330 related articles for article (PubMed ID: 32930582)
1. Natural Products for the Treatment of Pain: Chemistry and Pharmacology of Salvinorin A, Mitragynine, and Collybolide.
Chakraborty S; Majumdar S
Biochemistry; 2021 May; 60(18):1381-1400. PubMed ID: 32930582
[TBL] [Abstract][Full Text] [Related]
2. MGM-9 [(E)-methyl 2-(3-ethyl-7a,12a-(epoxyethanoxy)-9-fluoro-1,2,3,4,6,7,12,12b-octahydro-8-methoxyindolo[2,3-a]quinolizin-2-yl)-3-methoxyacrylate], a derivative of the indole alkaloid mitragynine: a novel dual-acting mu- and kappa-opioid agonist with potent antinociceptive and weak rewarding effects in mice.
Matsumoto K; Takayama H; Narita M; Nakamura A; Suzuki M; Suzuki T; Murayama T; Wongseripipatana S; Misawa K; Kitajima M; Tashima K; Horie S
Neuropharmacology; 2008 Aug; 55(2):154-65. PubMed ID: 18550129
[TBL] [Abstract][Full Text] [Related]
3. Pharmacological Comparison of Mitragynine and 7-Hydroxymitragynine: In Vitro Affinity and Efficacy for
Obeng S; Wilkerson JL; León F; Reeves ME; Restrepo LF; Gamez-Jimenez LR; Patel A; Pennington AE; Taylor VA; Ho NP; Braun T; Fortner JD; Crowley ML; Williamson MR; Pallares VLC; Mottinelli M; Lopera-Londoño C; McCurdy CR; McMahon LR; Hiranita T
J Pharmacol Exp Ther; 2021 Mar; 376(3):410-427. PubMed ID: 33384303
[TBL] [Abstract][Full Text] [Related]
4. Mitragynine/Corynantheidine Pseudoindoxyls As Opioid Analgesics with Mu Agonism and Delta Antagonism, Which Do Not Recruit β-Arrestin-2.
Váradi A; Marrone GF; Palmer TC; Narayan A; Szabó MR; Le Rouzic V; Grinnell SG; Subrath JJ; Warner E; Kalra S; Hunkele A; Pagirsky J; Eans SO; Medina JM; Xu J; Pan YX; Borics A; Pasternak GW; McLaughlin JP; Majumdar S
J Med Chem; 2016 Sep; 59(18):8381-97. PubMed ID: 27556704
[TBL] [Abstract][Full Text] [Related]
5. Synthetic and Receptor Signaling Explorations of the Mitragyna Alkaloids: Mitragynine as an Atypical Molecular Framework for Opioid Receptor Modulators.
Kruegel AC; Gassaway MM; Kapoor A; Váradi A; Majumdar S; Filizola M; Javitch JA; Sames D
J Am Chem Soc; 2016 Jun; 138(21):6754-64. PubMed ID: 27192616
[TBL] [Abstract][Full Text] [Related]
6. Effects of plant-derived analgesic compounds sinomenine and salvinorin A in infant rats.
Mascarenhas CJ; Liu R; Barr GA
J Integr Med; 2020 Mar; 18(2):174-180. PubMed ID: 31992510
[TBL] [Abstract][Full Text] [Related]
7. Opioid receptors and legal highs: Salvia divinorum and Kratom.
Babu KM; McCurdy CR; Boyer EW
Clin Toxicol (Phila); 2008 Feb; 46(2):146-52. PubMed ID: 18259963
[TBL] [Abstract][Full Text] [Related]
8. Chemistry and pharmacology of analgesic indole alkaloids from the rubiaceous plant, Mitragyna speciosa.
Takayama H
Chem Pharm Bull (Tokyo); 2004 Aug; 52(8):916-28. PubMed ID: 15304982
[TBL] [Abstract][Full Text] [Related]
9. Predicted Mode of Binding to and Allosteric Modulation of the μ-Opioid Receptor by Kratom's Alkaloids with Reported Antinociception
Zhou Y; Ramsey S; Provasi D; El Daibani A; Appourchaux K; Chakraborty S; Kapoor A; Che T; Majumdar S; Filizola M
Biochemistry; 2021 May; 60(18):1420-1429. PubMed ID: 33274929
[TBL] [Abstract][Full Text] [Related]
10. Orally active opioid μ/δ dual agonist MGM-16, a derivative of the indole alkaloid mitragynine, exhibits potent antiallodynic effect on neuropathic pain in mice.
