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Biochemical and Epigenetic Insights into L-2-Hydroxyglutarate, a Potential Therapeutic Target in Renal Cancer.
    Shelar S; Shim EH; Brinkley GJ; Kundu A; Carobbio F; Poston T; Tan J; Parekh V; Benson D; Crossman DK; Buckhaults PJ; Rakheja D; Kirkman R; Sato Y; Ogawa S; Dutta S; Velu SE; Emberley E; Pan A; Chen J; Huang T; Absher D; Becker A; Kunick C; Sudarshan S
    Clin Cancer Res; 2018 Dec; 24(24):6433-6446. PubMed ID: 30108105
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A
    Li H; Hurlburt AJ; Tennessen JM
    Dis Model Mech; 2018 Sep; 11(9):. PubMed ID: 30108060
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Drosophila larvae synthesize the putative oncometabolite L-2-hydroxyglutarate during normal developmental growth.
    Li H; Chawla G; Hurlburt AJ; Sterrett MC; Zaslaver O; Cox J; Karty JA; Rosebrock AP; Caudy AA; Tennessen JM
    Proc Natl Acad Sci U S A; 2017 Feb; 114(6):1353-1358. PubMed ID: 28115720
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A mouse model of L-2-hydroxyglutaric aciduria, a disorder of metabolite repair.
    Rzem R; Achouri Y; Marbaix E; Schakman O; Wiame E; Marie S; Gailly P; Vincent MF; Veiga-da-Cunha M; Van Schaftingen E
    PLoS One; 2015; 10(3):e0119540. PubMed ID: 25763823
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Roles of the oncometabolite enantiomers of 2-hydroxyglutarate and their metabolism by diverse dehydrogenases.
    Garcia I; Cornely K; Peterson CN; Berkmen MB
    Essays Biochem; 2024 Oct; 68(2):161-171. PubMed ID: 38919140
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Blockage of L2HGDH-mediated S-2HG catabolism orchestrates macrophage polarization to elicit antitumor immunity.
    Feng S; Wang D; Jin Y; Huang S; Liang T; Sun W; Du X; Zhuo L; Shan C; Zhang W; Jing T; Zhao S; Hong R; You L; Liu G; Chen L; Ye D; Li X; Yang Y
    Cell Rep; 2024 Jun; 43(6):114300. PubMed ID: 38829739
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Renal oncometabolite L-2-hydroxyglutarate imposes a block in kidney tubulogenesis: Evidence for an epigenetic basis for the L-2HG-induced impairment of differentiation.
    Taub M; Mahmoudzadeh NH; Tennessen JM; Sudarshan S
    Front Endocrinol (Lausanne); 2022; 13():932286. PubMed ID: 36133305
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Another small molecule in the oncometabolite mix: L-2-Hydroxyglutarate in kidney cancer.
    Shim EH; Sudarshan S
    Oncoscience; 2015; 2(5):483-6. PubMed ID: 26097881
    [TBL] [Abstract][Full Text] [Related]  

  • 12. l-2-Hydroxyglutarate remodeling of the epigenome and epitranscriptome creates a metabolic vulnerability in kidney cancer models.
    Kundu A; Brinkley GJ; Nam H; Karki S; Kirkman R; Pandit M; Shim E; Widden H; Liu J; Heidarian Y; Mahmoudzadeh NH; Fitt AJ; Absher D; Ding HF; Crossman DK; Placzek WJ; Locasale JW; Rakheja D; McConathy JE; Ramachandran R; Bae S; Tennessen JM; Sudarshan S
    J Clin Invest; 2024 May; 134(13):. PubMed ID: 38743486
    [TBL] [Abstract][Full Text] [Related]  

  • 13.
    Ma S; Sun R; Jiang B; Gao J; Deng W; Liu P; He R; Cui J; Ji M; Yi W; Yang P; Wu X; Xiong Y; Qiu Z; Ye D; Guan KL
    Mol Cell Biol; 2017 Apr; 37(8):. PubMed ID: 28137912
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Plants Possess a Cyclic Mitochondrial Metabolic Pathway similar to the Mammalian Metabolic Repair Mechanism Involving Malate Dehydrogenase and l-2-Hydroxyglutarate Dehydrogenase.
    Hüdig M; Maier A; Scherrers I; Seidel L; Jansen EE; Mettler-Altmann T; Engqvist MK; Maurino VG
    Plant Cell Physiol; 2015 Sep; 56(9):1820-30. PubMed ID: 26203119
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Saccharomyces cerevisiae Forms D-2-Hydroxyglutarate and Couples Its Degradation to D-Lactate Formation via a Cytosolic Transhydrogenase.
    Becker-Kettern J; Paczia N; Conrotte JF; Kay DP; Guignard C; Jung PP; Linster CL
    J Biol Chem; 2016 Mar; 291(12):6036-58. PubMed ID: 26774271
    [TBL] [Abstract][Full Text] [Related]  

  • 16. MYC-driven accumulation of 2-hydroxyglutarate is associated with breast cancer prognosis.
    Terunuma A; Putluri N; Mishra P; Mathé EA; Dorsey TH; Yi M; Wallace TA; Issaq HJ; Zhou M; Killian JK; Stevenson HS; Karoly ED; Chan K; Samanta S; Prieto D; Hsu TY; Kurley SJ; Putluri V; Sonavane R; Edelman DC; Wulff J; Starks AM; Yang Y; Kittles RA; Yfantis HG; Lee DH; Ioffe OB; Schiff R; Stephens RM; Meltzer PS; Veenstra TD; Westbrook TF; Sreekumar A; Ambs S
    J Clin Invest; 2014 Jan; 124(1):398-412. PubMed ID: 24316975
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Oncometabolite L-2-hydroxyglurate directly induces vasculogenic mimicry through PHLDB2 in renal cell carcinoma.
    Wang H; Wang L; Zheng Q; Lu Z; Chen Y; Shen D; Xue D; Jiang M; Ding L; Zhang J; Wu H; Xia L; Qian J; Li G; Lu J
    Int J Cancer; 2021 Apr; 148(7):1743-1755. PubMed ID: 33320958
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Sensitive Determination of Onco-metabolites of D- and L-2-hydroxyglutarate Enantiomers by Chiral Derivatization Combined with Liquid Chromatography/Mass Spectrometry Analysis.
    Cheng QY; Xiong J; Huang W; Ma Q; Ci W; Feng YQ; Yuan BF
    Sci Rep; 2015 Oct; 5():15217. PubMed ID: 26458332
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Plant D-2-hydroxyglutarate dehydrogenase participates in the catabolism of lysine especially during senescence.
    Engqvist MK; Kuhn A; Wienstroer J; Weber K; Jansen EE; Jakobs C; Weber AP; Maurino VG
    J Biol Chem; 2011 Apr; 286(13):11382-90. PubMed ID: 21296880
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mitochondrial 2-hydroxyglutarate metabolism.
    Engqvist MK; Eßer C; Maier A; Lercher MJ; Maurino VG
    Mitochondrion; 2014 Nov; 19 Pt B():275-81. PubMed ID: 24561575
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.