Matsumoto K; Narita M; Muramatsu N; Nakayama T; Misawa K; Kitajima M; Tashima K; Devi LA; Suzuki T; Takayama H; Horie S
J Pharmacol Exp Ther; 2014 Mar; 348(3):383-92. PubMed ID: 24345467
[TBL] [Abstract][Full Text] [Related]
11. Collybolide is a novel biased agonist of κ-opioid receptors with potent antipruritic activity.
Gupta A; Gomes I; Bobeck EN; Fakira AK; Massaro NP; Sharma I; Cavé A; Hamm HE; Parello J; Devi LA
Proc Natl Acad Sci U S A; 2016 May; 113(21):6041-6. PubMed ID: 27162327
[TBL] [Abstract][Full Text] [Related]
12. A review of salvinorin analogs and their kappa-opioid receptor activity.
Roach JJ; Shenvi RA
Bioorg Med Chem Lett; 2018 May; 28(9):1436-1445. PubMed ID: 29615341
[TBL] [Abstract][Full Text] [Related]
13. The effects of mitragynine and morphine on schedule-controlled responding and antinociception in rats.
Hiranita T; Leon F; Felix JS; Restrepo LF; Reeves ME; Pennington AE; Obeng S; Avery BA; McCurdy CR; McMahon LR; Wilkerson JL
Psychopharmacology (Berl); 2019 Sep; 236(9):2725-2734. PubMed ID: 31098655
[TBL] [Abstract][Full Text] [Related]
14. Orally active opioid compounds from a non-poppy source.
Raffa RB; Beckett JR; Brahmbhatt VN; Ebinger TM; Fabian CA; Nixon JR; Orlando ST; Rana CA; Tejani AH; Tomazic RJ
J Med Chem; 2013 Jun; 56(12):4840-8. PubMed ID: 23517479
[TBL] [Abstract][Full Text] [Related]
15. Interactive Effects of
Obeng S; Leon F; Patel A; Zuarth Gonzalez JD; Chaves Da Silva L; Restrepo LF; Gamez-Jimenez LR; Ho NP; Guerrero Calvache MP; Pallares VLC; Helmes JA; Shiomitsu SK; Soto PL; McCurdy CR; McMahon LR; Wilkerson JL; Hiranita T
J Pharmacol Exp Ther; 2022 Dec; 383(3):182-198. PubMed ID: 36153006
[TBL] [Abstract][Full Text] [Related]
16. Indole alkaloids of a Thai medicinal herb, Mitragyna speciosa, that has opioid agonistic effect in guinea-pig ileum.
Horie S; Koyama F; Takayama H; Ishikawa H; Aimi N; Ponglux D; Matsumoto K; Murayama T
Planta Med; 2005 Mar; 71(3):231-6. PubMed ID: 15770543
[TBL] [Abstract][Full Text] [Related]
17. Antinociceptive effect of 7-hydroxymitragynine in mice: Discovery of an orally active opioid analgesic from the Thai medicinal herb Mitragyna speciosa.
Matsumoto K; Horie S; Ishikawa H; Takayama H; Aimi N; Ponglux D; Watanabe K
Life Sci; 2004 Mar; 74(17):2143-55. PubMed ID: 14969718
[TBL] [Abstract][Full Text] [Related]
18. Kappa Opioid Receptor Agonist Mesyl Sal B Attenuates Behavioral Sensitization to Cocaine with Fewer Aversive Side-Effects than Salvinorin A in Rodents.
Kivell BM; Paton KF; Kumar N; Morani AS; Culverhouse A; Shepherd A; Welsh SA; Biggerstaff A; Crowley RS; Prisinzano TE
Molecules; 2018 Oct; 23(10):. PubMed ID: 30314288
[TBL] [Abstract][Full Text] [Related]
19. Opioid receptor agonistic characteristics of mitragynine pseudoindoxyl in comparison with mitragynine derived from Thai medicinal plant Mitragyna speciosa.
Yamamoto LT; Horie S; Takayama H; Aimi N; Sakai S; Yano S; Shan J; Pang PK; Ponglux D; Watanabe K
Gen Pharmacol; 1999 Jul; 33(1):73-81. PubMed ID: 10428019
[TBL] [Abstract][Full Text] [Related]
20.
; ; . PubMed ID:
[No Abstract] [Full Text] [Related]
[Next] [New Search]
